6RVY

Inward-open structure of the ASCT2 (SLC1A5) mutant C467R in absence of substrate

Summary for 6RVY

• Entry DOI: 10.2210/pdb6rvy/pdb
• Related: 6RVX
• EMDB information: 10016 10017 10018
• Descriptor: Neutral amino acid transporter B(0) (1 entity in total)
• Functional Keywords: solute carrier family 1 (slc1a) one-gate elevator mechanism neutral amino acid exchange membrane proteins cryo-em, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 172565.54

Authors

Garaeva, A.A.,Guskov, A.,Slotboom, D.J.,Paulino, C. (deposition date: 2019-06-03, release date: 2019-08-07, Last modification date: 2019-12-18)

• Primary citation: Garaeva, A.A.,Guskov, A.,Slotboom, D.J.,Paulino, C.; A one-gate elevator mechanism for the human neutral amino acid transporter ASCT2.; Nat Commun, 10:3427-3427, 2019; PubMed: 31366933; DOI: 10.1038/s41467-019-11363-x

Experimental method

ELECTRON MICROSCOPY (4.13 Å)