3S5O

Crystal Structure of Human 4-hydroxy-2-oxoglutarate Aldolase Bound to Pyruvate

Summary for 3S5O

• Entry DOI: 10.2210/pdb3s5o/pdb
• Related: 3S5N
• Descriptor: 4-hydroxy-2-oxoglutarate aldolase, mitochondrial, 1,2-ETHANEDIOL, POTASSIUM ION, ... (4 entities in total)
• Functional Keywords: aldolase, beta barrel, schiff base, hydroxyproline metabolism, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion (By similarity): Q86XE5
• Total number of polymer chains: 1
• Total formula weight: 33391.28

Authors

Riedel, T.J.,Lowther, W.T. (deposition date: 2011-05-23, release date: 2011-10-26)

• Primary citation: Riedel, T.J.,Johnson, L.C.,Knight, J.,Hantgan, R.R.,Holmes, R.P.,Lowther, W.T.; Structural and Biochemical Studies of Human 4-hydroxy-2-oxoglutarate Aldolase: Implications for Hydroxyproline Metabolism in Primary Hyperoxaluria.; Plos One, 6:e26021-e26021, 2011; PubMed: 21998747; DOI: 10.1371/journal.pone.0026021

Experimental method

X-RAY DIFFRACTION (1.97 Å)