8AW3

Cryo-EM structure of the Tb ADAT2/3 deaminase in complex with tRNA

Summary for 8AW3

Entry DOI	10.2210/pdb8aw3/pdb
EMDB information	15690
Descriptor	RNA (75-MER), Deaminase, putative, ZINC ION, ... (4 entities in total)
Functional Keywords	adat; inosine; trna modification; deaminase; cryo-em structure; trypanosoma brucei, rna binding protein
Biological source	Trypanosoma brucei brucei More
Total number of polymer chains	3
Total formula weight	88410.92
Authors	Dolce, L.G.,Tengo, L.,Weis, F.,Kowalinski, E. (deposition date: 2022-08-29, release date: 2022-11-16, Last modification date: 2024-03-27)
Primary citation	Dolce, L.G.,Zimmer, A.A.,Tengo, L.,Weis, F.,Rubio, M.A.T.,Alfonzo, J.D.,Kowalinski, E. Structural basis for sequence-independent substrate selection by eukaryotic wobble base tRNA deaminase ADAT2/3. Nat Commun, 13:6737-6737, 2022 Cited by PubMed: 36347890 DOI: 10.1038/s41467-022-34441-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation