6OD7
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![BU of 6od7 by Molmil](/molmil-images/mine/6od7) | Herpes simplex virus type 1 (HSV-1) pUL6 portal protein, dodecameric complex | Descriptor: | Portal protein | Authors: | Liu, Y.T, Jih, J, Dai, X.H, Bi, G.Q, Zhou, Z.H. | Deposit date: | 2019-03-26 | Release date: | 2019-06-19 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (5.6 Å) | Cite: | Cryo-EM structures of herpes simplex virus type 1 portal vertex and packaged genome. Nature, 570, 2019
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7LJ3
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![BU of 7lj3 by Molmil](/molmil-images/mine/7lj3) | Structure of human transfer RNA visualized in the cytomegalovirus, a DNA virus | Descriptor: | RNA (75-MER), Tegument protein pp150 | Authors: | Liu, Y.T, Strugatsky, D, Liu, W, Zhou, Z.H. | Deposit date: | 2021-01-28 | Release date: | 2021-11-17 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150. Nat Commun, 12, 2021
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7LIV
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![BU of 7liv by Molmil](/molmil-images/mine/7liv) | Structure of human transfer RNA visualized in the cytomegalovirus, a DNA virus | Descriptor: | Major capsid protein, Small capsomere-interacting protein, Tegument protein pp150, ... | Authors: | Liu, Y.T, Strugatsky, D, Liu, W, Zhou, Z.H. | Deposit date: | 2021-01-28 | Release date: | 2021-09-15 | Last modified: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150. Nat Commun, 12, 2021
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6ODM
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![BU of 6odm by Molmil](/molmil-images/mine/6odm) | Herpes simplex virus type 1 (HSV-1) portal vertex-adjacent capsid/CATC, asymmetric unit | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | Authors: | Liu, Y.T, Jih, J, Dai, X.H, Bi, G.Q, Zhou, Z.H. | Deposit date: | 2019-03-26 | Release date: | 2019-06-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Cryo-EM structures of herpes simplex virus type 1 portal vertex and packaged genome. Nature, 570, 2019
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3PZ7
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![BU of 3pz7 by Molmil](/molmil-images/mine/3pz7) | |
6PPB
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![BU of 6ppb by Molmil](/molmil-images/mine/6ppb) | Kaposi's sarcoma-associated herpesvirus (KSHV), C5 portal vertex structure | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | Authors: | Gong, D, Dai, X, Jih, J, Liu, Y.T, Bi, G.Q, Sun, R, Zhou, Z.H. | Deposit date: | 2019-07-06 | Release date: | 2019-09-11 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV. Cell, 178, 2019
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6PPI
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![BU of 6ppi by Molmil](/molmil-images/mine/6ppi) | Kaposi's sarcoma-associated herpesvirus (KSHV), C12 portal dodecamer structure | Descriptor: | Portal protein | Authors: | Gong, D, Dai, X, Jih, J, Liu, Y.T, Bi, G.Q, Sun, R, Zhou, Z.H. | Deposit date: | 2019-07-07 | Release date: | 2019-09-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV. Cell, 178, 2019
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6PPH
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![BU of 6pph by Molmil](/molmil-images/mine/6pph) | Kaposi's sarcoma-associated herpesvirus (KSHV), C1 penton vertex register, CATC-binding structure | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | Authors: | Gong, D, Dai, X, Jih, J, Liu, Y.T, Bi, G.Q, Sun, R, Zhou, Z.H. | Deposit date: | 2019-07-06 | Release date: | 2019-09-11 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV. Cell, 178, 2019
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6PPD
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![BU of 6ppd by Molmil](/molmil-images/mine/6ppd) | Kaposi's sarcoma-associated herpesvirus (KSHV), C1 penton vertex register, CATC-absent structure | Descriptor: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | Authors: | Gong, D, Dai, X, Jih, J, Liu, Y.T, Bi, G.Q, Sun, R, Zhou, Z.H. | Deposit date: | 2019-07-06 | Release date: | 2019-09-11 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV. Cell, 178, 2019
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8TES
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![BU of 8tes by Molmil](/molmil-images/mine/8tes) | Human cytomegalovirus portal vertex, virion configuration 2 (VC2) | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Large structural phosphoprotein, ... | Authors: | Jih, J, Liu, Y.T, Liu, W, Zhou, H. | Deposit date: | 2023-07-06 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | The incredible bulk: Human cytomegalovirus tegument architectures uncovered by AI-empowered cryo-EM. Sci Adv, 10, 2024
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8TET
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![BU of 8tet by Molmil](/molmil-images/mine/8tet) | Human cytomegalovirus portal vertex, non-infectious enveloped particle (NIEP) configuration 1 (NC1) | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Large structural phosphoprotein, ... | Authors: | Jih, J, Liu, Y.T, Liu, W, Zhou, H. | Deposit date: | 2023-07-07 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.26 Å) | Cite: | The incredible bulk: Human cytomegalovirus tegument architectures uncovered by AI-empowered cryo-EM. Sci Adv, 10, 2024
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8TEP
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![BU of 8tep by Molmil](/molmil-images/mine/8tep) | Human cytomegalovirus portal vertex, virion configuration 1 (VC1) | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Inner tegument protein, ... | Authors: | Jih, J, Liu, Y.T, Liu, W, Zhou, H. | Deposit date: | 2023-07-06 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The incredible bulk: Human cytomegalovirus tegument architectures uncovered by AI-empowered cryo-EM. Sci Adv, 10, 2024
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8TEU
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![BU of 8teu by Molmil](/molmil-images/mine/8teu) | Human cytomegalovirus portal vertex, non-infectious enveloped particle (NIEP) configuration 2 - inverted (NC2-inv) | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Large structural phosphoprotein, ... | Authors: | Jih, J, Liu, Y.T, Liu, W, Zhou, H. | Deposit date: | 2023-07-07 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.01 Å) | Cite: | The incredible bulk: Human cytomegalovirus tegument architectures uncovered by AI-empowered cryo-EM. Sci Adv, 10, 2024
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8TEW
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![BU of 8tew by Molmil](/molmil-images/mine/8tew) | Human cytomegalovirus penton vertex, CVSC-bound configuration | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Large structural phosphoprotein, ... | Authors: | Jih, J, Liu, Y.T, Liu, W, Zhou, H. | Deposit date: | 2023-07-07 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | The incredible bulk: Human cytomegalovirus tegument architectures uncovered by AI-empowered cryo-EM. Sci Adv, 10, 2024
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2OC8
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![BU of 2oc8 by Molmil](/molmil-images/mine/2oc8) | Structure of Hepatitis C Viral NS3 protease domain complexed with NS4A peptide and ketoamide SCH503034 | Descriptor: | BETA-MERCAPTOETHANOL, Hepatitis C virus, ZINC ION, ... | Authors: | Prongay, A.J, Guo, Z, Yao, N, Fischmann, T, Strickland, C, Myers, J, Weber, P.C, Malcolm, B, Beyer, B.M, Ingram, R, Pichardo, J, Hong, Z, Prosise, W.W, Ramanathan, L, Taremi, S.S, Yarosh-Tomaine, T, Zhang, R, Senior, M, Yang, R.S, Arasappan, A, Bennett, F, Bogen, S.L, Chen, K, Jao, E, Liu, Y.T, Lovey, R.G, Saksena, A.K, Venkatraman, S, Girijavallabhan, V, Njoroge, F.G, Madison, V. | Deposit date: | 2006-12-20 | Release date: | 2007-07-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization. J.Med.Chem., 50, 2007
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8WWP
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![BU of 8wwp by Molmil](/molmil-images/mine/8wwp) | PNPase mutant of Mycobacterium tuberculosis | Descriptor: | Bifunctional guanosine pentaphosphate synthetase/polyribonucleotide nucleotidyltransferase | Authors: | Wang, N, Sheng, Y.N, Liu, Y.T. | Deposit date: | 2023-10-26 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Cryo-EM structures of Mycobacterium tuberculosis polynucleotide phosphorylase suggest a potential mechanism for its RNA substrate degradation. Arch.Biochem.Biophys., 754, 2024
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8WXF
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![BU of 8wxf by Molmil](/molmil-images/mine/8wxf) | PNPase of Mycobacterium tuberculosis | Descriptor: | Bifunctional guanosine pentaphosphate synthetase/polyribonucleotide nucleotidyltransferase | Authors: | Wang, N, Sheng, Y.N, Liu, Y.T. | Deposit date: | 2023-10-29 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structures of Mycobacterium tuberculosis polynucleotide phosphorylase suggest a potential mechanism for its RNA substrate degradation. Arch.Biochem.Biophys., 754, 2024
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8F3D
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![BU of 8f3d by Molmil](/molmil-images/mine/8f3d) | 3-methylcrotonyl-CoA carboxylase in filament, beta-subunit centered | Descriptor: | 3-methylcrotonyl-CoA carboxylase alpha-subunit, 3-methylcrotonyl-CoA carboxylase beta-subunit, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL | Authors: | Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H. | Deposit date: | 2022-11-09 | Release date: | 2023-01-11 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase. Structure, 31, 2023
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2A4G
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![BU of 2a4g by Molmil](/molmil-images/mine/2a4g) | Hepatitis C Protease NS3-4A serine protease with Ketoamide Inhibitor SCH225724 Bound | Descriptor: | ({1-[1-CARBAMOYL-PHENYL-METHYL)-CARBAMOYL]-METHYL}-AMINOOXALYL)-BUTYLCARBAMOYL)-3-METHYL-BUTYLCARBAMOYL)-CYCLOHEXYL-METHYL)-CARBAMIC ACID ISOBUTYL ESTER, NS3 protease/helicase, NS4a peptide, ... | Authors: | Arasappan, A, Njoroge, F.G, Chan, T.Y, Bennett, F, Bogen, S.L, Chen, K, Gu, H, Hong, L, Jao, E, Liu, Y.T, Lovey, R.G, Parekh, T, Pike, R.E, Pinto, P, Santhanam, B, Venkatraman, S, Vaccaro, H, Wang, H, Yang, X, Zhu, Z, Mckittrick, B, Saksena, A.K, Girijavallabhan, V, Pichardo, J, Butkiewicz, N, Ingram, R, Malcolm, B, Prongay, A.J, Yao, N, Marten, B, Madison, V, Kemp, S, Levy, O, Lim-Wilby, M, Tamura, S, Ganguly, A.K. | Deposit date: | 2005-06-28 | Release date: | 2006-07-04 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Hepatitis C virus NS3-4a serine protease inhibitors. SAR of P2' moiety with improved potency. Bioorg.Med.Chem.Lett., 15, 2005
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4QSG
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![BU of 4qsg by Molmil](/molmil-images/mine/4qsg) | Crystal structure of gas vesicle protein GvpF from Microcystis aeruginosa | Descriptor: | Gas vesicle protein | Authors: | Xu, B.Y, Dai, Y.N, Zhou, K, Ren, Y.M, Liu, Y.T, Chen, Y, Zhou, C.Z. | Deposit date: | 2014-07-03 | Release date: | 2014-11-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the gas vesicle protein GvpF from the cyanobacterium Microcystis aeruginosa. Acta Crystallogr.,Sect.D, 70, 2014
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3GEN
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![BU of 3gen by Molmil](/molmil-images/mine/3gen) | The 1.6 A crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound | Descriptor: | 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane, Tyrosine-protein kinase BTK | Authors: | Marcotte, D.J, Liu, Y.T, Arduini, R.M, Hession, C.A, Miatkowski, K, Wildes, C.P, Cullen, P.F, Hopkins, B, Mertsching, E, Jenkins, T.J, Romanowski, M.J, Baker, D.P, Silvian, L.F. | Deposit date: | 2009-02-25 | Release date: | 2010-01-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases. Protein Sci., 19, 2010
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8F41
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![BU of 8f41 by Molmil](/molmil-images/mine/8f41) | 3-methylcrotonyl-CoA carboxylase in filament, alpha-subunit centered | Descriptor: | 3-methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit, ... | Authors: | Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H. | Deposit date: | 2022-11-10 | Release date: | 2023-01-11 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase. Structure, 31, 2023
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8SGZ
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![BU of 8sgz by Molmil](/molmil-images/mine/8sgz) | Leishmania tarentolae propionyl-CoA carboxylase (alpha-6-beta-6) | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ... | Authors: | Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. | Deposit date: | 2023-04-13 | Release date: | 2023-05-17 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics. J Struct Biol X, 7, 2023
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8SGX
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![BU of 8sgx by Molmil](/molmil-images/mine/8sgx) | Leishmania tarentolae propionyl-CoA carboxylase (alpha-4-beta-6) | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ... | Authors: | Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. | Deposit date: | 2023-04-13 | Release date: | 2023-05-17 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (10.3 Å) | Cite: | CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics. J Struct Biol X, 7, 2023
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8SGY
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![BU of 8sgy by Molmil](/molmil-images/mine/8sgy) | Leishmania tarentolae propionyl-CoA carboxylase (alpha-5-beta-6) | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ... | Authors: | Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. | Deposit date: | 2023-04-13 | Release date: | 2023-05-17 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (8.62 Å) | Cite: | CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics. J Struct Biol X, 7, 2023
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