Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 25 件
1OMW
DownloadVisualize
BU of 1omw by Molmil
Crystal Structure of the complex between G Protein-Coupled Receptor Kinase 2 and Heterotrimeric G Protein beta 1 and gamma 2 subunits
分子名称: G-protein coupled receptor kinase 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1
著者Lodowski, D.T, Pitcher, J.A, Capel, W.D, Lefkowitz, R.J, Tesmer, J.J.G.
登録日2003-02-26
公開日2003-06-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Keeping G proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and G-Beta-Gamma
Science, 300, 2003
1YM7
DownloadVisualize
BU of 1ym7 by Molmil
G Protein-Coupled Receptor Kinase 2 (GRK2)
分子名称: Beta-adrenergic receptor kinase 1
著者Lodowski, D.T, Barnhill, J.F, Pyskadlo, R.M, Ghirlando, R, Sterne-Marr, R, Tesmer, J.J.G.
登録日2005-01-20
公開日2005-07-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献The role of Gbetagamma and domain interfaces in the activation of G protein-coupled receptor kinase 2
Biochemistry, 44, 2005
2ACX
DownloadVisualize
BU of 2acx by Molmil
Crystal Structure of G protein coupled receptor kinase 6 bound to AMPPNP
分子名称: G protein-coupled receptor kinase 6, MAGNESIUM ION, PHOSPHATE ION, ...
著者Lodowski, D.T, Tesmer, V.M, Benovic, J.L, Tesmer, J.J.
登録日2005-07-19
公開日2006-04-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Structure of G Protein-coupled Receptor Kinase (GRK)-6 Defines a Second Lineage of GRKs.
J.Biol.Chem., 281, 2006
2I37
DownloadVisualize
BU of 2i37 by Molmil
Crystal structure of a photoactivated rhodopsin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Rhodopsin, ...
著者Lodowski, D.T, Stenkamp, R.E, Salom, D, Le Trong, I, Palczewski, K.
登録日2006-08-17
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (4.15 Å)
主引用文献Crystal structure of a photoactivated deprotonated intermediate of rhodopsin.
Proc.Natl.Acad.Sci.Usa, 103, 2006
6N1G
DownloadVisualize
BU of 6n1g by Molmil
Crystal structure of Aquaglyceroporin AQP7
分子名称: Aquaporin-7, GLYCEROL
著者Vahedi-Faridi, A, Lodowski, D, Kowatz, T.
登録日2018-11-08
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.995 Å)
主引用文献Aquaporin-7: A Dynamic Aquaglyceroporin With Greater Water and Glycerol Permeability Than Its Bacterial Homolog GlpF.
Front Physiol, 11, 2020
4YEU
DownloadVisualize
BU of 4yeu by Molmil
ELIC-GLIC chimera in the resting conformation
分子名称: Cys-loop ligand-gated ion channel,Proton-gated ion channel
著者Schmandt, N, Vivien, Y, Lodowski, D, Chakrapani, S.
登録日2015-02-24
公開日2015-09-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献An ELIC-GLIC Chimera Reveals Distinct Pathways of Activation in the Cys-loop receptors
To Be Published
4X1H
DownloadVisualize
BU of 4x1h by Molmil
Opsin/G(alpha) peptide complex stabilized by nonyl-glucoside
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-terminal derived peptide of guanine nucleotide-binding protein G(t) subunit alpha-1, PALMITIC ACID, ...
著者Blankenship, E, Lodowski, D.T.
登録日2014-11-24
公開日2015-11-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献The High-Resolution Structure of Activated Opsin Reveals a Conserved Solvent Network in the Transmembrane Region Essential for Activation.
Structure, 23, 2015
5KWM
DownloadVisualize
BU of 5kwm by Molmil
S. erythraea trypsin long construct apoenzyme
分子名称: Trypsin
著者Blankenship, E, Lodowski, D.T.
登録日2016-07-18
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (0.777 Å)
主引用文献S. erythraea trypsin long construct
To be Published
5HI9
DownloadVisualize
BU of 5hi9 by Molmil
Structure of the full-length TRPV2 channel by cryo-electron microscopy
分子名称: Transient Receptor Potential Cation Channel Subfamily V Member 2
著者Huynh, K.W, Cohen, M.R, Jiansen, J, Samanta, A, Lodowski, D.T, Zhou, Z.H, Moiseenkova-Bell, V.Y.
登録日2016-01-11
公開日2016-03-30
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure of the full-length TRPV2 channel by cryo-EM.
Nat Commun, 7, 2016
4M7G
DownloadVisualize
BU of 4m7g by Molmil
Streptomyces Erythraeus Trypsin
分子名称: Trypsin-like protease
著者Blankenship, E, Vukoti, K, Miyagi, M, Lodowski, D.T.
登録日2013-08-12
公開日2014-03-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (0.81 Å)
主引用文献Conformational flexibility in the catalytic triad revealed by the high-resolution crystal structure of Streptomyces erythraeus trypsin in an unliganded state.
Acta Crystallogr.,Sect.D, 70, 2014
4OJ2
DownloadVisualize
BU of 4oj2 by Molmil
The structure of aquaporin
分子名称: Aquaporin-2
著者Vahedi-Faridi, A, Lodowski, D, Engel, A, Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS)
登録日2014-01-20
公開日2014-05-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献The structure of aquaporin
To be Published
3FSN
DownloadVisualize
BU of 3fsn by Molmil
Crystal structure of RPE65 at 2.14 angstrom resolution
分子名称: FE (II) ION, Retinal pigment epithelium-specific 65 kDa protein, TETRAETHYLENE GLYCOL
著者Kiser, P.D, Lodowski, D.T, Palczewski, K.
登録日2009-01-11
公開日2009-09-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal structure of native RPE65, the retinoid isomerase of the visual cycle.
Proc.Natl.Acad.Sci.USA, 106, 2009
4DPZ
DownloadVisualize
BU of 4dpz by Molmil
Crystal structure of human HRASLS2
分子名称: HRAS-like suppressor 2
著者Kiser, P.D, Golczak, M, Sears, A.E, Lodowski, D.T, Palczewski, K.
登録日2012-02-14
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins.
J.Biol.Chem., 287, 2012
4DOT
DownloadVisualize
BU of 4dot by Molmil
Crystal structure of human HRASLS3.
分子名称: Group XVI phospholipase A2
著者Kiser, P.D, Golczak, M, Sears, A.E, Lodowski, D.T, Palczewski, K.
登録日2012-02-10
公開日2012-05-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins.
J.Biol.Chem., 287, 2012
3CIK
DownloadVisualize
BU of 3cik by Molmil
Human GRK2 in Complex with Gbetagamma subunits
分子名称: Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Tesmer, J.J.G, Lodowski, D.T.
登録日2008-03-11
公開日2009-02-17
最終更新日2012-03-07
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol.
J.Med.Chem., 53, 2010
6B5V
DownloadVisualize
BU of 6b5v by Molmil
Structure of TRPV5 in complex with econazole
分子名称: 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, CALCIUM ION, Transient receptor potential cation channel subfamily V member 5
著者Hughes, T.E.T, Lodowski, D.T, Huynh, K.W, Yazici, A, del Rosario, J, Kapoor, A, Basak, S, Samanta, A, Chakrapani, S, Zhou, Z.H, Filizola, M, Rohacs, T, Han, S, Moiseenkova-Bell, V.Y.
登録日2017-09-29
公開日2017-12-27
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
5DJ7
DownloadVisualize
BU of 5dj7 by Molmil
S. erythraea trypsin acyl-enzyme
分子名称: Trypsin
著者Blankenship, E, Lodowski, D.T.
登録日2015-09-01
公開日2017-03-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (0.87 Å)
主引用文献High resolution structures of S. erythraeus trypsin throughout the catalytic cycle
To be Published
5DKM
DownloadVisualize
BU of 5dkm by Molmil
S. erythraea trypsin Michaelis-Menten complex
分子名称: Trypsin
著者Blankenship, E, Lodowski, D.T.
登録日2015-09-03
公開日2017-03-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (0.92 Å)
主引用文献High resolution structures of S. erythraeus trypsin throughout the catalytic cycle
To be Published
5DK1
DownloadVisualize
BU of 5dk1 by Molmil
S. erythraea trypsin mixed catalytic intermediate
分子名称: Trypsin
著者Blankenship, E, Lodowski, D.T.
登録日2015-09-02
公開日2017-03-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (0.938 Å)
主引用文献High resolution structures of S. erythraeus trypsin throughout the catalytic cycle
To be Published
3KVC
DownloadVisualize
BU of 3kvc by Molmil
Crystal structure of bovine RPE65 at 1.9 angstrom resolution
分子名称: FE (II) ION, Retinoid isomerohydrolase
著者Kiser, P.D, Lodowski, D.T, Golczak, M, Palczewski, K.
登録日2009-11-29
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Importance of membrane structural integrity for RPE65 retinoid isomerization activity.
J.Biol.Chem., 285, 2010
2I35
DownloadVisualize
BU of 2i35 by Molmil
Crystal structure of rhombohedral crystal form of ground-state rhodopsin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, RETINAL, ...
著者Stenkamp, R.E, Le Trong, I, Lodowski, D.T, Salom, D, Palczewski, K.
登録日2006-08-17
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Crystal structure of a photoactivated deprotonated intermediate of rhodopsin.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2I36
DownloadVisualize
BU of 2i36 by Molmil
Crystal structure of trigonal crystal form of ground-state rhodopsin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, Rhodopsin, ...
著者Stenkamp, R.E, Le Trong, I, Lodowski, D.T, Salom, D, Palczewski, K.
登録日2006-08-17
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Crystal structure of a photoactivated deprotonated intermediate of rhodopsin.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2NWC
DownloadVisualize
BU of 2nwc by Molmil
A 3.02 angstrom crystal structure of wild-type apo GroEL in a monoclinic space group
分子名称: 60 kDa chaperonin
著者Kiser, P.D, Lodowski, D.T, Palczewski, K.
登録日2006-11-14
公開日2007-05-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Purification, crystallization and structure determination of native GroEL from Escherichia coli lacking bound potassium ions
Acta Crystallogr.,Sect.F, 63, 2007
6BTH
DownloadVisualize
BU of 6bth by Molmil
Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with 2-arachidonoylglycerol (2-AG)
分子名称: 1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, DI(HYDROXYETHYL)ETHER, Retinol-binding protein 2
著者Silvaroli, J.A, Blaner, W.S, Lodowski, D.T, Golczak, M.
登録日2017-12-06
公開日2018-12-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight.
Sci Adv, 6, 2020
6BTI
DownloadVisualize
BU of 6bti by Molmil
Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with N-arachidonoylethanolamine (AEA)
分子名称: (5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide, DI(HYDROXYETHYL)ETHER, Retinol-binding protein 2
著者Silvaroli, J.A, Blaner, W.S, Lodowski, D.T, Golczak, M.
登録日2017-12-06
公開日2018-12-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight.
Sci Adv, 6, 2020

219869

件を2024-05-15に公開中

PDB statisticsPDBj update infoContact PDBjnumon