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PDB: 656 results

6NWK
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Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with dexamethasone and PGC1a coregulator fragment
Descriptor: ACETYL GROUP, DEXAMETHASONE, DIMETHYL SULFOXIDE, ...
Authors:Liu, X, Ortlund, E.A.
Deposit date:2019-02-06
Release date:2019-10-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain-Peroxisome Proliferator-ActivatedgammaCoactivator 1-alphaComplex with Endogenous and Synthetic Glucocorticoids.
Mol.Pharmacol., 96, 2019
3WMJ
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BU of 3wmj by Molmil
Crystal structure of EIAV vaccine gp45
Descriptor: EIAV vaccine gp45
Authors:Liu, X, Du, J, Qiao, W.
Deposit date:2013-11-19
Release date:2014-11-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:A mutation associated with EIAV vaccine strain within heptad repeat of EIAV gp45 provides insight into vaccine development for HIV
To be Published
3WMI
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BU of 3wmi by Molmil
Crystal structure of EIAV wild type gp45
Descriptor: EIAV gp45 wild type
Authors:Liu, X, Du, J, Qiao, W.
Deposit date:2013-11-19
Release date:2014-11-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A mutation associated with EIAV vaccine strain within heptad repeat of EIAV gp45 provides insight into vaccine development for HIV
To be Published
4GQ2
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BU of 4gq2 by Molmil
S. pombe Nup120-Nup37 complex
Descriptor: Nucleoporin nup120, Nup37
Authors:Liu, X, Mitchell, J, Wozniak, R, Blobel, G, Fan, J.
Deposit date:2012-08-22
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural evolution of the membrane-coating module of the nuclear pore complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
6N48
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Structure of beta2 adrenergic receptor bound to BI167107, Nanobody 6B9, and a positive allosteric modulator
Descriptor: (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Camelid Antibody Fragment, ...
Authors:Liu, X, Masoudi, A, Kahsai, A.W, Huang, L.Y, Pani, B, Hirata, K, Ahn, S, Lefkowitz, R.J, Kobilka, B.K.
Deposit date:2018-11-17
Release date:2019-06-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Mechanism of beta2AR regulation by an intracellular positive allosteric modulator.
Science, 364, 2019
8Z1R
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BU of 8z1r by Molmil
isocitrate lyase MoMcl1
Descriptor: 1,2-ETHANEDIOL, Isocitrate lyase, MAGNESIUM ION
Authors:Liu, X.H, Zhao, W.H.
Deposit date:2024-04-11
Release date:2024-07-03
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:High-resolution crystal structure of the MoMcl1 protein
To Be Published
4GVD
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BU of 4gvd by Molmil
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with Syndecan1 Peptide
Descriptor: 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), CHLORIDE ION, SODIUM ION, ...
Authors:Liu, X, Shepherd, T.R, Murray, A.M, Xu, Z, Fuentes, E.J.
Deposit date:2012-08-30
Release date:2013-03-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics.
Structure, 21, 2013
4GQ1
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Nup37 of S. pombe
Descriptor: Nup37, SULFATE ION
Authors:Liu, X, Mitchell, J, Wozniak, R, Blobel, G, Fan, J.
Deposit date:2012-08-22
Release date:2012-10-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural evolution of the membrane-coating module of the nuclear pore complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
6AHZ
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BU of 6ahz by Molmil
The NMR Structure of the Polysialyltranseferase Domain (PSTD) in Polysialyltransferase ST8siaIV
Descriptor: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase
Authors:Liu, X.H, Lu, B, Peng, L.X, Liao, S.M, Zhou, F, Chen, D, Lu, Z.L, Zhou, G.P, Huang, R.B.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The Inhibition of Polysialyltranseferase ST8SiaIV Through Heparin Binding to Polysialyltransferase Domain (PSTD).
Med Chem, 15, 2019
4GVC
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BU of 4gvc by Molmil
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with phosphorylated Syndecan1 Peptide
Descriptor: 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), CHLORIDE ION, SODIUM ION, ...
Authors:Liu, X, Shepherd, T.R, Murray, A.M, Xu, Z, Fuentes, E.J.
Deposit date:2012-08-30
Release date:2013-03-13
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics.
Structure, 21, 2013
3TGV
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BU of 3tgv by Molmil
Crystal structure of HutZ,the heme storsge protein from Vibrio cholerae
Descriptor: BENZOIC ACID, Heme-binding protein HutZ
Authors:Liu, X, Gong, J, Wang, Z, Du, Q, Wei, T, Zhu, D, Huang, Y, Xu, S, Gu, L.
Deposit date:2011-08-17
Release date:2012-08-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Crystal structure of HutZ,the heme storsge protein from Vibrio cholerae
To be Published
4QBA
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BU of 4qba by Molmil
Crystal structure of the effector-binding domain of S. aureus CcpE
Descriptor: CHLORIDE ION, LysR family regulatory protein
Authors:Liu, X, Lan, L, Yang, C.G.
Deposit date:2014-05-06
Release date:2014-11-19
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Metabolic sensor governing bacterial virulence in Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 111, 2014
8HN1
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BU of 8hn1 by Molmil
Cryo-EM structure of AdTx1-alpha1AAR-Nb6
Descriptor: Alpha-1A adrenergic receptor, Nb6, Toxin AdTx1
Authors:Liu, X, Shi, M.
Deposit date:2022-12-06
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM structure of AdTx1-alpha1AAR-Nb6
To Be Published
7EE5
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BU of 7ee5 by Molmil
Crystal structure of Neu5Gc bound PltC
Descriptor: N-glycolyl-alpha-neuraminic acid, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, Subtilase cytotoxin subunit B-like protein, ...
Authors:Liu, X.Y, Chen, Z, Gao, X.
Deposit date:2021-03-17
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin.
Mbio, 13, 2022
7EE4
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BU of 7ee4 by Molmil
Crystal structure of Neu5Ac bound PltC
Descriptor: N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, ...
Authors:Liu, X.Y, Chen, Z, Gao, X.
Deposit date:2021-03-17
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin.
Mbio, 13, 2022
7EE6
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BU of 7ee6 by Molmil
Crystal structure of PltC toxin
Descriptor: ACETONE, CITRATE ANION, Cytolethal distending toxin subunit B family protein, ...
Authors:Liu, X.Y, Chen, Z, Gao, X.
Deposit date:2021-03-17
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin.
Mbio, 13, 2022
7EE3
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BU of 7ee3 by Molmil
Crystal structure of PltC
Descriptor: Subtilase cytotoxin subunit B-like protein, TETRAETHYLENE GLYCOL
Authors:Liu, X.Y, Chen, Z, Gao, X.
Deposit date:2021-03-17
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin.
Mbio, 13, 2022
6L1Y
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BU of 6l1y by Molmil
structure of gp120/CD4 with a non-canonical surface
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, T-cell surface glycoprotein CD4, ...
Authors:Liu, X, Ning, W.
Deposit date:2019-10-01
Release date:2020-05-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.469 Å)
Cite:A non-canonical binding interface in the crystal structure of HIV-1 gp120 core in complex with CD4.
Sci Rep, 7, 2017
4NXQ
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BU of 4nxq by Molmil
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) in Complex With Caspr4 Peptide
Descriptor: Contactin-associated protein-like 4 peptide, T-lymphoma invasion and metastasis-inducing protein 1
Authors:Liu, X, Speckhard, D.C, Shepherd, T.R, Hengel, S.R, Fuentes, E.J.
Deposit date:2013-12-09
Release date:2015-05-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions.
Structure, 24, 2016
7E5X
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BU of 7e5x by Molmil
THE CRYSTAL STRUCTURE OF COVID-19 MAIN PROTEASE apo form at 2.2 angstrom
Descriptor: 3C-like proteinase
Authors:Liu, X, Zhao, Y, Yang, H, Rao, Z.
Deposit date:2021-02-21
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022
4NXP
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Crystal Structure of Free T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM)
Descriptor: T-lymphoma invasion and metastasis-inducing protein 1
Authors:Liu, X, Speckhard, D.C, Shepherd, T.R, Hengel, S.R, Fuentes, E.J.
Deposit date:2013-12-09
Release date:2015-05-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions.
Structure, 24, 2016
4NXR
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BU of 4nxr by Molmil
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) in Complex With Neurexin-1 Peptide
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), Neurexin-2-beta Peptide, ...
Authors:Liu, X, Speckhard, D.C, Shepherd, T.R, Hengel, S.R, Fuentes, E.J.
Deposit date:2013-12-09
Release date:2015-05-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions.
Structure, 24, 2016
6KPT
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BU of 6kpt by Molmil
Crystal Structure of Acyl-CoA Dehydrogenase FadE5 from Mycobacteria smegmatis
Descriptor: Acyl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Liu, X, Chen, X.B.
Deposit date:2019-08-16
Release date:2020-07-01
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.963 Å)
Cite:Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria.
Proc.Natl.Acad.Sci.USA, 117, 2020
2LCW
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solution structure of FUS/TLS RRM domain
Descriptor: RNA-binding protein FUS
Authors:Liu, X, Ren, J, Niu, C, Gong, W, Feng, W.
Deposit date:2011-05-10
Release date:2012-06-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:TLS-RRM is a promiscuous nucleic acid binding domain
To be Published
6JC0
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Structural analysis of molybdopterin synthases from two mycobacteria pathogens
Descriptor: Putative molybdenum cofactor biosynthesis protein, Putative molybdenum cofactor biosynthesis protein D2 (MoaD2) / thiamine S
Authors:Liu, X, Wang, H.Y.
Deposit date:2019-01-27
Release date:2019-02-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of molybdopterin synthases from two mycobacterial pathogens.
Biochem. Biophys. Res. Commun., 511, 2019

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