3SHB
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![BU of 3shb by Molmil](/molmil-images/mine/3shb) | Crystal Structure of PHD Domain of UHRF1 | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Histone H3 peptide, ZINC ION | 著者 | Hu, L, Li, Z, Wang, P, Lin, Y, Xu, Y. | 登録日 | 2011-06-16 | 公開日 | 2011-08-24 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of PHD domain of UHRF1 and insights into recognition of unmodified histone H3 arginine residue 2. Cell Res., 2011
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4N7R
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![BU of 4n7r by Molmil](/molmil-images/mine/4n7r) | Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with its binding protein | 分子名称: | Genomic DNA, chromosome 3, P1 clone: MXL8, ... | 著者 | Zhao, A, Fang, Y, Lin, Y, Gong, W, Liu, L. | 登録日 | 2013-10-16 | 公開日 | 2014-05-14 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with its stimulator protein Proc.Natl.Acad.Sci.USA, 111, 2014
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4QQN
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![BU of 4qqn by Molmil](/molmil-images/mine/4qqn) | Protein arginine methyltransferase 3 in complex with compound MTV044246 | 分子名称: | 1-{2-[1-(aminomethyl)cyclohexyl]ethyl}-3-isoquinolin-6-ylurea, CHLORIDE ION, GLYCEROL, ... | 著者 | Dong, A, Dobrovetsky, E, Tempel, W, He, H, Zhao, K, Smil, D, Landon, M, Luo, X, Chen, Z, Dai, M, Yu, Z, Lin, Y, Zhang, H, Zhao, K, Schapira, M, Brown, P.J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Vedadi, M, Structural Genomics Consortium (SGC) | 登録日 | 2014-06-27 | 公開日 | 2014-09-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3). J. Med. Chem., 61, 2018
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2OEY
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![BU of 2oey by Molmil](/molmil-images/mine/2oey) | Solution Structure of a Designed Spirocyclic Helical Ligand Binding at a Two-Base Bulge Site in DNA | 分子名称: | (1R,3A'S,10'S,10A'R)-7-METHOXY-2-OXO-10',10A'-DIHYDRO-2H,3A'H-SPIRO[NAPHTHALENE-1,3'-PENTALENO[1,2-B]NAPHTHALEN]-10'-YL 2,6-DIDEOXY-2-(METHYLAMINO)-ALPHA-D-GALACTOPYRANOSIDE, DNA (25-MER) | 著者 | Zhang, N, Lin, Y, Xiao, Z, Jones, G.B, Goldberg, I.H. | 登録日 | 2007-01-01 | 公開日 | 2007-04-10 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of a Designed Spirocyclic Helical Ligand Binding at a Two-Base Bulge Site in DNA. Biochemistry, 46, 2007
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4MDR
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![BU of 4mdr by Molmil](/molmil-images/mine/4mdr) | Crystal structure of adaptor protein complex 4 (AP-4) mu4 subunit C-terminal domain D190A mutant, in complex with a sorting peptide from the amyloid precursor protein (APP) | 分子名称: | AP-4 complex subunit mu-1, Amyloid beta A4 protein | 著者 | Ross, B.H, Lin, Y, Corales, E.A, Burgos, P.V, Mardones, G.A. | 登録日 | 2013-08-23 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural and Functional Characterization of Cargo-Binding Sites on the mu 4-Subunit of Adaptor Protein Complex 4. Plos One, 9, 2014
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5U6I
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![BU of 5u6i by Molmil](/molmil-images/mine/5u6i) | Discovery of MLi-2, an Orally Available and Selective LRRK2 Inhibitor that Reduces Brain Kinase Activity | 分子名称: | 3-[2-(morpholin-4-yl)pyridin-4-yl]-5-[(propan-2-yl)oxy]-1H-indazole, Mitogen-activated protein kinase 1, SULFATE ION | 著者 | Scott, J.D, DeMong, D.E, Fell, M.J, Mirescu, C, Basu, K, Greshock, T.J, Morrow, J.A, Xiao, L, Hruza, A, Harris, J, Tiscia, H.E, Chang, R.K, Embrey, M.W, McCauley, J.A, Li, W, Lin, S, Liu, H, Dai, X, Baptista, M, Agnihotri, G, Columbus, J, Mei, H, Poirier, M, Zhou, X, Lin, Y, Yin, Z, Sanders, J.M, Drolet, R.E, Kern, J.T, Kennedy, M.E, Parker, E.M, Stamford, A.W, Nargund, R, Miller, M.W. | 登録日 | 2016-12-08 | 公開日 | 2017-03-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity. J. Med. Chem., 60, 2017
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2N3Z
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![BU of 2n3z by Molmil](/molmil-images/mine/2n3z) | Solution NMR Structure of de novo designed protein, Rossmann2x2 Fold, Northeast Structural Genomics Consortium (NESG) Target OR446 | 分子名称: | OR446 | 著者 | Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Pederson, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2015-06-15 | 公開日 | 2015-09-16 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of DE NOVO DESIGNED PROTEIN, Rossmann2x2 Fold, Northeast Structural Genomics Consortium (NESG) Target OR446 To be Published
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2N2T
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![BU of 2n2t by Molmil](/molmil-images/mine/2n2t) | Solution NMR Structure of DE NOVO DESIGNED PROTEIN (FDA_60), Northeast Structural Genomics Consortium (NESG) Target OR303 | 分子名称: | OR303 | 著者 | Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Hamilton, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2015-05-14 | 公開日 | 2015-09-16 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of DE NOVO DESIGNED PROTEIN (FDA_60), Northeast Structural Genomics Consortium (NESG) Target OR303 To be Published
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2N2U
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![BU of 2n2u by Molmil](/molmil-images/mine/2n2u) | Solution NMR Structure of DE NOVO DESIGNED Ferredoxin Fold PROTEIN sfr3, Northeast Structural Genomics Consortium (NESG) Target OR358 | 分子名称: | OR358 | 著者 | Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Hamilton, K, Pederson, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2015-05-14 | 公開日 | 2015-09-16 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of DE NOVO DESIGNED Ferredoxin Fold PROTEIN sfr3, Northeast Structural Genomics Consortium (NESG) Target OR358 To be Published
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2N76
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![BU of 2n76 by Molmil](/molmil-images/mine/2n76) | Solution NMR Structure of De novo designed protein LFR1 1 with ferredoxin fold, Northeast Structural Genomics Consortium (NESG) Target OR414 | 分子名称: | De novo designed protein LFR1 | 著者 | Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Pederson, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2015-09-03 | 公開日 | 2016-01-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of De novo designed protein LFR1 1 with ferredoxin fold, Northeast Structural Genomics Consortium (NESG) Target OR414 To be Published
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8IMZ
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![BU of 8imz by Molmil](/molmil-images/mine/8imz) | Cryo-EM structure of mouse Piezo1-MDFIC complex (composite map) | 分子名称: | MyoD family inhibitor domain-containing protein, Piezo-type mechanosensitive ion channel component 1 | 著者 | Zhou, Z, Ma, X, Lin, Y, Cheng, D, Bavi, N, Li, J.V, Sutton, D, Yao, M, Harvey, N, Corry, B, Zhang, Y, Cox, C.D. | 登録日 | 2023-03-07 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels. Science, 381, 2023
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2N75
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![BU of 2n75 by Molmil](/molmil-images/mine/2n75) | Solution NMR Structure of De novo designed protein, Rossmann2x2 Fold, Northeast Structural Genomics Consortium (NESG) Target OR446 | 分子名称: | De novo designed protein | 著者 | Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Pederson, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2015-09-03 | 公開日 | 2016-01-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of De novo designed protein, Rossmann2x2 Fold, Northeast Structural Genomics Consortium (NESG) Target OR446 To be Published
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2MQ8
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![BU of 2mq8 by Molmil](/molmil-images/mine/2mq8) | Solution NMR Structure of De novo designed protein LFR1 1 with ferredoxin fold, Northeast Structural Genomics Consortium (NESG) Target OR414 | 分子名称: | De novo designed protein LFR1 | 著者 | Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Pederson, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2014-06-12 | 公開日 | 2014-08-20 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Control over overall shape and size in de novo designed proteins. Proc.Natl.Acad.Sci.USA, 112, 2015
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1DUJ
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![BU of 1duj by Molmil](/molmil-images/mine/1duj) | SOLUTION STRUCTURE OF THE SPINDLE ASSEMBLY CHECKPOINT PROTEIN HUMAN MAD2 | 分子名称: | SPINDLE ASSEMBLY CHECKPOINT PROTEIN | 著者 | Luo, X, Fang, G, Coldiron, M, Lin, Y, Yu, H. | 登録日 | 2000-01-17 | 公開日 | 2000-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. Nat.Struct.Biol., 7, 2000
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2LKN
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![BU of 2lkn by Molmil](/molmil-images/mine/2lkn) | Solution structure of the PPIase domain of human aryl-hydrocarbon receptor-interacting protein (AIP) | 分子名称: | AH receptor-interacting protein | 著者 | Linnert, M, Lin, Y, Manns, A, Haupt, K, Paschke, A, Fischer, G, Weiwad, M, Luecke, C. | 登録日 | 2011-10-17 | 公開日 | 2012-10-17 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The FKBP-Type Domain of the Human Aryl Hydrocarbon Receptor-Interacting Protein Reveals an Unusual Hsp90 Interaction. Biochemistry, 52, 2013
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1I7K
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![BU of 1i7k by Molmil](/molmil-images/mine/1i7k) | |
2HGA
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![BU of 2hga by Molmil](/molmil-images/mine/2hga) | Solution NMR Structure of Conserved protein MTH1368, Northeast Structural Genomics Consortium Target TT821A | 分子名称: | Conserved protein MTH1368 | 著者 | Liu, G, Lin, Y, Parish, D, Shen, Y, Sukumaran, D, Yee, A, Semesi, A, Arrowsmith, C, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-06-26 | 公開日 | 2006-07-25 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of Conserved protein MTH1368, Northeast Structural Genomics Consortium Target TT821A TO BE PUBLISHED
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2GHV
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![BU of 2ghv by Molmil](/molmil-images/mine/2ghv) | Crystal structure of SARS spike protein receptor binding domain | 分子名称: | Spike glycoprotein | 著者 | Hwang, W.C, Lin, Y, Santelli, E, Sui, J, Jaroszewski, L, Stec, B, Farzan, M, Marasco, W.A, Liddington, R.C. | 登録日 | 2006-03-27 | 公開日 | 2006-09-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R. J.Biol.Chem., 281, 2006
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4V0J
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![BU of 4v0j by Molmil](/molmil-images/mine/4v0j) | The channel-block Ser202Glu, Thr104Lys double mutant of Stearoyl-ACP- Desaturase from Castor bean (Ricinus communis) | 分子名称: | ACYL-[ACYL-CARRIER-PROTEIN] DESATURASE, CHLOROPLASTIC, FE (II) ION, ... | 著者 | Moche, M, Guy, J, Whittle, E, Lindqvist, Y, Shanklin, J. | 登録日 | 2014-09-17 | 公開日 | 2015-08-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Half-of-the-Sites Reactivity of the Castor Delta9-18:0-Acp Desaturase. Plant Physiol., 169, 2015
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7PP7
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![BU of 7pp7 by Molmil](/molmil-images/mine/7pp7) | Thunberia alata 16:0-ACP desaturase | 分子名称: | Acyl-[acyl-carrier-protein] 6-desaturase, FE (III) ION | 著者 | Guy, J.E, Whittle, E, Cai, Y, Chai, J, Lindqvist, Y, Shanklin, J. | 登録日 | 2021-09-13 | 公開日 | 2021-12-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Regioselectivity mechanism of the Thunbergia alata Delta 6-16:0-acyl carrier protein desaturase. Plant Physiol., 188, 2022
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7XM8
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![BU of 7xm8 by Molmil](/molmil-images/mine/7xm8) | |
6SL5
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![BU of 6sl5 by Molmil](/molmil-images/mine/6sl5) | Dunaliella Photosystem I Supercomplex | 分子名称: | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ... | 著者 | Nelson, N, Caspy, I, Malavath, T, Klaiman, D, Shkolinsky, Y. | 登録日 | 2019-08-18 | 公開日 | 2020-06-24 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Structure and energy transfer pathways of the Dunaliella Salina photosystem I supercomplex. Biochim Biophys Acta Bioenerg, 1861, 2020
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6STD
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![BU of 6std by Molmil](/molmil-images/mine/6std) | SCYTALONE DEHYDRATASE PLUS INHIBITOR 3 | 分子名称: | 2,2-DICHLORO-1-METHANESULFINYL-3-METHYL-CYCLOPROPANECARBOXYLIC ACID [1-(4-BROMO-PHENYL)-ETHYL]-AMIDE, CALCIUM ION, Scytalone dehydratase | 著者 | Wawrzak, Z, Sandalova, T, Steffens, J.J, Basarab, G.S, Lundqvist, T, Lindqvist, Y, Jordan, D.B. | 登録日 | 1999-02-11 | 公開日 | 1999-12-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | High-resolution structures of scytalone dehydratase-inhibitor complexes crystallized at physiological pH. Proteins, 35, 1999
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6YXR
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![BU of 6yxr by Molmil](/molmil-images/mine/6yxr) | Dunaliella Minimal Photosystem I | 分子名称: | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ... | 著者 | Nelson, N, Caspy, I, Malavath, T, Klaiman, D, Shkolinsky, Y. | 登録日 | 2020-05-03 | 公開日 | 2020-07-01 | 最終更新日 | 2020-07-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure and energy transfer pathways of the Dunaliella Salina photosystem I supercomplex. Biochim Biophys Acta Bioenerg, 1861, 2020
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2K02
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![BU of 2k02 by Molmil](/molmil-images/mine/2k02) | |