1EGU
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![BU of 1egu by Molmil](/molmil-images/mine/1egu) | CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE AT 1.56 A RESOLUTION | 分子名称: | HYALURONATE LYASE, SULFATE ION | 著者 | Li, S, Kelly, S.J, Lamani, E, Ferraroni, M, Jedrzejas, M.J. | 登録日 | 2000-02-16 | 公開日 | 2001-02-16 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Structural basis of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. EMBO J., 19, 2000
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1EHC
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![BU of 1ehc by Molmil](/molmil-images/mine/1ehc) | STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN CHEY | 分子名称: | CHEY, SULFATE ION | 著者 | Jiang, M, Bourret, R, Simon, M, Volz, K. | 登録日 | 1996-03-05 | 公開日 | 1997-05-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Uncoupled phosphorylation and activation in bacterial chemotaxis. The 2.3 A structure of an aspartate to lysine mutant at position 13 of CheY. J.Biol.Chem., 272, 1997
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1EM1
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![BU of 1em1 by Molmil](/molmil-images/mine/1em1) | X-RAY CRYSTAL STRUCTURE FOR HUMAN MANGANESE SUPEROXIDE DISMUTASE, Q143A | 分子名称: | MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE, SULFATE ION | 著者 | Leveque, V, Stroupe, M.E, Lepock, J.R, Cabelli, D.E, Tainer, J.A, Nick, H.S, Silverman, D.N. | 登録日 | 2000-03-14 | 公開日 | 2000-03-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Multiple replacements of glutamine 143 in human manganese superoxide dismutase: effects on structure, stability, and catalysis. Biochemistry, 39, 2000
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3W20
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![BU of 3w20 by Molmil](/molmil-images/mine/3w20) | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD | 分子名称: | Putative uncharacterized protein, ZINC ION | 著者 | Qin, H.M, Miyakawa, T, Jia, M.Z, Nakamura, A, Ohtsuka, J, Xue, Y.L, Kawashima, T, Kasahara, T, Hibi, M, Ogawa, J, Tanokura, M. | 登録日 | 2012-11-26 | 公開日 | 2013-07-17 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD Plos One, 8, 2013
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8CK3
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![BU of 8ck3 by Molmil](/molmil-images/mine/8ck3) | STRUCTURE OF HIF2A-ARNT HETERODIMER IN COMPLEX WITH (S)-1-(3,5-Difluoro-phenyl)-5,5-difluoro-3-methanesulfonyl-5,6-dihydro-4H-cyclopenta[c]thiophen-4-ol | 分子名称: | (4~{S})-1-[3,5-bis(fluoranyl)phenyl]-5,5-bis(fluoranyl)-3-methylsulfonyl-4,6-dihydrocyclopenta[c]thiophen-4-ol, Aryl hydrocarbon receptor nuclear translocator, DIMETHYL SULFOXIDE, ... | 著者 | Musil, D, Lehmannn, M, Diehl, L. | 登録日 | 2023-02-14 | 公開日 | 2023-07-19 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.707 Å) | 主引用文献 | Discovery of Cycloalkyl[ c ]thiophenes as Novel Scaffolds for Hypoxia-Inducible Factor-2 alpha Inhibitors. J.Med.Chem., 66, 2023
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3VWU
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3D1I
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![BU of 3d1i by Molmil](/molmil-images/mine/3d1i) | Structure of the Thioalkalivibrio nitratireducens cytochrome c nitrite reductase in a complex with nitrite | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, CALCIUM ION, Eight-heme nitrite reductase, ... | 著者 | Polyakov, K.M, Boyko, K.M, Slutsky, A, Tikhonova, T.V, Antipov, A.N, Zvyagilskaya, R.A, Popov, A.N, Lamzin, V.S, Bourenkov, G.P, Popov, V.O. | 登録日 | 2008-05-06 | 公開日 | 2009-05-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | High-resolution structural analysis of a novel octaheme cytochrome c nitrite reductase from the haloalkaliphilic bacterium Thioalkalivibrio nitratireducens J.Mol.Biol., 389, 2009
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8BZP
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![BU of 8bzp by Molmil](/molmil-images/mine/8bzp) | JNK3 (Mitogen-activated protein kinase 10) in Complex with Compound 23 bearing a C(sp3)F2Br moiety | 分子名称: | 1,2-ETHANEDIOL, 2-bromanyl-2,2-bis(fluoranyl)-~{N}-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ethanamide, BETA-MERCAPTOETHANOL, ... | 著者 | Stahlecker, J, Vaas, S, Stehle, T, Boeckler, F.M. | 登録日 | 2022-12-15 | 公開日 | 2023-08-02 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Principles and Applications of CF 2 X Moieties as Unconventional Halogen Bond Donors in Medicinal Chemistry, Chemical Biology, and Drug Discovery. J.Med.Chem., 66, 2023
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7ND0
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1EEU
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![BU of 1eeu by Molmil](/molmil-images/mine/1eeu) | M4L/Y(27D)D/Q89D/T94H mutant of LEN | 分子名称: | ISOPROPYL ALCOHOL, KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN) | 著者 | Pokkuluri, P.R, Cai, X, Gu, M, Stevens, F.J, Schiffer, M. | 登録日 | 2000-02-03 | 公開日 | 2001-02-03 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions. Protein Sci., 11, 2002
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5VY9
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![BU of 5vy9 by Molmil](/molmil-images/mine/5vy9) | S. cerevisiae Hsp104:casein complex, Middle Domain Conformation | 分子名称: | Alpha-S1-casein, Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Gates, S.N, Yokom, A.L, Lin, J.-B, Jackrel, M.E, Rizo, A.N, Kendsersky, N.M, Buell, C.E, Sweeny, E.A, Chuang, E, Torrente, M.P, Mack, K.L, Su, M, Shorter, J, Southworth, D.R. | 登録日 | 2017-05-24 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science, 357, 2017
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3VQU
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![BU of 3vqu by Molmil](/molmil-images/mine/3vqu) | CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN IN COMPLEX WITH 4-[(4-amino-5-cyano-6-ethoxypyridin-2- yl)amino]benzamide | 分子名称: | 4-[(4-amino-5-cyano-6-ethoxypyridin-2-yl)amino]benzamide, Dual specificity protein kinase TTK, IODIDE ION | 著者 | Kusakabe, K, Ide, N, Daigo, Y, Itoh, T, Higashino, K, Okano, Y, Tadano, G, Tachibana, Y, Sato, Y, Inoue, M, Wada, T, Iguchi, M, Kanazawa, T, Ishioka, Y, Dohi, K, Tagashira, S, Kido, Y, Sakamoto, S, Yasuo, K, Maeda, M, Yamamoto, T, Higaki, M, Endoh, T, Ueda, K, Shiota, T, Murai, H, Nakamura, Y. | 登録日 | 2012-03-30 | 公開日 | 2012-06-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Diaminopyridine-based potent and selective mps1 kinase inhibitors binding to an unusual flipped-Peptide conformation. Acs Med.Chem.Lett., 3, 2012
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7NCS
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1EJT
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![BU of 1ejt by Molmil](/molmil-images/mine/1ejt) | CRYSTAL STRUCTURE OF THE H219Q VARIANT OF KLEBSIELLA AEROGENES UREASE | 分子名称: | NICKEL (II) ION, UREASE ALPHA SUBUNIT, UREASE BETA SUBUNIT, ... | 著者 | Pearson, M.A, Park, I.S, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P. | 登録日 | 2000-03-04 | 公開日 | 2000-09-08 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Kinetic and structural characterization of urease active site variants. Biochemistry, 39, 2000
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1EM6
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![BU of 1em6 by Molmil](/molmil-images/mine/1em6) | HUMAN LIVER GLYCOGEN PHOSPHORYLASE A COMPLEXED WITH GLCNAC AND CP-526,423 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, BIS[5-CHLORO-1H-INDOL-2-YL-CARBONYL-AMINOETHYL]-ETHYLENE GLYCOL, LIVER GLYCOGEN PHOSPHORYLASE, ... | 著者 | Rath, V.L, Ammirati, M, Danley, D.E, Ekstrom, J.L, Hynes, T.R, Olson, T.V, Hoover, D.J. | 登録日 | 2000-03-16 | 公開日 | 2000-11-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Human liver glycogen phosphorylase inhibitors bind at a new allosteric site. Chem.Biol., 7, 2000
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8CC3
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![BU of 8cc3 by Molmil](/molmil-images/mine/8cc3) | Vibrio cholerae GbpA (LPMO domain) | 分子名称: | ACETATE ION, COPPER (II) ION, GlcNAc-binding protein A, ... | 著者 | Montserrat-Canals, M, Sorensen, H.V, Cordara, G, Krengel, U. | 登録日 | 2023-01-26 | 公開日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.128 Å) | 主引用文献 | Perdeuterated GbpA Enables Neutron Scattering Experiments of a Lytic Polysaccharide Monooxygenase. Acs Omega, 8, 2023
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3COG
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![BU of 3cog by Molmil](/molmil-images/mine/3cog) | Crystal structure of human cystathionase (Cystathionine gamma lyase) in complex with DL-propargylglycine | 分子名称: | (2S)-2-aminopent-4-enoic acid, Cystathionine gamma-lyase, DI(HYDROXYETHYL)ETHER, ... | 著者 | Collins, R, Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Olesen, K, Persson, C, Schuler, H, Svensson, L, Thorsell, A.G, Tresaugues, L, Van den Berg, S, Sagermark, J, Busam, R.D, Welin, M, Weigelt, J, Wikstrom, M, Structural Genomics Consortium (SGC) | 登録日 | 2008-03-28 | 公開日 | 2008-05-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S. J.Biol.Chem., 284, 2009
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8CC5
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![BU of 8cc5 by Molmil](/molmil-images/mine/8cc5) | Vibrio cholerae GbpA (LPMO domain) | 分子名称: | ACETATE ION, COPPER (II) ION, GlcNAc-binding protein A, ... | 著者 | Montserrat-Canals, M, Sorensen, H.V, Cordara, G, Krengel, U. | 登録日 | 2023-01-26 | 公開日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Perdeuterated GbpA Enables Neutron Scattering Experiments of a Lytic Polysaccharide Monooxygenase. Acs Omega, 8, 2023
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1E9X
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5W6J
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![BU of 5w6j by Molmil](/molmil-images/mine/5w6j) | Agrobacterium tumefaciens ADP-glucose pyrophosphorylase | 分子名称: | Glucose-1-phosphate adenylyltransferase, SULFATE ION | 著者 | Mascarenhas, R.N, Hill, B.L, Wu, R, Ballicora, M.A, Liu, D. | 登録日 | 2017-06-16 | 公開日 | 2018-11-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structural analysis reveals a pyruvate-binding activator site in theAgrobacterium tumefaciensADP-glucose pyrophosphorylase. J. Biol. Chem., 294, 2019
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1EJV
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![BU of 1ejv by Molmil](/molmil-images/mine/1ejv) | CRYSTAL STRUCTURE OF THE H320Q VARIANT OF KLEBSIELLA AEROGENES UREASE | 分子名称: | NICKEL (II) ION, UREASE ALPHA SUBUNIT, UREASE BETA SUBUNIT, ... | 著者 | Pearson, M.A, Park, I.S, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P. | 登録日 | 2000-03-04 | 公開日 | 2000-09-08 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Kinetic and structural characterization of urease active site variants. Biochemistry, 39, 2000
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7N1W
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![BU of 7n1w by Molmil](/molmil-images/mine/7n1w) | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Rawson, S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Chen, B. | 登録日 | 2021-05-28 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants. Science, 373, 2021
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7N1Y
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![BU of 7n1y by Molmil](/molmil-images/mine/7n1y) | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Rawson, S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Chen, B. | 登録日 | 2021-05-28 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants. Science, 373, 2021
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7N1U
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![BU of 7n1u by Molmil](/molmil-images/mine/7n1u) | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Rawson, S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Chen, B. | 登録日 | 2021-05-28 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants. Science, 373, 2021
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5WHZ
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![BU of 5whz by Molmil](/molmil-images/mine/5whz) | PGDM1400-10E8v4 CODV Fab | 分子名称: | Anti-HIV CODV-Fab Heavy chain, Anti-HIV CODV-Fab Light chain | 著者 | Lord, D.M, Wei, R.R. | 登録日 | 2017-07-18 | 公開日 | 2017-10-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.549 Å) | 主引用文献 | Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques. Science, 358, 2017
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