8QCF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8qcf by Molmil](/molmil-images/mine/8qcf) | yeast cytoplasmic exosome-Ski2 complex degrading a RNA substrate | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Antiviral helicase SKI2, Exosome complex component CSL4, ... | Authors: | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | Deposit date: | 2023-08-25 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.55 Å) | Cite: | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly. Mol.Cell, 83, 2023
|
|
6RFF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rff by Molmil](/molmil-images/mine/6rff) | Human protein kinase CK2 alpha in complex with 2-cyano-2-propenamide compound 7 | Descriptor: | (~{E})-~{N}-(5-bromanyl-1,3,4-thiadiazol-2-yl)-2-cyano-3-(3-nitro-4-oxidanyl-phenyl)prop-2-enamide, 1,2-ETHANEDIOL, Casein kinase II subunit alpha, ... | Authors: | Dalle Vedove, A, Zanforlin, E, Ribaudo, G, Zagotto, G, Battistutta, R, Lolli, G. | Deposit date: | 2019-04-14 | Release date: | 2020-04-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A novel class of selective CK2 inhibitors targeting its open hinge conformation. Eur.J.Med.Chem., 195, 2020
|
|
8SGO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sgo by Molmil](/molmil-images/mine/8sgo) | Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus pregnenolone sulfate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ... | Authors: | Legesse, D.H, Fan, C, Teng, J, Zhuang, Y, Howard, R.J, Noviello, C.M, Lindahl, E, Hibbs, R.E. | Deposit date: | 2023-04-12 | Release date: | 2023-08-30 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | Structural insights into opposing actions of neurosteroids on GABA A receptors. Nat Commun, 14, 2023
|
|
8QO3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8qo3 by Molmil](/molmil-images/mine/8qo3) | Conserved Structures and Dynamics in 5-Proximal Regions of Betacoronavirus RNA Genomes | Descriptor: | RoBat-CoV-SL5 | Authors: | Moura, T.R, Purta, E, Bernat, A, Baulin, E, Mukherjee, S, Bujnicki, J.M. | Deposit date: | 2023-09-28 | Release date: | 2024-03-06 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Conserved structures and dynamics in 5'-proximal regions of Betacoronavirus RNA genomes. Nucleic Acids Res., 52, 2024
|
|
8QO5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8qo5 by Molmil](/molmil-images/mine/8qo5) | Conserved Structures and Dynamics in 5-Proximal Regions of Betacoronavirus RNA Genomes | Descriptor: | SARS-CoV-2-SL5 | Authors: | Moura, T.R, Purta, E, Bernat, A, Baulin, E, Mukherjee, S, Bujnicki, J.M. | Deposit date: | 2023-09-28 | Release date: | 2024-03-06 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Conserved structures and dynamics in 5'-proximal regions of Betacoronavirus RNA genomes. Nucleic Acids Res., 52, 2024
|
|
8QO2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8qo2 by Molmil](/molmil-images/mine/8qo2) | Conserved Structures and Dynamics in 5-Proximal Regions of Betacoronavirus RNA Genomes | Descriptor: | OC43-CoV-SL5 | Authors: | Moura, T.R, Purta, E, Bernat, A, Baulin, E, Mukherjee, S, Bujnicki, J.M. | Deposit date: | 2023-09-27 | Release date: | 2024-03-06 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (7.1 Å) | Cite: | Conserved structures and dynamics in 5'-proximal regions of Betacoronavirus RNA genomes. Nucleic Acids Res., 52, 2024
|
|
6RCM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rcm by Molmil](/molmil-images/mine/6rcm) | Human protein kinase CK2 alpha in complex with 2-cyano-2-propenamide compound 3 | Descriptor: | (~{E})-~{N}-(5-~{tert}-butyl-1,3,4-thiadiazol-2-yl)-2-cyano-3-(3-methoxy-4-oxidanyl-phenyl)prop-2-enamide, 1,2-ETHANEDIOL, Casein kinase II subunit alpha, ... | Authors: | Dalle Vedove, A, Zanforlin, E, Ribaudo, G, Zagotto, G, Battistutta, R, Lolli, G. | Deposit date: | 2019-04-11 | Release date: | 2020-04-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A novel class of selective CK2 inhibitors targeting its open hinge conformation. Eur.J.Med.Chem., 195, 2020
|
|
8F6C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f6c by Molmil](/molmil-images/mine/8f6c) | E. coli cytochrome bo3 ubiquinol oxidase dimer | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | Authors: | Guo, Y, Karimullina, E, Borek, D, Savchenko, A. | Deposit date: | 2022-11-16 | Release date: | 2022-11-30 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Monomer and dimer structures of cytochrome bo 3 ubiquinol oxidase from Escherichia coli. Protein Sci., 32, 2023
|
|
8F68
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f68 by Molmil](/molmil-images/mine/8f68) | E. coli cytochrome bo3 ubiquinol oxidase monomer | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | Authors: | Guo, Y, Karimullina, E, Borek, D, Savchenko, A. | Deposit date: | 2022-11-16 | Release date: | 2022-11-30 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Monomer and dimer structures of cytochrome bo 3 ubiquinol oxidase from Escherichia coli. Protein Sci., 32, 2023
|
|
8QO4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8qo4 by Molmil](/molmil-images/mine/8qo4) | Conserved Structures and Dynamics in 5-Proximal Regions of Betacoronavirus RNA Genomes | Descriptor: | MERS-CoV-SL5 | Authors: | Moura, T.R, Purta, E, Bernat, A, Baulin, E, Mukherjee, S, Bujnicki, J.M. | Deposit date: | 2023-09-28 | Release date: | 2024-03-06 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Conserved structures and dynamics in 5'-proximal regions of Betacoronavirus RNA genomes. Nucleic Acids Res., 52, 2024
|
|
6T8H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6t8h by Molmil](/molmil-images/mine/6t8h) | Cryo-EM structure of the DNA-bound PolD-PCNA processive complex from P. abyssi | Descriptor: | DNA polymerase II small subunit, DNA polymerase sliding clamp, DNA primer, ... | Authors: | Madru, C, Raia, P, Hugonneau Beaufet, I, Pehau-Arnaudet, G, England, P, Lindhal, E, Delarue, M, Carroni, M, Sauguet, L. | Deposit date: | 2019-10-24 | Release date: | 2020-03-04 | Last modified: | 2020-04-08 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA. Nat Commun, 11, 2020
|
|
8K65
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k65 by Molmil](/molmil-images/mine/8k65) | Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase without pump laser irradiation | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CARBON MONOXIDE, COPPER (II) ION, ... | Authors: | Safari, C, Ghosh, S, Andersson, R, Johannesson, J, Donoso, A.V, Bath, P, Zoric, D, Sandelin, E, Nango, E, Tanaka, R, Iwata, S, Neutze, R, Branden, G. | Deposit date: | 2023-07-25 | Release date: | 2023-11-15 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Time-resolved serial crystallography to track the dynamics of carbon monoxide in the active site of cytochrome c oxidase. Sci Adv, 9, 2023
|
|
8F3C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f3c by Molmil](/molmil-images/mine/8f3c) | Cryo-EM consensus structure of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase minus preQ1 ligand | Descriptor: | DNA (38-MER), DNA (39-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Porta, J.C, Chauvier, A, Deb, I, Ellinger, E, Frank, A.T, Meze, K, Ohi, M.D, Walter, N.G. | Deposit date: | 2022-11-09 | Release date: | 2023-06-21 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand. Nat.Struct.Mol.Biol., 30, 2023
|
|
8P7C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p7c by Molmil](/molmil-images/mine/8p7c) | |
8AW3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8aw3 by Molmil](/molmil-images/mine/8aw3) | Cryo-EM structure of the Tb ADAT2/3 deaminase in complex with tRNA | Descriptor: | Deaminase, putative, RNA (75-MER), ... | Authors: | Dolce, L.G, Tengo, L, Weis, F, Kowalinski, E. | Deposit date: | 2022-08-29 | Release date: | 2022-11-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for sequence-independent substrate selection by eukaryotic wobble base tRNA deaminase ADAT2/3. Nat Commun, 13, 2022
|
|
8ATG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8atg by Molmil](/molmil-images/mine/8atg) | Pentameric ligand-gated ion channel GLIC with bound lipids | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Proton-gated ion channel | Authors: | Bergh, C, Rovsnik, U, Howard, R.J, Lindahl, E. | Deposit date: | 2022-08-23 | Release date: | 2023-09-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM. Elife, 12, 2024
|
|
8K6Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k6y by Molmil](/molmil-images/mine/8k6y) | Serial femtosecond crystallography structure of photo dissociated CO from ba3- type cytochrome c oxidase determined by extrapolation method | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CARBON MONOXIDE, COPPER (II) ION, ... | Authors: | Safari, C, Ghosh, S, Andersson, R, Johannesson, J, Donoso, A.V, Zoric, D, Sandelin, E, Iwata, S, Neutze, R, Branden, G. | Deposit date: | 2023-07-25 | Release date: | 2023-11-15 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Time-resolved serial crystallography to track the dynamics of carbon monoxide in the active site of cytochrome c oxidase. Sci Adv, 9, 2023
|
|
4YCB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ycb by Molmil](/molmil-images/mine/4ycb) | Structure of a single tryptophan mutant of Acetobacter aceti PurE | Descriptor: | 1,2-ETHANEDIOL, 2,5,8,11-TETRAOXATRIDECANE, ACETATE ION, ... | Authors: | Kappock, T.J, Sullivan, K.L, Mullins, E.A. | Deposit date: | 2015-02-19 | Release date: | 2016-02-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure of a single tryptophan mutant of Acetobacter aceti PurE To Be Published
|
|
7XD7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xd7 by Molmil](/molmil-images/mine/7xd7) | The pre-Tet-C state of wild-type Tetrahymena group I intron with 30nt 3'/5'-exon | Descriptor: | MAGNESIUM ION, SPERMIDINE, The pre-Tet-C state molecule of co-transcriptional folded wild-type Tetrahymena group I intron with 30nt 3'/5'-exon | Authors: | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | Deposit date: | 2022-03-26 | Release date: | 2023-03-29 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing Nat Catal, 2023
|
|
7XD3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xd3 by Molmil](/molmil-images/mine/7xd3) | The relaxed pre-Tet-S1 state of wild-type Tetrahymena group I intron with 6nt 3'/5'-exon | Descriptor: | MAGNESIUM ION, The relaxed pre-Tet-S1 state molecule of co-transcriptional folded wild-type Tetrahymena group I intron with 6nt 3'/5'-exon | Authors: | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | Deposit date: | 2022-03-26 | Release date: | 2023-03-29 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4.05 Å) | Cite: | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing Nat Catal, 2023
|
|
7XD5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xd5 by Molmil](/molmil-images/mine/7xd5) | The Tet-S2 state of wild-type Tetrahymena group I intron with 30nt 3'/5'-exon | Descriptor: | MAGNESIUM ION, SPERMIDINE, The Tet-S2 state molecule of co-transcriptional folded wild-type Tetrahymena group I intron with 30nt 3'/5'-exon (5'-exon), ... | Authors: | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | Deposit date: | 2022-03-26 | Release date: | 2023-04-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing Nat Catal, 2023
|
|
7XD4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xd4 by Molmil](/molmil-images/mine/7xd4) | The intermediate pre-Tet-S1 state of wild-type Tetrahymena group I intron with 6nt 3'/5'-exon | Descriptor: | Co-transcriptional folded wild-type Tetrahymena group I intron with 6nt 3'/5'-exon, MAGNESIUM ION | Authors: | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | Deposit date: | 2022-03-26 | Release date: | 2023-03-29 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.89 Å) | Cite: | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing Nat Catal, 2023
|
|
7XD6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xd6 by Molmil](/molmil-images/mine/7xd6) | The Tet-S2 state with a pseudoknotted 4-way junction of wild-type Tetrahymena group I intron with 30nt 3'/5'-exon | Descriptor: | MAGNESIUM ION, SPERMIDINE, The Tet-S2 state with a pseudoknotted 4-way junction molecule of co-transcriptional folded wild-type Tetrahymena group I intron with 30nt 3'/5'-exon (5'-exon), ... | Authors: | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | Deposit date: | 2022-03-26 | Release date: | 2023-04-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing Nat Catal, 2023
|
|
5DGC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dgc by Molmil](/molmil-images/mine/5dgc) | Reaction of phosphorylated CheY with imidazole 2 of 3 | Descriptor: | BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, Chemotaxis protein CheY, ... | Authors: | Page, S, Silversmith, R.E, Bourret, R.B, Collins, E.J. | Deposit date: | 2015-08-27 | Release date: | 2016-03-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Imidazole as a Small Molecule Analogue in Two-Component Signal Transduction. Biochemistry, 54, 2015
|
|
8BTK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8btk by Molmil](/molmil-images/mine/8btk) | Structure of the TRAP complex with the Sec translocon and a translating ribosome | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | Authors: | Jaskolowski, M, Jomaa, A, Gamerdinger, M, Shrestha, S, Leibundgut, M, Deuerling, E, Ban, N. | Deposit date: | 2022-11-29 | Release date: | 2023-05-24 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular basis of the TRAP complex function in ER protein biogenesis. Nat.Struct.Mol.Biol., 30, 2023
|
|