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PDB: 1127 results
4F0I
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BU of 4f0i by Molmil
Crystal structure of apo TrkA
Descriptor: High affinity nerve growth factor receptor
Authors:Liu, J.
Deposit date:2012-05-04
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:The Crystal Structures of TrkA and TrkB Suggest Key Regions for Achieving Selective Inhibition.
J.Mol.Biol., 423, 2012
2LSG
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BU of 2lsg by Molmil
Solution structure of the mouse Rev1 C-terminal domain
Descriptor: DNA repair protein REV1
Authors:Liu, J, Wojtaszek, J, Zhou, P.
Deposit date:2012-04-30
Release date:2012-06-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Multifaceted recognition of vertebrate Rev1 by translesion polymerases zeta and kappa.
J.Biol.Chem., 287, 2012
4GKG
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BU of 4gkg by Molmil
Crystal structure of the S-Helix Linker
Descriptor: C4-dicarboxylate transport sensor protein dctB, PHOSPHATE ION
Authors:Liu, J.W, Lu, D, Sun, Y.J, Wen, J, Yang, Y, Yang, J.G, Wei, X.L, Zhang, X.D, Wang, Y.P.
Deposit date:2012-08-11
Release date:2013-08-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.695 Å)
Cite:Crystal structure of the S-Helix Linker
To be Published
3VBV
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BU of 3vbv by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: 8-hydroxyquinoline-2-carboxamide, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
4F7P
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BU of 4f7p by Molmil
Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009H1N1 PB1 (496-505)
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
Authors:Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, Gao, G.F.
Deposit date:2012-05-16
Release date:2012-10-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
3VBQ
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BU of 3vbq by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: (5~{Z})-5-[[3-[6-[(4-azanylcyclohexyl)amino]pyrazin-2-yl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
4K7A
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BU of 4k7a by Molmil
Crystal structure of the androgen receptor ligand binding domain in complex with minoxidil
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, 6-PIPERIDIN-1-YLPYRIMIDINE-2,4-DIAMINE 3-OXIDE, Androgen receptor
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2013-04-16
Release date:2014-04-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Crystal structure of the androgen receptor ligand binding domain in complex with minoxidil
To be Published
2IEQ
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BU of 2ieq by Molmil
Core Structure of S2 from the Human Coronavirus NL63 Spike Glycoprotein
Descriptor: ACETATE ION, SODIUM ION, Spike glycoprotein
Authors:Liu, J.
Deposit date:2006-09-19
Release date:2007-01-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.747 Å)
Cite:Core Structure of S2 from the Human Coronavirus NL63 Spike Glycoprotein
Biochemistry, 45, 2006
3TCP
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BU of 3tcp by Molmil
Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC569
Descriptor: 1-[(trans-4-aminocyclohexyl)methyl]-N-butyl-3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine, CALCIUM ION, CHLORIDE ION, ...
Authors:Liu, J, Yang, C, Simpson, C, DeRyckere, D, Van Deusen, A, Miley, M, Kireev, D.B, Norris-Drouin, J, Sather, S, Hunter, D, Patel, H.S, Janzen, W.P, Machius, M, Johnson, G, Earp, H.S, Graham, D.K, Frye, S, Wang, X.
Deposit date:2011-08-09
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia.
ACS Med Chem Lett, 3, 2012
3VBY
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BU of 3vby by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: IMIDAZOLE, Serine/threonine-protein kinase pim-1, furan-2-yl(1H-indol-3-yl)methanone
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
2NRN
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BU of 2nrn by Molmil
Self-assembly of coiled-coil tetramers in the 1.40 A structure of a leucine-zipper mutant
Descriptor: General control protein GCN4, PHOSPHATE ION
Authors:Liu, J, Lu, M.
Deposit date:2006-11-02
Release date:2007-04-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Self-assembly of coiled-coil tetramers in the 1.40 A structure of a leucine-zipper mutant.
Protein Sci., 16, 2007
2IPZ
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BU of 2ipz by Molmil
A Parallel Coiled-Coil Tetramer with Offset Helices
Descriptor: GLYCEROL, General control protein GCN4, ISOPROPYL ALCOHOL
Authors:Liu, J, Lu, M.
Deposit date:2006-10-12
Release date:2007-01-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:A Parallel Coiled-Coil Tetramer with Offset Helices.
Biochemistry, 45, 2006
3VBW
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BU of 3vbw by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: 1,3-dioxo-2,3-dihydro-1H-indene-2-carbonitrile, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
4HBK
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BU of 4hbk by Molmil
Structure of the Aldose Reductase from Schistosoma japonicum
Descriptor: Aldo-keto reductase family 1, member B4 (Aldose reductase)
Authors:Liu, J, Cheng, J, Zhang, X, Yang, Z, Hu, W, Xu, Y.
Deposit date:2012-09-28
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Aldose reductase from Schistosoma japonicum: crystallization and structure-based inhibitor screening for discovering antischistosomal lead compounds.
Parasit Vectors, 6, 2013
2MTP
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BU of 2mtp by Molmil
The structure of Filamin repeat 21 bound to integrin
Descriptor: Filamin-A, Integrin alpha-IIb, Integrin beta-3
Authors:Liu, J, Qin, J.
Deposit date:2014-08-28
Release date:2015-04-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural mechanism of integrin inactivation by filamin.
Nat.Struct.Mol.Biol., 22, 2015
4F7M
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BU of 4f7m by Molmil
Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009 H1N1 PA (649-658)
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
Authors:Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, George, F.G.
Deposit date:2012-05-16
Release date:2012-10-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
4FQG
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BU of 4fqg by Molmil
Crystal structure of the TCERG1 FF4-6 tandem repeat domain
Descriptor: CHLORIDE ION, NICKEL (II) ION, Transcription elongation regulator 1
Authors:Liu, J, Fan, S, Lee, C.J, Greenleaf, A.L, Zhou, P.
Deposit date:2012-06-25
Release date:2013-02-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser2, Ser5, and Ser7 within the Carboxyl-terminal Domain Repeat.
J.Biol.Chem., 288, 2013
3UIA
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BU of 3uia by Molmil
Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Glycoprotein 41
Authors:Liu, J, Lu, M.
Deposit date:2011-11-04
Release date:2013-05-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
To be Published
3VBX
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BU of 3vbx by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: 6-bromo-4-hydroxy-2H-chromen-2-one, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
3VC4
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BU of 3vc4 by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: (5Z)-5-[3-(trifluoromethyl)benzylidene]-1,3-thiazolidine-2,4-dione, IMIDAZOLE, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-03
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
3VBT
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BU of 3vbt by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: 4-chloro-2-(1H-pyrazol-3-yl)phenol, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
4F7T
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BU of 4f7t by Molmil
Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009 H1N1 PB1 (498-505)
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
Authors:Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, Gao, G.F.
Deposit date:2012-05-16
Release date:2012-10-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
2L3T
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BU of 2l3t by Molmil
Solution structure of tandem SH2 domain from Spt6
Descriptor: Transcription elongation factor SPT6
Authors:Liu, J, Zhang, J, Wu, J, Shi, Y.
Deposit date:2010-09-22
Release date:2011-06-15
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the tandem SH2 domains from Spt6 and their binding to the phosphorylated RNA polymerase II C-terminal domain
To be Published
2HZ5
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BU of 2hz5 by Molmil
Crystal structure of human dynein light chain Dnlc2A
Descriptor: CESIUM ION, Dynein light chain 2A, cytoplasmic
Authors:Liu, J.-F, Wang, Z.-X, Wang, X.-Q, Tang, Q, An, X.-M, Gui, L.-L, Liang, D.-C.
Deposit date:2006-08-08
Release date:2007-08-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human dynein light chain Dnlc2A: Structural insights into the interaction with IC74
Biochem.Biophys.Res.Commun., 349, 2006
2HY6
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BU of 2hy6 by Molmil
A seven-helix coiled coil
Descriptor: General control protein GCN4, HEXANE-1,6-DIOL
Authors:Liu, J, Zheng, Q, Deng, Y, Cheng, C.S, Kallenbach, N.R, Lu, M.
Deposit date:2006-08-04
Release date:2006-10-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A seven-helix coiled coil.
Proc.Natl.Acad.Sci.Usa, 103, 2006

226707

數據於2024-10-30公開中

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