6D6Q

Human nuclear exosome-MTR4 RNA complex - overall reconstruction

Summary for 6D6Q

Entry DOI	10.2210/pdb6d6q/pdb
EMDB information	7808 7809 7810 7812 7813 7814 7815 7818 7819
Descriptor	Exosome complex component RRP45, Exosome component 10, Exosome complex exonuclease RRP44, ... (18 entities in total)
Functional Keywords	rna exosome, rna degradation, ribonuclease, helicase, sf2, rna-protein complex, translocase, nuclear, hydrolase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	15
Total formula weight	639178.81
Authors	Weick, E.-M.,Lima, C.D. (deposition date: 2018-04-22, release date: 2018-06-20, Last modification date: 2024-03-13)
Primary citation	Weick, E.M.,Puno, M.R.,Januszyk, K.,Zinder, J.C.,DiMattia, M.A.,Lima, C.D. Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex. Cell, 173:1663-, 2018 Cited by PubMed: 29906447 DOI: 10.1016/j.cell.2018.05.041 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.45 Å)

Structure validation