1QPB
 
 | | PYRUVATE DECARBOYXLASE FROM YEAST (FORM B) COMPLEXED WITH PYRUVAMIDE | | 分子名称: | MAGNESIUM ION, PYRUVAMIDE, PYRUVATE DECARBOXYLASE (FORM B), ... | | 著者 | Lu, G, Dobritzsch, D, Schneider, G. | | 登録日 | 1999-11-26 | | 公開日 | 2000-02-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Structural Basis of Substrate Activation in Yeast Pyruvate Decarboxylase a Crystallographic and Kinetic Study
Eur.J.Biochem., 267, 2000
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4MYW
 | | Structure of HSV-2 gD bound to nectin-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D, ... | | 著者 | Lu, G, Zhang, N, Qi, J, Li, Y, Chen, Z, Zheng, C, Yan, J, Gao, G.F. | | 登録日 | 2013-09-28 | | 公開日 | 2014-10-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.189 Å) | | 主引用文献 | Crystal structure of herpes simplex virus 2 gD bound to nectin-1 reveals a conserved mode of receptor recognition.
J.Virol., 88, 2014
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4N6X
 | | Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1 | | 分子名称: | CHLORIDE ION, Na(+)/H(+) exchange regulatory cofactor NHE-RF1/Chemokine Receptor CXCR2 fusion protein | | 著者 | Lu, G, Wu, Y, Jiang, Y, Brunzelle, J, Sirinupong, N, Li, C, Yang, Z. | | 登録日 | 2013-10-14 | | 公開日 | 2014-01-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.051 Å) | | 主引用文献 | New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping.
Plos One, 8, 2013
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2AWN
 | | Crystal structure of the ADP-Mg-bound E. Coli MALK (Crystallized with ATP-Mg) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Maltose/maltodextrin import ATP-binding protein malK | | 著者 | Lu, G, Westbrooks, J.M, Davidson, A.L, Chen, J. | | 登録日 | 2005-09-01 | | 公開日 | 2005-12-13 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AWO
 | | Crystal structure of the ADP-Mg-bound E. Coli MALK (Crystallized with ADP-Mg) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Maltose/maltodextrin import ATP-binding protein malK | | 著者 | Lu, G, Westbrooks, J.M, Davidson, A.L, Chen, J. | | 登録日 | 2005-09-01 | | 公開日 | 2005-12-13 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2CND
 | | STRUCTURAL STUDIES ON CORN NITRATE REDUCTASE: REFINED STRUCTURE OF THE CYTOCHROME B REDUCTASE FRAGMENT AT 2.5 ANGSTROMS, ITS ADP COMPLEX AND AN ACTIVE SITE MUTANT AND MODELING OF THE CYTOCHROME B DOMAIN | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NADH-DEPENDENT NITRATE REDUCTASE | | 著者 | Lu, G, Lindqvist, Y, Schneider, G. | | 登録日 | 1995-02-01 | | 公開日 | 1995-04-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural studies on corn nitrate reductase: refined structure of the cytochrome b reductase fragment at 2.5 A, its ADP complex and an active-site mutant and modeling of the cytochrome b domain.
J.Mol.Biol., 248, 1995
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1CNE
 | | STRUCTURAL STUDIES ON CORN NITRATE REDUCTASE: REFINED STRUCTURE OF THE CYTOCHROME B REDUCTASE FRAGMENT AT 2.5 ANGSTROMS, ITS ADP COMPLEX AND AN ACTIVE SITE MUTANT AND MODELING OF THE CYTOCHROME B DOMAIN | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NITRATE REDUCTASE | | 著者 | Lu, G, Lindqvist, Y, Schneider, G. | | 登録日 | 1995-02-01 | | 公開日 | 1995-04-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural studies on corn nitrate reductase: refined structure of the cytochrome b reductase fragment at 2.5 A, its ADP complex and an active-site mutant and modeling of the cytochrome b domain.
J.Mol.Biol., 248, 1995
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1CNF
 | | STRUCTURAL STUDIES ON CORN NITRATE REDUCTASE: REFINED STRUCTURE OF THE CYTOCHROME B REDUCTASE FRAGMENT AT 2.5 ANGSTROMS, ITS ADP COMPLEX AND AN ACTIVE SITE MUTANT AND MODELING OF THE CYTOCHROME B DOMAIN | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, NITRATE REDUCTASE | | 著者 | Lu, G, Lindqvist, Y, Schneider, G. | | 登録日 | 1995-02-01 | | 公開日 | 1995-04-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural studies on corn nitrate reductase: refined structure of the cytochrome b reductase fragment at 2.5 A, its ADP complex and an active-site mutant and modeling of the cytochrome b domain.
J.Mol.Biol., 248, 1995
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7Y9N
 | | an engineered 5-helix bundle derived from SARS-CoV-2 S2 in complex with HR2P | | 分子名称: | SARS-coV-2 S2 subunit, Spike protein S2',5HB-H2 | | 著者 | Lu, G.W, Lin, X, Guo, L.Y, Lin, S. | | 登録日 | 2022-06-25 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.885 Å) | | 主引用文献 | An engineered 5-helix bundle derived from SARS-CoV-2 S2 pre-binds sarbecoviral spike at both serological- and endosomal-pH to inhibit virus entry.
Emerg Microbes Infect, 11, 2022
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7YK1
 | | Structural basis of human PRPS2 filaments | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Lu, G.M, Hu, H.H, Liu, J.L. | | 登録日 | 2022-07-21 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Structural basis of human PRPS2 filaments.
Cell Biosci, 13, 2023
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1VCQ
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1VCP
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1ZPD
 | | PYRUVATE DECARBOXYLASE FROM ZYMOMONAS MOBILIS | | 分子名称: | CITRIC ACID, MAGNESIUM ION, MONO-{4-[(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-AMINO]-2-HYDROXY-3-MERCAPTO-PENT-3-ENYL-PHOSPHONO} ESTER, ... | | 著者 | Lu, G, Dobritzsch, D, Schneider, G. | | 登録日 | 1998-04-17 | | 公開日 | 1999-02-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | High resolution crystal structure of pyruvate decarboxylase from Zymomonas mobilis. Implications for substrate activation in pyruvate decarboxylases.
J.Biol.Chem., 273, 1998
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8GP6
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3SJO
 | | structure of EV71 3C in complex with Rupintrivir (AG7088) | | 分子名称: | 3C protease, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | | 著者 | Lu, G, Qi, J, Chen, Z, Xu, X, Gao, F, Lin, D, Qian, W, Liu, H, Jiang, H, Yan, J, Gao, G.F. | | 登録日 | 2011-06-21 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.
J.Virol., 85, 2011
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1FSA
 | | THE T-STATE STRUCTURE OF LYS 42 TO ALA MUTANT OF THE PIG KIDNEY FRUCTOSE 1,6-BISPHOSPHATASE EXPRESSED IN E. COLI | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, FRUCTOSE 1,6-BISPHOSPHATASE, ... | | 著者 | Lu, G, Stec, B, Giroux, E, Kantrowitz, E.R. | | 登録日 | 1996-08-24 | | 公開日 | 1997-09-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Evidence for an active T-state pig kidney fructose 1,6-bisphosphatase: interface residue Lys-42 is important for allosteric inhibition and AMP cooperativity.
Protein Sci., 5, 1996
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3RE9
 | | Crystal structure of sortaseC1 from Streptococcus suis | | 分子名称: | Sortase-like protein | | 著者 | Lu, G, Qi, J, Gao, F, Yan, J, Tang, J, Gao, G.F. | | 登録日 | 2011-04-04 | | 公開日 | 2011-06-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A novel "open-form" structure of sortaseC from Streptococcus suis.
Proteins, 79, 2011
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4MYV
 | | Free HSV-2 gD structure | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D | | 著者 | Lu, G, Zhang, N, Qi, J, Li, Y, Chen, Z, Zheng, C, Yan, J, Gao, G.F. | | 登録日 | 2013-09-28 | | 公開日 | 2014-10-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Crystal structure of herpes simplex virus 2 gD bound to nectin-1 reveals a conserved mode of receptor recognition.
J.Virol., 88, 2014
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2M67
 | | Full-length mercury transporter protein MerF in lipid bilayer membranes | | 分子名称: | MerF | | 著者 | Lu, G.J, Tian, Y, Vora, N, Marassi, F.M, Opella, S.J. | | 登録日 | 2013-03-27 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | The Structure of the Mercury Transporter MerF in Phospholipid Bilayers: A Large Conformational Rearrangement Results from N-Terminal Truncation.
J.Am.Chem.Soc., 135, 2013
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3SJ8
 | | Crystal structure of the 3C protease from coxsackievirus A16 | | 分子名称: | 3C protease | | 著者 | Lu, G, Qi, J, Chen, Z, Xu, X, Gao, F, Lin, D, Qian, W, Liu, H, Jiang, H, Yan, J, Gao, G.F. | | 登録日 | 2011-06-21 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | | 主引用文献 | Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.
J.Virol., 85, 2011
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3SJI
 | | crystal structure of CVA16 3C in complex with Rupintrivir (AG7088) | | 分子名称: | 3C protease, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, SODIUM ION | | 著者 | Lu, G, Qi, J, Chen, Z, Xu, X, Gao, F, Lin, D, Qian, W, Liu, H, Jiang, H, Yan, J, Gao, G.F. | | 登録日 | 2011-06-21 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | | 主引用文献 | Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.
J.Virol., 85, 2011
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2KV8
 | | Solution structure ofRGS12 PDZ domain | | 分子名称: | Regulator of G-protein signaling 12 | | 著者 | Lu, G, Ji, P, Huang, H. | | 登録日 | 2010-03-10 | | 公開日 | 2011-03-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Determining the Molecular Basis for the pH-dependent
Interaction between the PDZ of Human RGS12 and MEK2
To be Published
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3SJ9
 | | crystal structure of the C147A mutant 3C of CVA16 in complex with FAGLRQAVTQ peptide | | 分子名称: | 3C protease, FAGLRQAVTQ peptide | | 著者 | Lu, G, Qi, J, Chen, Z, Xu, X, Gao, F, Lin, D, Qian, W, Liu, H, Jiang, H, Yan, J, Gao, G.F. | | 登録日 | 2011-06-21 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | | 主引用文献 | Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.
J.Virol., 85, 2011
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3SJK
 | | Crystal structure of the C147A mutant 3C from enterovirus 71 | | 分子名称: | 3C protease, KPVLRTATVQGPSLDF peptide | | 著者 | Lu, G, Qi, J, Chen, Z, Xu, X, Gao, F, Lin, D, Qian, W, Liu, H, Jiang, H, Yan, J, Gao, G.F. | | 登録日 | 2011-06-21 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.096 Å) | | 主引用文献 | Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.
J.Virol., 85, 2011
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3Q0L
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