4F0I
Crystal structure of apo TrkA
Summary for 4F0I
Entry DOI | 10.2210/pdb4f0i/pdb |
Descriptor | High affinity nerve growth factor receptor (2 entities in total) |
Functional Keywords | tyrosine kinase, rossmann fold, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type I membrane protein: P04629 |
Total number of polymer chains | 2 |
Total formula weight | 67928.39 |
Authors | |
Primary citation | Bertrand, T.,Kothe, M.,Liu, J.,Dupuy, A.,Rak, A.,Berne, P.F.,Davis, S.,Gladysheva, T.,Valtre, C.,Crenne, J.Y.,Mathieu, M. The Crystal Structures of TrkA and TrkB Suggest Key Regions for Achieving Selective Inhibition. J.Mol.Biol., 423:439-453, 2012 Cited by PubMed: 22902478DOI: 10.1016/j.jmb.2012.08.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.302 Å) |
Structure validation
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