6F8E
 
 | | PH domain from TgAPH | | 分子名称: | Pleckstrin homology domain | | 著者 | Darvill, N, Liu, B, Matthews, S, Soldati-Favre, D, Rouse, S, Benjamin, S, Blake, T, Dubois, D.J, Hammoudi, P.M, Pino, P. | | 登録日 | 2017-12-13 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis of Phosphatidic Acid Sensing by APH in Apicomplexan Parasites.
Structure, 26, 2018
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4F27
 | | Crystal structures reveal the multi-ligand binding mechanism of the Staphylococcus aureus ClfB | | 分子名称: | Clumping factor B, MAGNESIUM ION, peptide from Fibrinogen alpha chain | | 著者 | Yang, M.J, Xiang, H, Wang, J.W, Liu, B, Chen, Y.G, Liu, L, Deng, X.M, Feng, Y. | | 登録日 | 2012-05-07 | | 公開日 | 2012-08-08 | | 最終更新日 | 2015-02-04 | | 実験手法 | X-RAY DIFFRACTION (1.917 Å) | | 主引用文献 | Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB
Plos Pathog., 8, 2012
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8UUL
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8UUN
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5F5M
 | | Crystal structure of Marburg virus nucleoprotein core domain | | 分子名称: | Nucleoprotein | | 著者 | Guo, Y, Liu, B.C, Liu, X, Li, G.B, Wang, W.M, Dong, S.S, Wang, W.J. | | 登録日 | 2015-12-04 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.902 Å) | | 主引用文献 | Structural Insight into Nucleoprotein Conformation Change Chaperoned by VP35 Peptide in Marburg Virus
J. Virol., 91, 2017
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5O71
 | | Crystal structure of human USP25 | | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 25 | | 著者 | Reverter, D, Liu, B. | | 登録日 | 2017-06-07 | | 公開日 | 2018-06-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.283 Å) | | 主引用文献 | A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25.
Nat Commun, 9, 2018
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4F1Z
 | | Crystal structures reveal the multi-ligand binding mechanism of the Staphylococcus aureus ClfB | | 分子名称: | Clumping factor B, MAGNESIUM ION, peptide from Keratin, ... | | 著者 | Yang, M.J, Xiang, H, Wang, J.W, Liu, B, Chen, Y.G, Liu, L, Deng, X.M, Feng, Y. | | 登録日 | 2012-05-07 | | 公開日 | 2012-08-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB
Plos Pathog., 8, 2012
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4F24
 | | Crystal structures reveal the multi-ligand binding mechanism of the Staphylococcus aureus ClfB | | 分子名称: | Clumping factor B, MAGNESIUM ION | | 著者 | Yang, M.J, Xiang, H, Wang, J.W, Liu, B, Chen, Y.G, Liu, L, Deng, X.M, Feng, Y. | | 登録日 | 2012-05-07 | | 公開日 | 2012-08-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.509 Å) | | 主引用文献 | Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB
Plos Pathog., 8, 2012
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1APL
 | | CRYSTAL STRUCTURE OF A MAT-ALPHA2 HOMEODOMAIN-OPERATOR COMPLEX SUGGESTS A GENERAL MODEL FOR HOMEODOMAIN-DNA INTERACTIONS | | 分子名称: | DNA (5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*CP*AP*TP*TP*TP*AP*C P*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*GP*TP*AP*AP*AP*TP*GP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT-ALPHA2 HOMEODOMAIN) | | 著者 | Wolberger, C, Vershon, A.K, Liu, B, Johnson, A.D, Pabo, C.O. | | 登録日 | 1993-10-04 | | 公開日 | 1993-10-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions.
Cell(Cambridge,Mass.), 67, 1991
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4F20
 | | Crystal structures reveal the multi-ligand binding mechanism of the Staphylococcus aureus ClfB | | 分子名称: | Clumping factor B, MAGNESIUM ION, peptide from Dermokine | | 著者 | Yang, M.J, Xiang, H, Wang, J.W, Liu, B, Chen, Y.G, Liu, L, Deng, X.M, Feng, Y. | | 登録日 | 2012-05-07 | | 公開日 | 2012-08-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | | 主引用文献 | Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB
Plos Pathog., 8, 2012
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3UAF
 | | Crystal Structure of a TTR-52 mutant of C. elegans | | 分子名称: | TTR-52 | | 著者 | Kang, Y.Y, Zhao, D.F, Liang, H.H, Liu, B, Liu, Q.W, Wang, X.C, Liu, Y.F. | | 登録日 | 2011-10-21 | | 公開日 | 2012-10-24 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural study of TTR-52 reveals the mechanism by which a bridging molecule mediates apoptotic cell engulfment
Genes Dev., 26, 2012
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8UUM
 | | Prototypic SARS-CoV-2 spike (containing K417) in the open conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose, ... | | 著者 | Geng, Q, Liu, B, Li, F. | | 登録日 | 2023-11-01 | | 公開日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Lys417 acts as a molecular switch that regulates the conformation of SARS-CoV-2 spike protein.
Elife, 12, 2023
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8UUO
 | | Prototypic SARS-CoV-2 spike (containing V417) in the open conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose, ... | | 著者 | Geng, Q, Liu, B, Li, F. | | 登録日 | 2023-11-01 | | 公開日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Lys417 acts as a molecular switch that regulates the conformation of SARS-CoV-2 spike protein.
Elife, 12, 2023
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7UY5
 | | Tetrahymena telomerase with CST | | 分子名称: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | | 著者 | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | | 登録日 | 2022-05-06 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
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7UY6
 | | Tetrahymena telomerase at 2.9 Angstrom resolution | | 分子名称: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | | 著者 | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | | 登録日 | 2022-05-06 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
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7TGW
 | | Omicron spike at 3.0 A (open form) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Ye, G, Liu, B, Li, F. | | 登録日 | 2022-01-09 | | 公開日 | 2022-03-09 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain.
Nat Commun, 13, 2022
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1STR
 | | STREPTAVIDIN DIMERIZED BY DISULFIDE-BONDED PEPTIDE AC-CHPQNT-NH2 DIMER | | 分子名称: | AC-CHPQNT-NH2, STREPTAVIDIN | | 著者 | Katz, B.A, Cass, R.T, Liu, B, Arze, R, Collins, N. | | 登録日 | 1995-09-12 | | 公開日 | 1996-03-08 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Topochemical catalysis achieved by structure-based ligand design.
J.Biol.Chem., 270, 1995
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1STS
 | | STREPTAVIDIN DIMERIZED BY DISULFIDE-BONDED PEPTIDE FCHPQNT-NH2 DIMER | | 分子名称: | FCHPQNT-NH2, STREPTAVIDIN | | 著者 | Katz, B.A, Cass, R.T, Liu, B, Arze, R, Collins, N. | | 登録日 | 1995-09-12 | | 公開日 | 1996-03-08 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Topochemical catalysis achieved by structure-based ligand design.
J.Biol.Chem., 270, 1995
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5H4D
 | | Crystal structure of hSIRT3 in complex with a specific agonist Amiodarone hydrochloride | | 分子名称: | (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone, 7-AMINO-4-METHYL-CHROMEN-2-ONE, ARG-HIS-LYS, ... | | 著者 | Zhang, S, Fu, L, Liu, J, Liu, B. | | 登録日 | 2016-10-31 | | 公開日 | 2017-11-08 | | 最終更新日 | 2023-04-05 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | Crystal structure of hSIRT3 in complex with a specific agonist Amiodarone hydrochloride
To Be Published
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8HD5
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7TGY
 | | Prototypic SARS-CoV-2 G614 spike (closed form) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Ye, G, Liu, B, Li, F. | | 登録日 | 2022-01-09 | | 公開日 | 2022-03-09 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain.
Nat Commun, 13, 2022
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7TGX
 | | Prototypic SARS-CoV-2 G614 spike (open form) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose, ... | | 著者 | Ye, G, Liu, B, Li, F. | | 登録日 | 2022-01-09 | | 公開日 | 2022-03-09 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain.
Nat Commun, 13, 2022
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4R05
 | | Crystal structure of the refolded DENV3 methyltransferase | | 分子名称: | Nonstructural protein NS5 | | 著者 | Brecher, M.B, Li, Z, Zhang, J, Chen, H, Lin, Q, Liu, B, Li, H.M. | | 登録日 | 2014-07-29 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase.
Protein Sci., 24, 2015
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8TAR
 | | APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD | | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | | 著者 | Bodrug, T, Welsh, K.A, Bolhuis, D.L, Paulakonis, E, Martinez-Chacin, R.C, Liu, B, Pinkin, N, Bonacci, T, Cui, L, Xu, P, Roscow, O, Amann, S.J, Grishkovskaya, I, Emanuele, M.J, Harrison, J.S, Steimel, J.P, Hahn, K.M, Zhang, W, Zhong, E, Haselbach, D, Brown, N.G. | | 登録日 | 2023-06-27 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
Nat.Struct.Mol.Biol., 30, 2023
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8TAU
 | | APC/C-CDH1-UBE2C-UBE2S-Ubiquitin-CyclinB | | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | | 著者 | Bodrug, T, Welsh, K.A, Bolhuis, D.L, Paulakonis, E, Martinez-Chacin, R.C, Liu, B, Pinkin, N, Bonacci, T, Cui, L, Xu, P, Roscow, O, Amann, S.J, Grishkovskaya, I, Emanuele, M.J, Harrison, J.S, Steimel, J.P, Hahn, K.M, Zhang, W, Zhong, E, Haselbach, D, Brown, N.G. | | 登録日 | 2023-06-27 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
Nat.Struct.Mol.Biol., 30, 2023
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