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2TGD

LACK OF THE TRANSITION STATE STABILIZATION SITE IS A FACTOR IN THE INACTIVITY OF TRYPSINOGEN, A SERINE PROTEASE ZYMOGEN. STRUCTURE OF DFP INHIBITED BOVINE TRYPSINOGEN AT 2.1 ANGSTROMS RESOLUTION

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATRYPSINOGENpolymer22924013.01UniProt (P00760)
Pfam (PF00089)
In PDB
Bos taurus (cattle)
2ACALCIUM IONnon-polymer40.11Chemie (CA)
3ADIISOPROPYL PHOSPHONATEnon-polymer166.21Chemie (DFP)
4waterwater18.073Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight24013.0
Non-Polymers*Number of molecules2
Total formula weight206.2
All*Total formula weight24219.2
*Water molecules are not included.

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PDB entries from 2024-07-31

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