2TGD

LACK OF THE TRANSITION STATE STABILIZATION SITE IS A FACTOR IN THE INACTIVITY OF TRYPSINOGEN, A SERINE PROTEASE ZYMOGEN. STRUCTURE OF DFP INHIBITED BOVINE TRYPSINOGEN AT 2.1 ANGSTROMS RESOLUTION

Summary for 2TGD

• Entry DOI: 10.2210/pdb2tgd/pdb
• Descriptor: TRYPSINOGEN, CALCIUM ION, DIISOPROPYL PHOSPHONATE, ... (4 entities in total)
• Functional Keywords: hydrolase zymogen (serine proteinase)
• Biological source: Bos taurus (cattle)
• Cellular location: Secreted, extracellular space: P00760
• Total number of polymer chains: 1
• Total formula weight: 24219.19

Authors

Jones, M.O.,Stroud, R.M. (deposition date: 1986-03-17, release date: 1986-05-07, Last modification date: 2017-11-29)

• Primary citation: Jones, M.O.,Stroud, R.M.; Lack of the Transition State Stabilization Site is a Factor in the Inactivity of Trypsinogen, a Serine Protease Zymogen. Structure of Dfp Inhibited Bovine Trypsinogen at 2.1 Angstroms Resolution; To be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)