4F0I

Crystal structure of apo TrkA

Summary for 4F0I

• Entry DOI: 10.2210/pdb4f0i/pdb
• Descriptor: High affinity nerve growth factor receptor (2 entities in total)
• Functional Keywords: tyrosine kinase, rossmann fold, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Single-pass type I membrane protein: P04629
• Total number of polymer chains: 2
• Total formula weight: 67928.39

Authors

Liu, J. (deposition date: 2012-05-04, release date: 2012-09-05, Last modification date: 2024-02-28)

• Primary citation: Bertrand, T.,Kothe, M.,Liu, J.,Dupuy, A.,Rak, A.,Berne, P.F.,Davis, S.,Gladysheva, T.,Valtre, C.,Crenne, J.Y.,Mathieu, M.; The Crystal Structures of TrkA and TrkB Suggest Key Regions for Achieving Selective Inhibition.; J.Mol.Biol., 423:439-453, 2012; PubMed: 22902478; DOI: 10.1016/j.jmb.2012.08.002

Experimental method

X-RAY DIFFRACTION (2.302 Å)