1YM7
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![BU of 1ym7 by Molmil](/molmil-images/mine/1ym7) | G Protein-Coupled Receptor Kinase 2 (GRK2) | 分子名称: | Beta-adrenergic receptor kinase 1 | 著者 | Lodowski, D.T, Barnhill, J.F, Pyskadlo, R.M, Ghirlando, R, Sterne-Marr, R, Tesmer, J.J.G. | 登録日 | 2005-01-20 | 公開日 | 2005-07-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | 主引用文献 | The role of Gbetagamma and domain interfaces in the activation of G protein-coupled receptor kinase 2 Biochemistry, 44, 2005
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8UFY
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![BU of 8ufy by Molmil](/molmil-images/mine/8ufy) | High Resolution structure of A. viridans Lactate Oxidase | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, L-lactate oxidase, ... | 著者 | Lodowski, D.T. | 登録日 | 2023-10-05 | 公開日 | 2024-08-14 | 最終更新日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | An engineered lactate oxidase based electrochemical sensor for continuous detection of biomarker lactic acid in human sweat and serum. Heliyon, 10, 2024
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1OMW
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![BU of 1omw by Molmil](/molmil-images/mine/1omw) | Crystal Structure of the complex between G Protein-Coupled Receptor Kinase 2 and Heterotrimeric G Protein beta 1 and gamma 2 subunits | 分子名称: | G-protein coupled receptor kinase 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1 | 著者 | Lodowski, D.T, Pitcher, J.A, Capel, W.D, Lefkowitz, R.J, Tesmer, J.J.G. | 登録日 | 2003-02-26 | 公開日 | 2003-06-03 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Keeping G proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and G-Beta-Gamma Science, 300, 2003
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2ACX
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![BU of 2acx by Molmil](/molmil-images/mine/2acx) | Crystal Structure of G protein coupled receptor kinase 6 bound to AMPPNP | 分子名称: | G protein-coupled receptor kinase 6, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Lodowski, D.T, Tesmer, V.M, Benovic, J.L, Tesmer, J.J. | 登録日 | 2005-07-19 | 公開日 | 2006-04-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Structure of G Protein-coupled Receptor Kinase (GRK)-6 Defines a Second Lineage of GRKs. J.Biol.Chem., 281, 2006
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2I37
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![BU of 2i37 by Molmil](/molmil-images/mine/2i37) | Crystal structure of a photoactivated rhodopsin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Rhodopsin, ... | 著者 | Lodowski, D.T, Stenkamp, R.E, Salom, D, Le Trong, I, Palczewski, K. | 登録日 | 2006-08-17 | 公開日 | 2006-10-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (4.15 Å) | 主引用文献 | Crystal structure of a photoactivated deprotonated intermediate of rhodopsin. Proc.Natl.Acad.Sci.Usa, 103, 2006
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4X1H
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![BU of 4x1h by Molmil](/molmil-images/mine/4x1h) | Opsin/G(alpha) peptide complex stabilized by nonyl-glucoside | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-terminal derived peptide of guanine nucleotide-binding protein G(t) subunit alpha-1, PALMITIC ACID, ... | 著者 | Blankenship, E, Lodowski, D.T. | 登録日 | 2014-11-24 | 公開日 | 2015-11-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | The High-Resolution Structure of Activated Opsin Reveals a Conserved Solvent Network in the Transmembrane Region Essential for Activation. Structure, 23, 2015
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4YEU
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6N1G
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5KWM
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5HI9
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![BU of 5hi9 by Molmil](/molmil-images/mine/5hi9) | Structure of the full-length TRPV2 channel by cryo-electron microscopy | 分子名称: | Transient Receptor Potential Cation Channel Subfamily V Member 2 | 著者 | Huynh, K.W, Cohen, M.R, Jiansen, J, Samanta, A, Lodowski, D.T, Zhou, Z.H, Moiseenkova-Bell, V.Y. | 登録日 | 2016-01-11 | 公開日 | 2016-03-30 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structure of the full-length TRPV2 channel by cryo-EM. Nat Commun, 7, 2016
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3FSN
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![BU of 3fsn by Molmil](/molmil-images/mine/3fsn) | Crystal structure of RPE65 at 2.14 angstrom resolution | 分子名称: | FE (II) ION, Retinal pigment epithelium-specific 65 kDa protein, TETRAETHYLENE GLYCOL | 著者 | Kiser, P.D, Lodowski, D.T, Palczewski, K. | 登録日 | 2009-01-11 | 公開日 | 2009-09-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Crystal structure of native RPE65, the retinoid isomerase of the visual cycle. Proc.Natl.Acad.Sci.USA, 106, 2009
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3CIK
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![BU of 3cik by Molmil](/molmil-images/mine/3cik) | Human GRK2 in Complex with Gbetagamma subunits | 分子名称: | Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Tesmer, J.J.G, Lodowski, D.T. | 登録日 | 2008-03-11 | 公開日 | 2009-02-17 | 最終更新日 | 2012-03-07 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol. J.Med.Chem., 53, 2010
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2NWC
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3KVC
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![BU of 3kvc by Molmil](/molmil-images/mine/3kvc) | Crystal structure of bovine RPE65 at 1.9 angstrom resolution | 分子名称: | FE (II) ION, Retinoid isomerohydrolase | 著者 | Kiser, P.D, Lodowski, D.T, Golczak, M, Palczewski, K. | 登録日 | 2009-11-29 | 公開日 | 2010-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Importance of membrane structural integrity for RPE65 retinoid isomerization activity. J.Biol.Chem., 285, 2010
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4DPZ
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![BU of 4dpz by Molmil](/molmil-images/mine/4dpz) | Crystal structure of human HRASLS2 | 分子名称: | HRAS-like suppressor 2 | 著者 | Kiser, P.D, Golczak, M, Sears, A.E, Lodowski, D.T, Palczewski, K. | 登録日 | 2012-02-14 | 公開日 | 2012-05-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins. J.Biol.Chem., 287, 2012
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4DOT
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![BU of 4dot by Molmil](/molmil-images/mine/4dot) | Crystal structure of human HRASLS3. | 分子名称: | Group XVI phospholipase A2 | 著者 | Kiser, P.D, Golczak, M, Sears, A.E, Lodowski, D.T, Palczewski, K. | 登録日 | 2012-02-10 | 公開日 | 2012-05-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins. J.Biol.Chem., 287, 2012
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4M7G
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![BU of 4m7g by Molmil](/molmil-images/mine/4m7g) | Streptomyces Erythraeus Trypsin | 分子名称: | Trypsin-like protease | 著者 | Blankenship, E, Vukoti, K, Miyagi, M, Lodowski, D.T. | 登録日 | 2013-08-12 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (0.81 Å) | 主引用文献 | Conformational flexibility in the catalytic triad revealed by the high-resolution crystal structure of Streptomyces erythraeus trypsin in an unliganded state. Acta Crystallogr.,Sect.D, 70, 2014
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4OJ2
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6B5V
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![BU of 6b5v by Molmil](/molmil-images/mine/6b5v) | Structure of TRPV5 in complex with econazole | 分子名称: | 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, CALCIUM ION, Transient receptor potential cation channel subfamily V member 5 | 著者 | Hughes, T.E.T, Lodowski, D.T, Huynh, K.W, Yazici, A, del Rosario, J, Kapoor, A, Basak, S, Samanta, A, Chakrapani, S, Zhou, Z.H, Filizola, M, Rohacs, T, Han, S, Moiseenkova-Bell, V.Y. | 登録日 | 2017-09-29 | 公開日 | 2017-12-27 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM. Nat. Struct. Mol. Biol., 25, 2018
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2I35
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![BU of 2i35 by Molmil](/molmil-images/mine/2i35) | Crystal structure of rhombohedral crystal form of ground-state rhodopsin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, RETINAL, ... | 著者 | Stenkamp, R.E, Le Trong, I, Lodowski, D.T, Salom, D, Palczewski, K. | 登録日 | 2006-08-17 | 公開日 | 2006-10-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Crystal structure of a photoactivated deprotonated intermediate of rhodopsin. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2I36
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![BU of 2i36 by Molmil](/molmil-images/mine/2i36) | Crystal structure of trigonal crystal form of ground-state rhodopsin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, Rhodopsin, ... | 著者 | Stenkamp, R.E, Le Trong, I, Lodowski, D.T, Salom, D, Palczewski, K. | 登録日 | 2006-08-17 | 公開日 | 2006-10-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Crystal structure of a photoactivated deprotonated intermediate of rhodopsin. Proc.Natl.Acad.Sci.Usa, 103, 2006
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5DJ7
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5DKM
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5DK1
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6BTH
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![BU of 6bth by Molmil](/molmil-images/mine/6bth) | Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with 2-arachidonoylglycerol (2-AG) | 分子名称: | 1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, DI(HYDROXYETHYL)ETHER, Retinol-binding protein 2 | 著者 | Silvaroli, J.A, Blaner, W.S, Lodowski, D.T, Golczak, M. | 登録日 | 2017-12-06 | 公開日 | 2018-12-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight. Sci Adv, 6, 2020
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