8B8K
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![BU of 8b8k by Molmil](/molmil-images/mine/8b8k) | Cryo-EM structure of Ca2+-bound mTMEM16F N562A mutant in Digitonin closed/closed | 分子名称: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Anoctamin-6, CALCIUM ION | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | 登録日 | 2022-10-04 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F. Nat Commun, 13, 2022
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8B8J
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![BU of 8b8j by Molmil](/molmil-images/mine/8b8j) | Cryo-EM structure of Ca2+-bound mTMEM16F F518H mutant in Digitonin | 分子名称: | Anoctamin-6, CALCIUM ION | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico Mosina, V, Paulino, C, Dutzler, R. | 登録日 | 2022-10-04 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F. Nat Commun, 13, 2022
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8BC0
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![BU of 8bc0 by Molmil](/molmil-images/mine/8bc0) | Cryo-EM structure of Ca2+-bound mTMEM16F F518A Q623A mutant in GDN open/closed | 分子名称: | Anoctamin-6, CALCIUM ION | 著者 | Arndt, M, Alvadia, C, Straub, M, Clerico-Mosina, V, Paulino, C, Dutzler, R. | 登録日 | 2022-10-14 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F. Nat Commun, 13, 2022
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8BC1
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![BU of 8bc1 by Molmil](/molmil-images/mine/8bc1) | Cryo-EM Structure of Ca2+-bound mTMEM16F F518A_Q623A mutant in GDN | 分子名称: | Anoctamin-6,mTMEM16F, CALCIUM ION | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | 登録日 | 2022-10-14 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F. Nat Commun, 13, 2022
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8B8M
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![BU of 8b8m by Molmil](/molmil-images/mine/8b8m) | Cryo-EM structure of Ca2+-bound mTMEM16F N562A mutant in Digitonin open/closed | 分子名称: | Anoctamin-6, CALCIUM ION | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | 登録日 | 2022-10-04 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F. Nat Commun, 13, 2022
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8Q9N
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![BU of 8q9n by Molmil](/molmil-images/mine/8q9n) | Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and MITR deacetylase binding motif mutant L151V. | 分子名称: | DIMETHYL SULFOXIDE, DNA MADS box, MEF2D protein, ... | 著者 | Chinellato, M, Carli, A, Perin, S, Mazzocato, Y, Biondi, B, Di Giorgio, E, Brancolini, C, Angelini, A, Cendron, L. | 登録日 | 2023-08-20 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA. J.Mol.Biol., 436, 2024
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8B8Q
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![BU of 8b8q by Molmil](/molmil-images/mine/8b8q) | Structure of mTMEM16F in lipid Nanodiscs in the presence of Ca2+ | 分子名称: | Anoctamin-6, CALCIUM ION | 著者 | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | 登録日 | 2022-10-04 | 公開日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Structural basis for the activation of the lipid scramblase TMEM16F. Nat Commun, 13, 2022
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8BMS
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![BU of 8bms by Molmil](/molmil-images/mine/8bms) | Cryo-EM structure of the mutant solitary ECF module 2EQ in MSP2N2 lipid nanodiscs in the ATPase closed and ATP-bound conformation | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, ... | 著者 | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | 登録日 | 2022-11-10 | 公開日 | 2023-08-02 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Expulsion mechanism of the substrate-translocating subunit in ECF transporters. Nat Commun, 14, 2023
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8BMQ
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![BU of 8bmq by Molmil](/molmil-images/mine/8bmq) | Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs bound to AMP-PNP | 分子名称: | Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ... | 著者 | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | 登録日 | 2022-11-10 | 公開日 | 2023-08-02 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Expulsion mechanism of the substrate-translocating subunit in ECF transporters. Nat Commun, 14, 2023
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8BMP
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![BU of 8bmp by Molmil](/molmil-images/mine/8bmp) | Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs bound to ATP and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Energy-coupling factor transporter ATP-binding protein EcfA1, ... | 著者 | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | 登録日 | 2022-11-10 | 公開日 | 2023-08-02 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Expulsion mechanism of the substrate-translocating subunit in ECF transporters. Nat Commun, 14, 2023
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8BMR
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![BU of 8bmr by Molmil](/molmil-images/mine/8bmr) | Cryo-EM structure of the wild-type solitary ECF module in MSP2N2 lipid nanodiscs in the ATPase open and nucleotide-free conformation | 分子名称: | Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT | 著者 | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | 登録日 | 2022-11-10 | 公開日 | 2023-08-02 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Expulsion mechanism of the substrate-translocating subunit in ECF transporters. Nat Commun, 14, 2023
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6G9O
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![BU of 6g9o by Molmil](/molmil-images/mine/6g9o) | Structure of full-length homomeric mLRRC8A volume-regulated anion channel at 4.25 A resolution | 分子名称: | Volume-regulated anion channel subunit LRRC8A | 著者 | Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R. | 登録日 | 2018-04-11 | 公開日 | 2018-05-16 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | 主引用文献 | Structure of a volume-regulated anion channel of the LRRC8 family. Nature, 558, 2018
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7ZRM
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![BU of 7zrm by Molmil](/molmil-images/mine/7zrm) | Cryo-EM map of the unphosphorylated KdpFABC complex in the E1-P_ADP conformation, under turnover conditions | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Dubach, V.R.A, Stansfeld, P.J, Haenelt, I, Paulino, C. | 登録日 | 2022-05-04 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Inhibited KdpFABC transitions into an E1 off-cycle state. Elife, 11, 2022
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6G8Z
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![BU of 6g8z by Molmil](/molmil-images/mine/6g8z) | Structure of the pore domain of homomeric mLRRC8A volume-regulated anion channel at 3.66 A resolution | 分子名称: | Volume-regulated anion channel subunit LRRC8A | 著者 | Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R. | 登録日 | 2018-04-10 | 公開日 | 2018-05-16 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | Structure of a volume-regulated anion channel of the LRRC8 family. Nature, 558, 2018
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7ZRD
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![BU of 7zrd by Molmil](/molmil-images/mine/7zrd) | Cryo-EM map of the WT KdpFABC complex in the E1-P tight conformation, stabilised with the inhibitor orthovanadate | 分子名称: | CARDIOLIPIN, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ... | 著者 | Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Stansfeld, P.J, Haenelt, I, Paulino, C. | 登録日 | 2022-05-04 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Inhibited KdpFABC transitions into an E1 off-cycle state. Elife, 11, 2022
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7ZRE
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![BU of 7zre by Molmil](/molmil-images/mine/7zre) | Cryo-EM map of the WT KdpFABC complex in the E1-P tight conformation, under turnover conditions | 分子名称: | CARDIOLIPIN, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ... | 著者 | Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Dubach, V.R.A, Stansfeld, P.J, Haenelt, I, Paulino, C. | 登録日 | 2022-05-04 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Inhibited KdpFABC transitions into an E1 off-cycle state. Elife, 11, 2022
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7ZRL
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![BU of 7zrl by Molmil](/molmil-images/mine/7zrl) | Cryo-EM map of the unphosphorylated KdpFABC complex in the E2-P conformation, under turnover conditions | 分子名称: | POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, Potassium-transporting ATPase KdpC subunit, ... | 著者 | Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Dubach, V.R.A, Stansfeld, P.J, Haenelt, I, Paulino, C. | 登録日 | 2022-05-04 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Inhibited KdpFABC transitions into an E1 off-cycle state. Elife, 11, 2022
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7ZRK
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![BU of 7zrk by Molmil](/molmil-images/mine/7zrk) | Cryo-EM map of the WT KdpFABC complex in the E1-P_ADP conformation, under turnover conditions | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CARDIOLIPIN, POTASSIUM ION, ... | 著者 | Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Dubach, V.R.A, Stansfeld, P.J, Haenelt, I, Paulino, C. | 登録日 | 2022-05-04 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Inhibited KdpFABC transitions into an E1 off-cycle state. Elife, 11, 2022
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7ZRG
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![BU of 7zrg by Molmil](/molmil-images/mine/7zrg) | Cryo-EM map of the WT KdpFABC complex in the E1_ATPearly conformation, under turnover conditions | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CARDIOLIPIN, POTASSIUM ION, ... | 著者 | Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Rheinberger, J, Wunnicke, D, Dubach, V.R.A, Stansfeld, P.J, Haenelt, I, Paulino, C. | 登録日 | 2022-05-04 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Inhibited KdpFABC transitions into an E1 off-cycle state. Elife, 11, 2022
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7ZRH
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![BU of 7zrh by Molmil](/molmil-images/mine/7zrh) | Cryo-EM structure of the KdpFABC complex in a nucleotide-free E1 conformation loaded with K+ | 分子名称: | CARDIOLIPIN, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ... | 著者 | Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Stansfeld, P.J, Haenelt, I, Paulino, C. | 登録日 | 2022-05-04 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Inhibited KdpFABC transitions into an E1 off-cycle state. Elife, 11, 2022
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7ZRI
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![BU of 7zri by Molmil](/molmil-images/mine/7zri) | Cryo-EM structure of the KdpFABC complex in a nucleotide-free E1 conformation loaded with K+ | 分子名称: | CARDIOLIPIN, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ... | 著者 | Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Stansfeld, P.J, Haenelt, I, Paulino, C. | 登録日 | 2022-05-04 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Inhibited KdpFABC transitions into an E1 off-cycle state. Elife, 11, 2022
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7ZRJ
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![BU of 7zrj by Molmil](/molmil-images/mine/7zrj) | Cryo-EM structure of the KdpFABC complex in a nucleotide-free E1 conformation loaded with K+ | 分子名称: | CARDIOLIPIN, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ... | 著者 | Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Stansfeld, P.J, Haenelt, I, Paulino, C. | 登録日 | 2022-05-04 | 公開日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Inhibited KdpFABC transitions into an E1 off-cycle state. Elife, 11, 2022
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8BTM
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![BU of 8btm by Molmil](/molmil-images/mine/8btm) | Structural and functional studies of geldanamycin amide synthase ShGdmF | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, GdmF | 著者 | Ewert, W, Zeilinger, C, Kirschning, A, Preller, M. | 登録日 | 2022-11-29 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural and functional studies of geldanamycin amide synthase ShGdmF To Be Published
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6RVY
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![BU of 6rvy by Molmil](/molmil-images/mine/6rvy) | |
6RVX
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![BU of 6rvx by Molmil](/molmil-images/mine/6rvx) | |