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PDB: 14 件
4P9F
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BU of 4p9f by Molmil
E. coli McbR/YncC
分子名称: HTH-type transcriptional regulator mcbR
著者Lord, D.M, Page, R, Peti, W.
登録日2014-04-03
公開日2015-01-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献McbR/YncC: Implications for the Mechanism of Ligand and DNA Binding by a Bacterial GntR Transcriptional Regulator Involved in Biofilm Formation.
Biochemistry, 53, 2014
5WHZ
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BU of 5whz by Molmil
PGDM1400-10E8v4 CODV Fab
分子名称: Anti-HIV CODV-Fab Heavy chain, Anti-HIV CODV-Fab Light chain
著者Lord, D.M, Wei, R.R.
登録日2017-07-18
公開日2017-10-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.549 Å)
主引用文献Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques.
Science, 358, 2017
6O89
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Anti-CD28xCD3 CODV Fab
分子名称: Anti-CD28xCD3 CODV-Fab Heavy chain, Anti-CD28xCD3 CODV-Fab Light chain
著者Lord, D.M, Wei, R.R.
登録日2019-03-09
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation
Nat Cancer, 1, 2020
7JKB
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2xVH Fab
分子名称: Anti-Her2, Anti-lysozyme
著者Lord, D.M, Zhou, Y.F.
登録日2020-07-28
公開日2020-11-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific.
Antibodies, 9, 2020
6AMM
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CAT192 Fab Insertion Mutant H0/L1
分子名称: CAT192 Fab Heavy chain, CAT192 Fab Light chain
著者Lord, D.M, Wei, R.R.
登録日2017-08-10
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGF beta 1 antibody.
MAbs, 10, 2018
6O8D
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Anti-CD28xCD3 CODV Fab bound to CD28
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-CD28xCD3 CODV Fab Heavy chain, ...
著者Lord, D.M, Wei, R.R.
登録日2019-03-09
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.547 Å)
主引用文献Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation
To Be Published
6AMJ
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CAT192 Fab Wild Type
分子名称: CAT192 Fab heavy chain, CAT192 Fab light chain, DI(HYDROXYETHYL)ETHER, ...
著者Lord, D.M, Wei, R.R.
登録日2017-08-09
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGF beta 1 antibody.
MAbs, 10, 2018
6AO0
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BU of 6ao0 by Molmil
CAT192 Fab Insertion Mutant H2/L2
分子名称: CAT192 Fab Heavy chain, CAT192 Fab Light chain, SULFATE ION
著者Lord, D.M, Wei, R.R.
登録日2017-08-15
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGF beta 1 antibody.
MAbs, 10, 2018
6ANP
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CAT192 Fab Insertion Mutant H5/L0
分子名称: CAT192 Fab Heavy chain, CAT192 Fab Light chain
著者Lord, D.M, Wei, R.R.
登録日2017-08-14
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGF beta 1 antibody.
MAbs, 10, 2018
8TNO
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UNC_239 from Chroma generative model
分子名称: UNC_239
著者Ng-Thow-Hing, C, Van Vlack, E.R, Lord, D.M.
登録日2023-08-02
公開日2023-11-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Illuminating protein space with a programmable generative model.
Nature, 623, 2023
8TNM
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UNC_079 from Chroma generative model
分子名称: UNC_079
著者Ng-Thow-Hing, C, Van Vlack, E.R, Lord, D.M.
登録日2023-08-02
公開日2023-11-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Illuminating protein space with a programmable generative model.
Nature, 623, 2023
6VC9
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TB19 complex
分子名称: 1,2-ETHANEDIOL, 5'-nucleotidase, ecto (CD73), ...
著者Zhou, Y.F, Lord, D.M.
登録日2019-12-20
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms.
J.Biol.Chem., 295, 2020
6VCA
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BU of 6vca by Molmil
TB38 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-nucleotidase, ...
著者Zhou, Y.F, Lord, D.M.
登録日2019-12-20
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.73 Å)
主引用文献A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms.
J.Biol.Chem., 295, 2020
5W1E
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BU of 5w1e by Molmil
PobR in complex with PHB
分子名称: GLYCEROL, P-HYDROXYBENZOIC ACID, Putative transcriptional regulator, ...
著者Page, R, Peti, W, Lord, D.M, Bajaj, R, Zhang, R.
登録日2017-06-02
公開日2017-12-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献A peculiar IclR family transcription factor regulates para-hydroxybenzoate catabolism in Streptomyces coelicolor.
Nucleic Acids Res., 46, 2018

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件を2024-07-17に公開中

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