6KZ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kz1 by Molmil](/molmil-images/mine/6kz1) | Complex structure of Whirlin and Myosin XVa | Descriptor: | Myosin XVa, Whirlin | Authors: | Lin, L, Wang, M, Shi, Y, Zhu, J, Zhang, R. | Deposit date: | 2019-09-22 | Release date: | 2020-09-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.694 Å) | Cite: | Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex. Cell Rep, 34, 2021
|
|
6XKK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xkk by Molmil](/molmil-images/mine/6xkk) | Cryo-EM structure of the NLRP1-CARD filament | Descriptor: | NACHT, LRR and PYD domains-containing protein 1 | Authors: | Hollingsworth, L.R, David, L, Li, Y, Sharif, H, Fontana, P, Fu, T, Wu, H. | Deposit date: | 2020-06-26 | Release date: | 2020-11-25 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. Nat Commun, 12, 2021
|
|
6XKJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xkj by Molmil](/molmil-images/mine/6xkj) | Cryo-EM structure of CARD8-CARD filament | Descriptor: | Caspase recruitment domain-containing protein 8 | Authors: | Hollingsworth, L.R, David, L, Li, Y, Sharif, H, Fontana, P, Fu, T, Wu, H. | Deposit date: | 2020-06-26 | Release date: | 2020-11-25 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. Nat Commun, 12, 2021
|
|
4UA2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ua2 by Molmil](/molmil-images/mine/4ua2) | Crystal structure of dual function transcriptional regulator MerR from Bacillus megaterium MB1 | Descriptor: | Regulatory protein | Authors: | Lin, L.Y, Chang, C.C, Zou, X.W, Huang, C.C, Chan, N.L. | Deposit date: | 2014-08-07 | Release date: | 2015-07-22 | Last modified: | 2020-01-29 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural basis of the mercury(II)-mediated conformational switching of the dual-function transcriptional regulator MerR Nucleic Acids Res., 43, 2015
|
|
7BYJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7byj by Molmil](/molmil-images/mine/7byj) | Crystal structure of the FERM domain of FRMPD4 | Descriptor: | FERM and PDZ domain-containing protein 4 | Authors: | Lin, L, Wang, M, Wang, C, Zhu, J. | Deposit date: | 2020-04-23 | Release date: | 2020-12-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structure of the FERM domain of a neural scaffold protein FRMPD4 implicated in X-linked intellectual disability. Biochem.J., 477, 2020
|
|
5YMR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ymr by Molmil](/molmil-images/mine/5ymr) | The Crystal Structure of IseG | Descriptor: | 2-hydroxyethylsulfonic acid, Formate acetyltransferase, GLYCEROL | Authors: | Lin, L, Zhang, J, Xing, M, Hua, G, Guo, C, Hu, Y, Wei, Y, Ang, E, Zhao, H, Zhang, Y, Yuchi, Z. | Deposit date: | 2017-10-22 | Release date: | 2019-03-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria. Nat Commun, 10, 2019
|
|
5Y9V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y9v by Molmil](/molmil-images/mine/5y9v) | Crystal structure of diamondback moth ryanodine receptor N-terminal domain | Descriptor: | CHLORIDE ION, GLYCEROL, Ryanodine receptor 1 | Authors: | Lin, L, Yuchi, Z. | Deposit date: | 2017-08-28 | Release date: | 2017-12-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.841 Å) | Cite: | Crystal structure of ryanodine receptor N-terminal domain from Plutella xylostella reveals two potential species-specific insecticide-targeting sites. Insect Biochem. Mol. Biol., 92, 2017
|
|
5TCK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5tck by Molmil](/molmil-images/mine/5tck) | Second Bromodomain from Leishmania donovani LdBPK.091320 complexed with Bromosporine | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Bromosporine, ... | Authors: | Lin, L.-H, Hou, C.F.D, Loppnau, P, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Hui, R, Walker, J.R, Structural Genomics Consortium (SGC) | Deposit date: | 2016-09-15 | Release date: | 2016-11-09 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Second Bromodomain from Leishmania donovani LdBPK.091320 complexed with Bromosporine To Be Published
|
|
6JKK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jkk by Molmil](/molmil-images/mine/6jkk) | Crystal structure of BubR1 kinase domain | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Mitotic checkpoint control protein kinase BUB1 | Authors: | Lin, L, Ye, S, Huang, Y, Liu, X, Zhang, R, Yao, X. | Deposit date: | 2019-03-01 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res., 29, 2019
|
|
6JKM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jkm by Molmil](/molmil-images/mine/6jkm) | Crystal structure of BubR1 kinase domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Lin, L, Ye, S, Huang, Y, Liu, X, Zhang, R, Yao, X. | Deposit date: | 2019-03-01 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res., 29, 2019
|
|
2YK4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2yk4 by Molmil](/molmil-images/mine/2yk4) | Structure of Neisseria LOS-specific sialyltransferase (NST). | Descriptor: | 1,2-ETHANEDIOL, 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOX Y}-ETHOXY)-ETHANOL, CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE, ... | Authors: | Lin, L.Y.C, Rakic, B, Chiu, C.P.C, Lameignere, E, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J. | Deposit date: | 2011-05-25 | Release date: | 2011-08-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria Meningitidis J.Biol.Chem., 286, 2011
|
|
2YK5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2yk5 by Molmil](/molmil-images/mine/2yk5) | Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CMP. | Descriptor: | 1,2-ETHANEDIOL, CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE, CYTIDINE-5'-MONOPHOSPHATE, ... | Authors: | Lin, L.Y.C, Rakic, B, Chiu, C.P.C, Lameignere, E, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J. | Deposit date: | 2011-05-25 | Release date: | 2011-08-31 | Last modified: | 2019-09-25 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria Meningitidis J.Biol.Chem., 286, 2011
|
|
4US3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4us3 by Molmil](/molmil-images/mine/4us3) | Crystal Structure of the bacterial NSS member MhsT in an Occluded Inward-Facing State | Descriptor: | DODECYL-ALPHA-D-MALTOSIDE, SODIUM ION, TRANSPORTER, ... | Authors: | Malinauskaite, L, Quick, M, Reinhard, L, Lyons, J.A, Yano, H, Javitch, J.A, Nissen, P. | Deposit date: | 2014-07-02 | Release date: | 2014-09-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.098 Å) | Cite: | A Mechanism for Intracellular Release of Na+ by Neurotransmitter/Sodium Symporters Nat.Struct.Mol.Biol., 21, 2014
|
|
4US4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4us4 by Molmil](/molmil-images/mine/4us4) | Crystal Structure of the Bacterial NSS Member MhsT in an Occluded Inward-Facing State (lipidic cubic phase form) | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, SODIUM ION, ... | Authors: | Malinauskaite, L, Quick, M, Reinhard, L, Lyons, J.A, Yano, H, Javitch, J.A, Nissen, P. | Deposit date: | 2014-07-02 | Release date: | 2014-09-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A Mechanism for Intracellular Release of Na+ by Neurotransmitter/Sodium Symporters Nat.Struct.Mol.Biol., 21, 2014
|
|
2YK6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2yk6 by Molmil](/molmil-images/mine/2yk6) | Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CDP. | Descriptor: | CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE, CYTIDINE-5'-DIPHOSPHATE, PENTAETHYLENE GLYCOL, ... | Authors: | Lin, L.Y.C, Rakic, B, Chiu, C.P.C, Lameignere, E, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J. | Deposit date: | 2011-05-25 | Release date: | 2011-08-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria Meningitidis J.Biol.Chem., 286, 2011
|
|
6IF2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6if2 by Molmil](/molmil-images/mine/6if2) | Complex structure of Rab35 and its effector RUSC2 | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Iporin, MAGNESIUM ION, ... | Authors: | Lin, L, Zhu, J, Zhang, R. | Deposit date: | 2018-09-18 | Release date: | 2019-04-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase. Structure, 27, 2019
|
|
6IF3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6if3 by Molmil](/molmil-images/mine/6if3) | Complex structure of Rab35 and its effector ACAP2 | Descriptor: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Lin, L, Zhu, J, Zhang, R. | Deposit date: | 2018-09-18 | Release date: | 2019-04-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase. Structure, 27, 2019
|
|
6M9Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m9z by Molmil](/molmil-images/mine/6m9z) | |
2DT4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dt4 by Molmil](/molmil-images/mine/2dt4) | Crystal structure of Pyrococcus horikoshii a plant- and prokaryote-conserved (PPC) protein at 1.60 resolution | Descriptor: | GLYCEROL, Hypothetical protein PH0802 | Authors: | Lin, L, Nakano, H, Uchiyama, S, Fujimoto, S, Matsunaga, S, Nakamura, S. | Deposit date: | 2006-07-10 | Release date: | 2007-05-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of Pyrococcus horikoshii PPC protein at 1.60 A resolution Proteins, 67, 2007
|
|
7EP7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ep7 by Molmil](/molmil-images/mine/7ep7) | The complex structure of Gpsm2 and Whirlin | Descriptor: | G-protein-signaling modulator 2, Whirlin | Authors: | Lin, L, Shi, Y, Wang, C, Zhu, J. | Deposit date: | 2021-04-26 | Release date: | 2022-05-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Promotion of row 1-specific tip complex condensates by Gpsm2-G alpha i provides insights into row identity of the tallest stereocilia. Sci Adv, 8, 2022
|
|
2GSC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gsc by Molmil](/molmil-images/mine/2gsc) | Crystal Structure of the Conserved Hypothetical Cytosolic Protein Xcc0516 from Xanthomonas campestris | Descriptor: | Putative uncharacterized protein XCC0516 | Authors: | Lin, L.Y, Ching, C.L, Chin, K.H, Chou, S.H, Chan, N.L. | Deposit date: | 2006-04-26 | Release date: | 2006-10-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of the conserved hypothetical cytosolic protein Xcc0516 from Xanthomonas campestris reveals a novel quaternary structure assembled by five four-helix bundles. Proteins, 65, 2006
|
|
2YK7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2yk7 by Molmil](/molmil-images/mine/2yk7) | Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CMP-3F-Neu5Ac. | Descriptor: | 1,2-ETHANEDIOL, CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE, CYTIDINE-5'-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC ACID, ... | Authors: | Lin, L.Y.C, Rakic, B, Chiu, C.P.C, Lameignere, E, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J. | Deposit date: | 2011-05-25 | Release date: | 2011-08-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria Meningitidis J.Biol.Chem., 286, 2011
|
|
6X6C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6x6c by Molmil](/molmil-images/mine/6x6c) | Cryo-EM structure of NLRP1-DPP9-VbP complex | Descriptor: | Dipeptidyl peptidase 9, NACHT, LRR and PYD domains-containing protein 1, ... | Authors: | Hollingsworth, L.R, Sharif, H, Griswold, A.R, Fontana, P, Mintseris, J, Dagbay, K.B, Paulo, J.A, Gygi, S.P, Bachovchin, D.A, Wu, H. | Deposit date: | 2020-05-27 | Release date: | 2021-03-10 | Last modified: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation. Nature, 592, 2021
|
|
6X6A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6x6a by Molmil](/molmil-images/mine/6x6a) | Cryo-EM structure of NLRP1-DPP9 complex | Descriptor: | Dipeptidyl peptidase 9, NACHT, LRR and PYD domains-containing protein 1 | Authors: | Hollingsworth, L.R, Sharif, H, Griswold, A.R, Fontana, P, Mintseris, J, Dagbay, K.B, Paulo, J.A, Gygi, S.P, Bachovchin, D.A, Wu, H. | Deposit date: | 2020-05-27 | Release date: | 2021-03-10 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation. Nature, 592, 2021
|
|
6EOK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6eok by Molmil](/molmil-images/mine/6eok) | Crystal structure of E. coli L-asparaginase II | Descriptor: | L-asparaginase 2, ZINC ION | Authors: | Cerofolini, L, Giuntini, S, Carlon, A, Ravera, E, Calderone, V, Fragai, M, Parigi, G, Luchinat, C. | Deposit date: | 2017-10-09 | Release date: | 2018-10-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Characterization of PEGylated Asparaginase: New Opportunities from NMR Analysis of Large PEGylated Therapeutics. Chemistry, 25, 2019
|
|