Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 30 件
4MAT
DownloadVisualize
BU of 4mat by Molmil
E.COLI METHIONINE AMINOPEPTIDASE HIS79ALA MUTANT
分子名称: PROTEIN (METHIONINE AMINOPEPTIDASE), SODIUM ION
著者Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W.
登録日1999-03-29
公開日1999-06-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis.
Biochemistry, 38, 1999
8FW6
DownloadVisualize
BU of 8fw6 by Molmil
Human Lactate Dehydrogenase A in Complex with Inhibitor CHK-336
分子名称: (2P)-2-{5-(cyclopropylmethyl)-3-(4-fluorophenyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Lowther, W.T, Gumpena, R.
登録日2023-01-20
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Human Lactate Dehydrogenase A in complex with inhibitor CHK-336
To Be Published
3MAT
DownloadVisualize
BU of 3mat by Molmil
E.COLI METHIONINE AMINOPEPTIDASE TRANSITION-STATE INHIBITOR COMPLEX
分子名称: COBALT (II) ION, METHIONINE AMINOPEPTIDASE, SODIUM ION, ...
著者Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W.
登録日1999-03-29
公開日1999-06-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis.
Biochemistry, 38, 1999
2MAT
DownloadVisualize
BU of 2mat by Molmil
E.COLI METHIONINE AMINOPEPTIDASE AT 1.9 ANGSTROM RESOLUTION
分子名称: COBALT (II) ION, PROTEIN (METHIONINE AMINOPEPTIDASE), SODIUM ION
著者Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W.
登録日1999-03-29
公開日1999-06-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis.
Biochemistry, 38, 1999
1L1D
DownloadVisualize
BU of 1l1d by Molmil
Crystal structure of the C-terminal methionine sulfoxide reductase domain (MsrB) of N. gonorrhoeae pilB
分子名称: CACODYLATE ION, peptide methionine sulfoxide reductase
著者Lowther, W.T, Weissbach, H, Etienne, F, Brot, N, Matthews, B.W.
登録日2002-02-15
公開日2002-05-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The mirrored methionine sulfoxide reductases of Neisseria gonorrhoeae pilB.
Nat.Struct.Biol., 9, 2002
1FVG
DownloadVisualize
BU of 1fvg by Molmil
CRYSTAL STRUCTURE OF BOVINE PEPTIDE METHIONINE SULFOXIDE REDUCTASE
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, PEPTIDE METHIONINE SULFOXIDE REDUCTASE
著者Lowther, W.T, Brot, N, Weissbach, H, Matthews, B.W.
登録日2000-09-19
公開日2000-11-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure and mechanism of peptide methionine sulfoxide reductase, an "anti-oxidation" enzyme.
Biochemistry, 39, 2000
1FVA
DownloadVisualize
BU of 1fva by Molmil
CRYSTAL STRUCTURE OF BOVINE METHIONINE SULFOXIDE REDUCTASE
分子名称: PEPTIDE METHIONINE SULFOXIDE REDUCTASE
著者Lowther, W.T, Brot, N, Weissbach, H, Matthews, B.W.
登録日2000-09-19
公開日2000-11-08
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and mechanism of peptide methionine sulfoxide reductase, an "anti-oxidation" enzyme.
Biochemistry, 39, 2000
1C24
DownloadVisualize
BU of 1c24 by Molmil
E. COLI METHIONINE AMINOPEPTIDASE: METHIONINE PHOSPHINATE COMPLEX
分子名称: (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC ACID, COBALT (II) ION, METHIONINE AMINOPEPTIDASE, ...
著者Lowther, W.T, Zhang, Y, Sampson, P.B, Honek, J.F, Matthews, B.W.
登録日1999-07-22
公開日1999-11-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
Biochemistry, 38, 1999
1C21
DownloadVisualize
BU of 1c21 by Molmil
E. COLI METHIONINE AMINOPEPTIDASE: METHIONINE COMPLEX
分子名称: COBALT (II) ION, METHIONINE, METHIONINE AMINOPEPTIDASE, ...
著者Lowther, W.T, Zhang, Y, Sampson, P.B, Honek, J.F, Matthews, B.W.
登録日1999-07-22
公開日1999-11-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
Biochemistry, 38, 1999
1C27
DownloadVisualize
BU of 1c27 by Molmil
E. COLI METHIONINE AMINOPEPTIDASE:NORLEUCINE PHOSPHONATE COMPLEX
分子名称: (1-AMINO-PENTYL)-PHOSPHONIC ACID, COBALT (II) ION, METHIONINE AMINOPEPTIDASE, ...
著者Lowther, W.T, Zhang, Y, Sampson, P.B, Honek, J.F, Matthews, B.W.
登録日1999-07-22
公開日1999-11-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
Biochemistry, 38, 1999
1C23
DownloadVisualize
BU of 1c23 by Molmil
E. COLI METHIONINE AMINOPEPTIDASE: METHIONINE PHOSPHONATE COMPLEX
分子名称: (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHONIC ACID, COBALT (II) ION, METHIONINE AMINOPEPTIDASE, ...
著者Lowther, W.T, Zhang, Y, Sampson, P.B, Honek, J.F, Matthews, B.W.
登録日1999-07-22
公開日1999-11-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
Biochemistry, 38, 1999
1C22
DownloadVisualize
BU of 1c22 by Molmil
E. COLI METHIONINE AMINOPEPTIDASE: TRIFLUOROMETHIONINE COMPLEX
分子名称: 2-AMINO-4-TRIFLUOROMETHYLSULFANYL-BUTYRIC ACID, COBALT (II) ION, METHIONINE AMINOPEPTIDASE, ...
著者Lowther, W.T, Zhang, Y, Sampson, P.B, Honek, J.F, Matthews, B.W.
登録日1999-07-22
公開日1999-11-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
Biochemistry, 38, 1999
6WSK
DownloadVisualize
BU of 6wsk by Molmil
Crystal Structure of the Cannabinoid Receptor 1 Interacting Protein 1a (CRIP1a)
分子名称: Endolysin,CB1 cannabinoid receptor-interacting protein 1 fusion
著者Booth, W.T, Howlett, A.C, Lowther, W.T.
登録日2020-05-01
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Cannabinoid receptor interacting protein 1a interacts with myristoylated G alpha i N terminus via a unique gapped beta-barrel structure.
J.Biol.Chem., 297, 2021
7LJ1
DownloadVisualize
BU of 7lj1 by Molmil
Human Prx1-Srx Decameric Complex
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
著者Forshaw, T.E, Reisz, J.A, Nelson, K.J, Gumpena, R, Lawson, J.R, Jonsson, T, Wu, H, Clodfelter, J.E, Johnson, L, Furdui, C.M, Lowther, W.T.
登録日2021-01-28
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Specificity of Human Sulfiredoxin for Reductant and Peroxiredoxin Oligomeric State.
Antioxidants (Basel), 10, 2021
2PX6
DownloadVisualize
BU of 2px6 by Molmil
Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat
分子名称: (2S,3S,5S)-5-[(N-FORMYL-L-LEUCYL)OXY]-2-HEXYL-3-HYDROXYHEXADECANOIC ACID, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Thioesterase domain
著者Pemble IV, C.W, Johnson, L.C, Kridel, S.J, Lowther, W.T.
登録日2007-05-14
公開日2007-07-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat.
Nat.Struct.Mol.Biol., 14, 2007
7M2N
DownloadVisualize
BU of 7m2n by Molmil
Crystal structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15
分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 5-[(5'-{1-(4-carboxy-1,3-thiazol-2-yl)-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-3-yl}-2'-fluoro[1,1'-biphenyl]-4-yl)oxy]-1H-1,2,3-triazole-4-carboxylic acid, ...
著者Gumpena, R, Ding, J, Powell, D.A, Lowther, W.T.
登録日2021-03-17
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Dual Glycolate Oxidase/Lactate Dehydrogenase A Inhibitors for Primary Hyperoxaluria
ACS Medicinal Chemistry Letters, 12, 2021
7M2O
DownloadVisualize
BU of 7m2o by Molmil
Crystal structure of Human Glycolate Oxidase with Inhibitor Compound 15
分子名称: 1,2-ETHANEDIOL, 5-[(5'-{1-(4-carboxy-1,3-thiazol-2-yl)-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-3-yl}-2'-fluoro[1,1'-biphenyl]-4-yl)oxy]-1H-1,2,3-triazole-4-carboxylic acid, DI(HYDROXYETHYL)ETHER, ...
著者Gumpena, R, Ding, J, Powell, D.A, Lowther, W.T.
登録日2021-03-17
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Dual Glycolate Oxidase/Lactate Dehydrogenase A Inhibitors for Primary Hyperoxaluria
ACS Medicinal Chemistry Letters, 12, 2021
2H30
DownloadVisualize
BU of 2h30 by Molmil
Crystal structure of the N-terminal domain of PilB from Neisseria gonorrhoeae
分子名称: Peptide methionine sulfoxide reductase msrA/msrB
著者Brot, N, Collet, J.F, Johnson, L.C, Jonsson, T.J, Weissbach, H, Lowther, W.T.
登録日2006-05-20
公開日2006-08-22
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The Thioredoxin Domain of Neisseria gonorrhoeae PilB Can Use Electrons from DsbD to Reduce Downstream Methionine Sulfoxide Reductases.
J.Biol.Chem., 281, 2006
5IJT
DownloadVisualize
BU of 5ijt by Molmil
Human Peroxiredoxin 2 Oxidized (SS)
分子名称: Peroxiredoxin-2, ZINC ION
著者Haynes, A.C, Bolduc, J.A, Lowther, W.T.
登録日2016-03-02
公開日2017-09-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.148 Å)
主引用文献Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins.
J. Biol. Chem., 293, 2018
3S5N
DownloadVisualize
BU of 3s5n by Molmil
Crystal Structure of Human 4-hydroxy-2-oxoglutarate Aldolase
分子名称: 1,2-ETHANEDIOL, 4-hydroxy-2-oxoglutarate aldolase, mitochondrial, ...
著者Riedel, T.J, Lowther, W.T.
登録日2011-05-23
公開日2011-10-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and Biochemical Studies of Human 4-hydroxy-2-oxoglutarate Aldolase: Implications for Hydroxyproline Metabolism in Primary Hyperoxaluria.
Plos One, 6, 2011
3S5O
DownloadVisualize
BU of 3s5o by Molmil
Crystal Structure of Human 4-hydroxy-2-oxoglutarate Aldolase Bound to Pyruvate
分子名称: 1,2-ETHANEDIOL, 4-hydroxy-2-oxoglutarate aldolase, mitochondrial, ...
著者Riedel, T.J, Lowther, W.T.
登録日2011-05-23
公開日2011-10-26
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural and Biochemical Studies of Human 4-hydroxy-2-oxoglutarate Aldolase: Implications for Hydroxyproline Metabolism in Primary Hyperoxaluria.
Plos One, 6, 2011
4XJV
DownloadVisualize
BU of 4xjv by Molmil
Crystal structure of human thioesterase 2
分子名称: CHLORIDE ION, S-acyl fatty acid synthase thioesterase, medium chain
著者Ritchie, M.K, Kridel, S.J, Lowther, W.T.
登録日2015-01-09
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure and Substrate Specificity of Human Thioesterase 2: INSIGHTS INTO THE MOLECULAR BASIS FOR THE MODULATION OF FATTY ACID SYNTHASE.
J.Biol.Chem., 291, 2016
3HY2
DownloadVisualize
BU of 3hy2 by Molmil
Crystal Structure of Sulfiredoxin in Complex with Peroxiredoxin I and ATP:Mg2+
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Peroxiredoxin-1, ...
著者Jonsson, T.J, Johnson, L.C, Lowther, W.T.
登録日2009-06-22
公開日2009-10-06
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Protein Engineering of the Quaternary Sulfiredoxin-Peroxiredoxin Enzyme-Substrate Complex Reveals the Molecular Basis for Cysteine Sulfinic Acid Phosphorylation
J.Biol.Chem., 284, 2009
3CYI
DownloadVisualize
BU of 3cyi by Molmil
Crystal Structure of Human Sulfiredoxin (Srx) in Complex with ATP:Mg2+
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Sulfiredoxin-1
著者Jonsson, T.J, Murray, M.S, Johnson, L.C, Lowther, W.T.
登録日2008-04-25
公開日2008-07-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Reduction of Cysteine Sulfinic Acid in Peroxiredoxin by Sulfiredoxin Proceeds Directly through a Sulfinic Phosphoryl Ester Intermediate.
J.Biol.Chem., 283, 2008
1XW4
DownloadVisualize
BU of 1xw4 by Molmil
Crystal Structure of Human Sulfiredoxin (Srx) in Complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Sulfiredoxin
著者Murray, M.S, Jonsson, T.J, Johnson, L.C, Poole, L.B, Lowther, W.T.
登録日2004-10-29
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin.
Biochemistry, 44, 2005

 

12>

226707

件を2024-10-30に公開中

PDB statisticsPDBj update infoContact PDBjnumon