6LMJ
| ASFV pA104R in complex with double-strand DNA | Descriptor: | A104R, DNA (5'-D(*TP*GP*CP*TP*TP*AP*TP*CP*AP*AP*TP*TP*TP*GP*TP*TP*GP*CP*A)-3') | Authors: | Wang, H, Qi, J, Chai, Y, Gao, F, Liu, R. | Deposit date: | 2019-12-25 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The structural basis of African swine fever virus pA104R binding to DNA and its inhibition by stilbene derivatives. Proc.Natl.Acad.Sci.USA, 117, 2020
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6JYV
| Structure of an isopenicillin N synthase from Pseudomonas aeruginosa PAO1 | Descriptor: | Probable iron/ascorbate oxidoreductase, SODIUM ION | Authors: | Hao, Z, Che, S, Wang, R, Liu, R, Zhang, Q, Bartlam, M. | Deposit date: | 2019-04-28 | Release date: | 2019-05-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.651 Å) | Cite: | Structural characterization of an isopenicillin N synthase family oxygenase from Pseudomonas aeruginosa PAO1. Biochem.Biophys.Res.Commun., 514, 2019
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4DE6
| Horse spleen apo-ferritin complex with arachidonic acid | Descriptor: | ARACHIDONIC ACID, CADMIUM ION, Ferritin light chain, ... | Authors: | Bu, W, Liu, R, Dmochowski, I.J, Loll, P.J, Eckenhoff, R.G. | Deposit date: | 2012-01-19 | Release date: | 2012-03-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Ferritin couples iron and fatty acid metabolism. Faseb J., 26, 2012
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4H48
| 1.45 angstrom CyPet Structure at pH7.0 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Green fluorescent protein | Authors: | Hu, X.-J, Liu, R. | Deposit date: | 2012-09-17 | Release date: | 2013-09-18 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure insight of the fluorescent state of CyPet To be Published
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4H47
| 1.9 angstrom CyPet structure at pH5.2 | Descriptor: | ACETATE ION, Green fluorescent protein, SULFATE ION | Authors: | Hu, X.-J, Liu, R. | Deposit date: | 2012-09-17 | Release date: | 2013-09-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights of the fluorescent states of CyPet To be Published
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2F9V
| HCV NS3 protease domain with NS4a peptide and a ketoamide inhibitor with P1 and P2 cyclopropylalannines | Descriptor: | (2S,8R,9S,15S)-15-CYCLOHEXYL-9,12-BIS(CYCLOPROPYLMETHYL)-8-HYDROXY-20-METHYL-4,7,11,14,17-PENTAOXO-2-PHENYL-18-OXA-3,6,10,12,13,16-HEXAAZAHENICOSAN-1-OIC ACID, NS3 protease/helicase, ZINC ION, ... | Authors: | Bogen, S.L, Ruan, S, Liu, R, Agrawal, S, Pichardo, J, Prongay, A, Baroudy, B, Saksena, A, Girijavallabhan, V, Njoroge, F.G. | Deposit date: | 2005-12-06 | Release date: | 2007-01-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Depeptidization efforts on P3-P2 a-ketoamide inhibitors of HCV NS3-4A serine protease: Effect on HCV replicon activity. Bioorg.Med.Chem.Lett., 16, 2006
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3RAV
| Horse spleen apo-ferritin with bound Pentobarbital | Descriptor: | 5-ethyl-5-[(2S)-pentan-2-yl]pyrimidine-2,4,6(1H,3H,5H)-trione, CADMIUM ION, Ferritin light chain, ... | Authors: | Oakley, S.H, Vedula, L.S, Xi, J, Liu, R, Eckenhoff, R.G, Loll, P.J. | Deposit date: | 2011-03-28 | Release date: | 2011-05-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High resolution view of barbiturate recognition by a protein binding site to be published
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3RD0
| Horse spleen apo-ferritin with bound thiopental | Descriptor: | 5-ethyl-5-[(2R)-pentan-2-yl]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione, CADMIUM ION, Ferritin light chain, ... | Authors: | Oakley, S.H, Vedula, L.S, Xi, J, Liu, R, Eckenhoff, R.G, Loll, P.J. | Deposit date: | 2011-03-31 | Release date: | 2011-05-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | High resolution view of barbiturate recognition by a protein binding site to be published
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6JT2
| Structure of human soluble guanylate cyclase in the NO activated state | Descriptor: | Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, MAGNESIUM ION, ... | Authors: | Chen, L, Kang, Y, Liu, R, Wu, J.-X. | Deposit date: | 2019-04-08 | Release date: | 2019-09-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural insights into the mechanism of human soluble guanylate cyclase. Nature, 574, 2019
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6JT0
| Structure of human soluble guanylate cyclase in the unliganded state | Descriptor: | Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Chen, L, Kang, Y, Liu, R, Wu, J.-X. | Deposit date: | 2019-04-08 | Release date: | 2019-08-28 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural insights into the mechanism of human soluble guanylate cyclase. Nature, 574, 2019
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6JT1
| Structure of human soluble guanylate cyclase in the heme oxidised state | Descriptor: | Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Chen, L, Kang, Y, Liu, R, Wu, J.-X. | Deposit date: | 2019-04-08 | Release date: | 2019-08-28 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural insights into the mechanism of human soluble guanylate cyclase. Nature, 574, 2019
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7D9R
| Structure of huamn soluble guanylate cyclase in the riociguat and NO-bound state | Descriptor: | Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, MAGNESIUM ION, ... | Authors: | Chen, L, Liu, R, Kang, Y. | Deposit date: | 2020-10-14 | Release date: | 2021-08-11 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Activation mechanism of human soluble guanylate cyclase by stimulators and activators. Nat Commun, 12, 2021
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7D9U
| Structure of human soluble guanylate cyclase in the cinciguat-bound activated state | Descriptor: | 4-({(4-carboxybutyl)[2-(2-{[4-(2-phenylethyl)benzyl]oxy}phenyl)ethyl]amino}methyl)benzoic acid, Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, ... | Authors: | Chen, L, Liu, R, Kang, Y. | Deposit date: | 2020-10-14 | Release date: | 2021-08-11 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Activation mechanism of human soluble guanylate cyclase by stimulators and activators. Nat Commun, 12, 2021
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7D9S
| Structure of huamn soluble guanylate cyclase in the YC1 and NO-bound state | Descriptor: | Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, MAGNESIUM ION, ... | Authors: | Chen, L, Liu, R, Kang, Y. | Deposit date: | 2020-10-14 | Release date: | 2021-08-11 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Activation mechanism of human soluble guanylate cyclase by stimulators and activators. Nat Commun, 12, 2021
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7D9T
| Structure of human soluble guanylate cyclase in the cinciguat-bound inactive state | Descriptor: | 4-({(4-carboxybutyl)[2-(2-{[4-(2-phenylethyl)benzyl]oxy}phenyl)ethyl]amino}methyl)benzoic acid, Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1 | Authors: | Chen, L, Liu, R, Kang, Y. | Deposit date: | 2020-10-14 | Release date: | 2021-08-11 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Activation mechanism of human soluble guanylate cyclase by stimulators and activators. Nat Commun, 12, 2021
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8HBE
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8HBF
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8HBH
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8GZ3
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7VSI
| Structure of human SGLT2-MAP17 complex bound with empagliflozin | Descriptor: | (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol, PALMITIC ACID, PDZK1-interacting protein 1, ... | Authors: | Chen, L, Niu, Y, Liu, R. | Deposit date: | 2021-10-26 | Release date: | 2021-12-15 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structural basis of inhibition of the human SGLT2-MAP17 glucose transporter. Nature, 601, 2022
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7VSP
| Crystal strcuture of the tandem B-Box domains of COL2 | Descriptor: | ZINC ION, Zinc finger protein CONSTANS-LIKE 2 | Authors: | Lv, X, Liu, R, Du, J. | Deposit date: | 2021-10-27 | Release date: | 2022-03-02 | Last modified: | 2022-03-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis of CONSTANS oligomerization in FLOWERING LOCUS T activation. J Integr Plant Biol, 64, 2022
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7XQV
| The complex of nanobody Rh57 binding to GTP-bound RhoA active form | Descriptor: | ALANINE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Zhang, Y.R, Liu, R, Ding, Y. | Deposit date: | 2022-05-09 | Release date: | 2022-07-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Structural insights into the binding of nanobody Rh57 to active RhoA-GTP. Biochem.Biophys.Res.Commun., 616, 2022
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1PFM
| PF4-M2 CHIMERIC MUTANT WITH THE FIRST 10 N-TERMINAL RESIDUES OF R-PF4 REPLACED BY THE N-TERMINAL RESIDUES OF THE IL8 SEQUENCE. MODELS 1-15 OF A 27-MODEL SET. | Descriptor: | PF4-M2 CHIMERA | Authors: | Mayo, K.H, Roongta, V, Ilyina, E, Milius, R, Barker, S, Quinlan, C, La Rosa, G, Daly, T.J. | Deposit date: | 1995-07-18 | Release date: | 1996-01-29 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | NMR solution structure of the 32-kDa platelet factor 4 ELR-motif N-terminal chimera: a symmetric tetramer. Biochemistry, 34, 1995
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1PFN
| PF4-M2 CHIMERIC MUTANT WITH THE FIRST 10 N-TERMINAL RESIDUES OF R-PF4 REPLACED BY THE N-TERMINAL RESIDUES OF THE IL8 SEQUENCE. MODELS 16-27 OF A 27-MODEL SET. | Descriptor: | PF4-M2 CHIMERA | Authors: | Mayo, K.H, Roongta, V, Ilyina, E, Milius, R, Barker, S, Quinlan, C, La Rosa, G, Daly, T.J. | Deposit date: | 1995-07-18 | Release date: | 1996-01-29 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | NMR solution structure of the 32-kDa platelet factor 4 ELR-motif N-terminal chimera: a symmetric tetramer. Biochemistry, 34, 1995
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