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PDB: 228 results
9B5C
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BU of 9b5c by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - consensus map and model
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5Q
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BU of 9b5q by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - cluster 2 map and model (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5O
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BU of 9b5o by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from consensus
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5N
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BU of 9b5n by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 1 map and model from consensus
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5U
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BU of 9b5u by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 1 map and model from cluster 1 (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5A
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BU of 9b5a by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 6
Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5L
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BU of 9b5l by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 10 map and model from cluster 5 (Ub(A)-AMP)
Descriptor: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, Polyubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B59
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BU of 9b59 by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 5
Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5X
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BU of 9b5x by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from cluster 5 (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5H
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BU of 9b5h by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 3 map and model (Ub(A)-AMP/PPi/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, Large ribosomal subunit protein eL40B, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
9B5V
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BU of 9b5v by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from cluster 1 (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (3.94 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 633, 2024
5FG1
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BU of 5fg1 by Molmil
Structure of the conserved yeast listerin (Ltn1) selenomethionine-substituted N-terminal domain, TRIGONAL FORM
Descriptor: E3 ubiquitin-protein ligase listerin, POTASSIUM ION
Authors:Doamekpor, S.K, Lima, C.D.
Deposit date:2015-12-19
Release date:2016-07-06
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure and function of the yeast listerin (Ltn1) conserved N-terminal domain in binding to stalled 60S ribosomal subunits.
Proc.Natl.Acad.Sci.USA, 113, 2016
5FG0
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BU of 5fg0 by Molmil
Structure of the conserved yeast listerin (Ltn1) N-terminal domain, MONOCLINIC FORM
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase listerin, POTASSIUM ION
Authors:Doamekpor, S.K, Lima, C.D.
Deposit date:2015-12-19
Release date:2016-07-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structure and function of the yeast listerin (Ltn1) conserved N-terminal domain in binding to stalled 60S ribosomal subunits.
Proc.Natl.Acad.Sci.USA, 113, 2016
4XQ0
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BU of 4xq0 by Molmil
Structure of fission yeast RNA polymerase II CTD phosphatase Fcp1-R271A bound to beryllium fluoride
Descriptor: MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase, TETRAETHYLENE GLYCOL
Authors:Ghosh, A, Lima, C.D.
Deposit date:2015-01-18
Release date:2015-03-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1.
Rna, 21, 2015
4XPZ
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BU of 4xpz by Molmil
Structure of fission yeast RNA polymerase II CTD phosphatase Fcp1-R271A bound to aluminum fluoride
Descriptor: ALUMINUM FLUORIDE, MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase, ...
Authors:Ghosh, A, Lima, C.D.
Deposit date:2015-01-18
Release date:2015-03-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1.
Rna, 21, 2015
8CT4
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BU of 8ct4 by Molmil
Cryo-EM structure of Mtb Lpd bound to inhibitor complex with 2-((2-cyano-N,5-dimethyl-1H-indole)-7-sulfonamido)-N-(4-(oxetan-3-yl)-3,4-dihydro-2H-benzo[b] [1,4]oxazin-7-yl)acetamide
Descriptor: Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, N~2~-(2-cyano-5-methyl-1H-indole-7-sulfonyl)-N~2~-methyl-N-[4-(oxetan-3-yl)-3,4-dihydro-2H-1,4-benzoxazin-7-yl]glycinamide
Authors:Kochanczyk, T, Arango, N, Lima, C.D.
Deposit date:2022-05-13
Release date:2022-05-25
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.17 Å)
Cite:Cryo-EM structure of Mtb Lpd bound to the inhibitor 2-((2-cyano-N,5-dimethyl-1H-indole)-7-sulfonamido)-N-(4-(oxetan-3-yl)-3,4-dihydro-2H-benzo[b] [1,4]oxazin-7-yl)acetamide at 2.17 Angstrom resolution
Not published
6OP8
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BU of 6op8 by Molmil
S. pombe Ubc7/U7BR complex
Descriptor: 1,2-ETHANEDIOL, CUE domain-containing protein 4, mitochondrial, ...
Authors:Hann, Z.S, Lima, C.D.
Deposit date:2019-04-24
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:Crystal structure of the Schizosaccharomyces pombe U7BR E2-binding region in complex with Ubc7.
Acta Crystallogr.,Sect.F, 75, 2019
6D6R
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BU of 6d6r by Molmil
Human nuclear exosome-MTR4 RNA complex - composite map after focused reconstruction
Descriptor: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ...
Authors:Weick, E.-M, Lima, C.D.
Deposit date:2018-04-22
Release date:2018-06-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex.
Cell, 173, 2018
6D6Q
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BU of 6d6q by Molmil
Human nuclear exosome-MTR4 RNA complex - overall reconstruction
Descriptor: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ...
Authors:Weick, E.-M, Lima, C.D.
Deposit date:2018-04-22
Release date:2018-06-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex.
Cell, 173, 2018
6C90
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BU of 6c90 by Molmil
Human Mtr4 helicase in complex with ZCCHC8-CTD
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Exosome RNA helicase MTR4,Exosome RNA helicase MTR4, L(+)-TARTARIC ACID, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2018-01-25
Release date:2018-05-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for MTR4-ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5DEJ
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BU of 5dej by Molmil
Transthyretin natural mutant A19D
Descriptor: CALCIUM ION, Transthyretin
Authors:Pereira, H.M, Ferreira, P, Andrade, C, Lima, C, Palhano, F, Foguel, D.
Deposit date:2015-08-25
Release date:2016-08-31
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Crystal structure of human Transthyretin natural mutant A19D
To Be Published
5D2M
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BU of 5d2m by Molmil
Complex between human SUMO2-RANGAP1, UBC9 and ZNF451
Descriptor: 1,2-ETHANEDIOL, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ...
Authors:Cappadocia, L, Lima, C.D.
Deposit date:2015-08-05
Release date:2015-11-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase.
Nat.Struct.Mol.Biol., 22, 2015
8DAW
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BU of 8daw by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to three ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 2 (uD)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
Authors:Lee, H.G, Lima, C.D.
Deposit date:2022-06-14
Release date:2022-11-30
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DAU
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BU of 8dau by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two folded ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (uA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
Authors:Lee, H.G, Lima, C.D.
Deposit date:2022-06-14
Release date:2022-11-30
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DAR
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BU of 8dar by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex unbound but in the presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
Authors:Lee, H.G, Lima, C.D.
Deposit date:2022-06-14
Release date:2022-11-30
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023

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PDB entries from 2024-10-09

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