7D9U
Structure of human soluble guanylate cyclase in the cinciguat-bound activated state
Summary for 7D9U
Entry DOI | 10.2210/pdb7d9u/pdb |
EMDB information | 30621 |
Descriptor | Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... (5 entities in total) |
Functional Keywords | soluble guanylate cyclase, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 149301.32 |
Authors | |
Primary citation | Liu, R.,Kang, Y.,Chen, L. Activation mechanism of human soluble guanylate cyclase by stimulators and activators. Nat Commun, 12:5492-5492, 2021 Cited by PubMed: 34535643DOI: 10.1038/s41467-021-25617-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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