8FF0
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8GMB
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![BU of 8gmb by Molmil](/molmil-images/mine/8gmb) | Crystal structure of the full-length Bruton's tyrosine kinase (PH-TH domain not visible) | 分子名称: | 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, Tyrosine-protein kinase BTK | 著者 | Lin, D.Y, Andreotti, A.H. | 登録日 | 2023-03-24 | 公開日 | 2023-08-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Elife, 12, 2024
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8FD9
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3NAW
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3NB2
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![BU of 3nb2 by Molmil](/molmil-images/mine/3nb2) | Crystal structure of E. coli O157:H7 effector protein NleL | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... | 著者 | Lin, D.Y, Chen, J. | 登録日 | 2010-06-02 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7. J.Biol.Chem., 286, 2011
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3BIK
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![BU of 3bik by Molmil](/molmil-images/mine/3bik) | Crystal Structure of the PD-1/PD-L1 Complex | 分子名称: | GLYCEROL, Programmed cell death 1 ligand 1, Programmed cell death protein 1 | 著者 | Lin, D.Y, Tanaka, Y, Iwasaki, M, Gittis, A.G, Su, H.P, Mikami, B, Okazaki, T, Honjo, T, Minato, N, Garboczi, D.N. | 登録日 | 2007-11-30 | 公開日 | 2008-02-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BIS
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![BU of 3bis by Molmil](/molmil-images/mine/3bis) | Crystal Structure of the PD-L1 | 分子名称: | Programmed cell death 1 ligand 1 | 著者 | Lin, D.Y, Tanaka, Y, Iwasaki, M, Gittis, A.G, Su, H.P, Mikami, B, Okazaki, T, Honjo, T, Minato, N, Garboczi, D.N. | 登録日 | 2007-11-30 | 公開日 | 2008-02-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3SQV
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![BU of 3sqv by Molmil](/molmil-images/mine/3sqv) | Crystal Structure of E. coli O157:H7 E3 ubiquitin ligase, NleL, with a human E2, UbcH7 | 分子名称: | GLYCEROL, SULFATE ION, Ubiquitin-conjugating enzyme E2 L3, ... | 著者 | Lin, D.Y, Chen, J. | 登録日 | 2011-07-06 | 公開日 | 2012-01-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions. Proc.Natl.Acad.Sci.USA, 109, 2012
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8S9F
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8S93
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![BU of 8s93 by Molmil](/molmil-images/mine/8s93) | Crystal structure of the PH-TH/kinase complex of Bruton's tyrosine kinase | 分子名称: | 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, GLYCEROL, Tyrosine-protein kinase BTK, ... | 著者 | Lin, D.Y, Andreotti, A.H. | 登録日 | 2023-03-27 | 公開日 | 2023-08-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Elife, 12, 2024
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3SY2
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2G2Q
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![BU of 2g2q by Molmil](/molmil-images/mine/2g2q) | The crystal structure of G4, the poxviral disulfide oxidoreductase essential for cytoplasmic disulfide bond formation | 分子名称: | Glutaredoxin-2, SULFATE ION | 著者 | Su, H.P, Lin, D.Y, Garboczi, D.N. | 登録日 | 2006-02-16 | 公開日 | 2006-08-01 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The structure of G4, the poxvirus disulfide oxidoreductase essential for virus maturation and infectivity. J.Virol., 80, 2006
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