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PDB: 837 件

2OS6
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Solution structure of LARG PDZ domain in complex with C-terminal octa-peptide of Plexin B1
分子名称: C-terminal peptide of Plexin-B1, Rho guanine nucleotide exchange factor 12
著者Liu, J, Huang, H, Yang, Y.
登録日2007-02-05
公開日2008-02-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the LARG PDZ domain in complex with C-terminal peptide of Plexin B1
To be Published
2R2V
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BU of 2r2v by Molmil
Sequence Determinants of the Topology of the Lac Repressor Tetrameric Coiled Coil
分子名称: ACETATE ION, CITRIC ACID, GCN4 leucine zipper, ...
著者Liu, J, Lu, M.
登録日2007-08-27
公開日2008-06-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Conformational specificity of the lac repressor coiled-coil tetramerization domain.
Biochemistry, 46, 2007
3R00
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BU of 3r00 by Molmil
The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors
分子名称: 5-bromo-1-benzofuran-2-carboxylic acid, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase pim-1
著者Liu, J.
登録日2011-03-07
公開日2011-05-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
2IPZ
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BU of 2ipz by Molmil
A Parallel Coiled-Coil Tetramer with Offset Helices
分子名称: GLYCEROL, General control protein GCN4, ISOPROPYL ALCOHOL
著者Liu, J, Lu, M.
登録日2006-10-12
公開日2007-01-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A Parallel Coiled-Coil Tetramer with Offset Helices.
Biochemistry, 45, 2006
2IEQ
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BU of 2ieq by Molmil
Core Structure of S2 from the Human Coronavirus NL63 Spike Glycoprotein
分子名称: ACETATE ION, SODIUM ION, Spike glycoprotein
著者Liu, J.
登録日2006-09-19
公開日2007-01-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.747 Å)
主引用文献Core Structure of S2 from the Human Coronavirus NL63 Spike Glycoprotein
Biochemistry, 45, 2006
2HY6
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A seven-helix coiled coil
分子名称: General control protein GCN4, HEXANE-1,6-DIOL
著者Liu, J, Zheng, Q, Deng, Y, Cheng, C.S, Kallenbach, N.R, Lu, M.
登録日2006-08-04
公開日2006-10-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A seven-helix coiled coil.
Proc.Natl.Acad.Sci.Usa, 103, 2006
7E35
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BU of 7e35 by Molmil
Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant bound to compound S43
分子名称: N-[(3-acetamidophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, Non-structural protein 3, ZINC ION
著者Liu, J, Wang, Y, Xu, X, Pan, L.
登録日2021-02-08
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2.
Cell Chem Biol, 28, 2021
5WEH
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BU of 5weh by Molmil
Cytochrome c oxidase from Rhodobacter sphaeroides in the reduced state
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Aa3-type cytochrome c oxidase subunit IV, CALCIUM ION, ...
著者Liu, J, Ferguson-Miller, F, Ling, Q, Hiser, C.
登録日2017-07-10
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Role of conformational change and K-path ligands in controlling cytochrome c oxidase activity.
Biochem. Soc. Trans., 45, 2017
7D6H
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BU of 7d6h by Molmil
Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant
分子名称: PHOSPHATE ION, Papain-like protease, ZINC ION
著者Liu, J, Wang, Y, Pan, L.
登録日2020-09-30
公開日2020-11-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2.
Cell Chem Biol, 28, 2021
3R01
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BU of 3r01 by Molmil
The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors
分子名称: 5-bromo-7-methoxy-1-benzofuran-2-carboxylic acid, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase pim-1
著者Liu, J.
登録日2011-03-07
公開日2011-05-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
2GUV
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BU of 2guv by Molmil
Conformational Transition between Four- and Five-stranded Phenylalanine Zippers Determined by a Local Packing Interaction
分子名称: Major outer membrane lipoprotein
著者Liu, J, Zheng, Q, Deng, Y, Kallenbach, N.R, Lu, M.
登録日2006-05-01
公開日2006-07-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Conformational Transition between Four and Five-stranded Phenylalanine Zippers Determined by a Local Packing Interaction.
J.Mol.Biol., 361, 2006
2GUS
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Conformational Transition between Four- and Five-stranded Phenylalanine Zippers Determined by a Local Packing Interaction
分子名称: Major outer membrane lipoprotein
著者Liu, J, Zheng, Q, Deng, Y, Kallenbach, N.R, Lu, M.
登録日2006-05-01
公開日2006-07-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Conformational Transition between Four and Five-stranded Phenylalanine Zippers Determined by a Local Packing Interaction.
J.Mol.Biol., 361, 2006
7D60
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Cryo-EM Structure of human CALHM5 in the presence of rubidium red
分子名称: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5
著者Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S.
登録日2020-09-28
公開日2020-12-23
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
7D65
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Cryo-EM Structure of human CALHM5 in the presence of Ca2+
分子名称: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5
著者Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S.
登録日2020-09-29
公開日2020-12-23
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
7D61
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Cryo-EM Structure of human CALHM5 in the presence of EDTA
分子名称: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5
著者Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S.
登録日2020-09-28
公開日2020-12-23
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
5X56
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BU of 5x56 by Molmil
Crystal structure of PSB27 from Arabidopsis thaliana
分子名称: Photosystem II repair protein PSB27-H1, chloroplastic
著者Liu, J, Cheng, X.
登録日2017-02-15
公開日2017-12-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of Psb27 from Arabidopsis thaliana determined at a resolution of 1.85 angstrom.
Photosyn. Res., 136, 2018
4QKT
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BU of 4qkt by Molmil
Azurin mutant M121EM44K with copper
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Azurin, ...
著者Liu, J, Robinson, H, Lu, Y.
登録日2014-06-09
公開日2014-08-13
最終更新日2014-10-01
実験手法X-RAY DIFFRACTION (1.641 Å)
主引用文献Redesigning the Blue Copper Azurin into a Redox-Active Mononuclear Nonheme Iron Protein: Preparation and Study of Fe(II)-M121E Azurin.
J.Am.Chem.Soc., 136, 2014
4QLW
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BU of 4qlw by Molmil
Azurin mutant M121E with iron
分子名称: Azurin, FE (III) ION, NITRATE ION, ...
著者Liu, J, Robinson, H, Lu, Y.
登録日2014-06-13
公開日2014-08-13
最終更新日2014-10-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Redesigning the Blue Copper Azurin into a Redox-Active Mononuclear Nonheme Iron Protein: Preparation and Study of Fe(II)-M121E Azurin.
J.Am.Chem.Soc., 136, 2014
7CJB
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BU of 7cjb by Molmil
VHL recognizes hydroxyproline in RIPK1
分子名称: Elongin-B, Elongin-C, GLYCEROL, ...
著者Liu, J, Wang, Y, Pan, L.
登録日2020-07-09
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献VHL recognizes hydroxyproline in RIPK1
To Be Published
7V8E
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Crystal structure of IpaH1.4 LRR domain bound to HOIL-1L UBL domain.
分子名称: RING-type E3 ubiquitin transferase, RanBP-type and C3HC4-type zinc finger-containing protein 1
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-22
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8H
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BU of 7v8h by Molmil
Crystal structure of LRR domain from Shigella flexneri IpaH1.4
分子名称: RING-type E3 ubiquitin transferase
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-23
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8G
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Crystal structure of HOIP RING1 domain bound to IpaH1.4 LRR domain
分子名称: E3 ubiquitin-protein ligase RNF31, RING-type E3 ubiquitin transferase, ZINC ION
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-23
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8F
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Crystal structure of UBE2L3 bound to HOIP RING1 domain.
分子名称: E3 ubiquitin-protein ligase RNF31, Ubiquitin-conjugating enzyme E2 L3, ZINC ION
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-22
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V59
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Cryo-EM structure of spyCas9-sgRNA-DNA dimer
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (49-MER), RNA (115-MER)
著者Liu, J, Deng, P.
登録日2021-08-16
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (5.26 Å)
主引用文献Nonspecific interactions between SpCas9 and dsDNA sites located downstream of the PAM mediate facilitated diffusion to accelerate target search.
Chem Sci, 12, 2021
3TI8
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Crystal structure of influenza A virus neuraminidase N5 complexed with laninamivir
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid, ...
著者Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F.
登録日2011-08-20
公開日2011-11-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011

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