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PDB: 229 件
5K36
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Structure of an eleven component nuclear RNA exosome complex bound to RNA
分子名称: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ...
著者Lima, C.D, Zinder, J.C.
登録日2016-05-19
公開日2016-11-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Nuclear RNA Exosome at 3.1 angstrom Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3.
Mol.Cell, 64, 2016
1JF9
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BU of 1jf9 by Molmil
Crystal Structure of selenocysteine lyase
分子名称: PYRIDOXAL-5'-PHOSPHATE, SELENOCYSTEINE LYASE
著者Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2001-06-20
公開日2001-07-04
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Analysis of the E. coli NifS CsdB Protein at 2.0A Reveals the Structural Basis for Perselenide and Persulfide Intermediate Formation
J.Mol.Biol., 315, 2002
6UG7
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BU of 6ug7 by Molmil
Complex of ch28/11 Fab and SSEA-4 (tetragonal form)
分子名称: 1,2-ETHANEDIOL, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, SULFATE ION, ...
著者Soliman, C, Ramsland, P.A.
登録日2019-09-26
公開日2019-12-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody.
J.Biol.Chem., 295, 2020
5JNE
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BU of 5jne by Molmil
E2-SUMO-Siz1 E3-SUMO-PCNA complex
分子名称: E3 SUMO-protein ligase SIZ1,Ubiquitin-like protein SMT3, GLYCEROL, Proliferating cell nuclear antigen, ...
著者Lima, C.D, Streich Jr, F.C.
登録日2016-04-29
公開日2016-08-10
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Capturing a substrate in an activated RING E3/E2-SUMO complex.
Nature, 536, 2016
6BE2
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BU of 6be2 by Molmil
Crystal structure of a polysaccharide-binding human Fab (F598)
分子名称: Fab (F598) Heavy Chain, Fab (F598) Light Chain
著者Soliman, C, Ramsland, P.A.
登録日2017-10-24
公開日2018-02-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for antibody targeting of the broadly expressed microbial polysaccharide poly-N-acetylglucosamine.
J. Biol. Chem., 293, 2018
9B62
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BU of 9b62 by Molmil
Human RANBP2/RAN(GTP)/RANGAP1-SUMO1/UBC9/CRM1/RAN(GTP) - composite map and model
分子名称: E3 SUMO-protein ligase RanBP2, Exportin-1, GTP-binding nuclear protein Ran, ...
著者Lima, C.D, DiMattia, M.A.
登録日2024-03-23
公開日2024-10-16
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure and activities of a human RANBP2/RAN(GTP)/RANGAP1-SUMO1/UBC9/CRM1/RAN(GTP) complex
To Be Published
6BE3
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BU of 6be3 by Molmil
Crystal structure of a polysaccharide-binding human Fab (F598) in complex with N-acetyl-D-glucosamine (GlcNAc)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab (F598) Heavy Chain, Fab (F598) Light Chain
著者Soliman, C, Ramsland, P.A.
登録日2017-10-24
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for antibody targeting of the broadly expressed microbial polysaccharide poly-N-acetylglucosamine.
J. Biol. Chem., 293, 2018
1ECL
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BU of 1ecl by Molmil
AMINO TERMINAL 67KDA DOMAIN OF ESCHERICHIA COLI DNA TOPOISOMERASE I (RESIDUES 2-590 OF MATURE PROTEIN) CLONING ARTIFACT ADDS TWO RESIDUES TO THE AMINO-TERMINUS WHICH WERE NOT OBSERVED IN THE EXPERIMENTAL ELECTRON DENSITY (GLY-2, SER-1).
分子名称: ESCHERICHIA COLI TOPOISOMERASE I
著者Lima, C.D, Wang, J.C, Mondragon, A.
登録日1995-05-05
公開日1995-07-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I.
Nature, 367, 1994
1JR7
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CRYSTAL STRUCTURE OF GAB REVEALS OXIDOREDUCTASE FOLD
分子名称: FE (II) ION, HYPOTHETICAL 37.4 KDA PROTEIN IN ILEY-GABD INTERGENIC REGION
著者Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2001-08-12
公開日2001-08-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural genomics: a pipeline for providing structures for the biologist.
Protein Sci., 11, 2002
6UG9
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BU of 6ug9 by Molmil
Complex of ch28/11 Fab and SSEA-4 (hexagonal form)
分子名称: N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ch28/11 Fab heavy chain, ch28/11 Fab light chain
著者Soliman, C, Ramsland, P.A.
登録日2019-09-26
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody.
J.Biol.Chem., 295, 2020
3FIT
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BU of 3fit by Molmil
FHIT (FRAGILE HISTIDINE TRIAD PROTEIN) IN COMPLEX WITH ADENOSINE/SULFATE AMP ANALOG
分子名称: ADENOSINE MONOPHOSPHATE, FRAGILE HISTIDINE PROTEIN, SULFATE ION, ...
著者Lima, C.D, D'Amico, K.L, Naday, I, Rosenbaum, G, Westbrook, E.M, Hendrickson, W.A.
登録日1997-05-17
公開日1997-11-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family.
Structure, 5, 1997
6UGA
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BU of 6uga by Molmil
ch28/11 Fab (monoclinic form)
分子名称: ch28/11 Fab heavy chain, ch28/11 Fab light chain, methanesulfonic acid
著者Soliman, C, Ramsland, P.A.
登録日2019-09-26
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody.
J.Biol.Chem., 295, 2020
4PN0
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BU of 4pn0 by Molmil
Structure of S. pombe Pct1 RNA triphosphatase
分子名称: mRNA-capping enzyme subunit beta
著者Lima, C.D, Doamekpor, S.K.
登録日2014-05-22
公開日2014-11-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Fission yeast RNA triphosphatase reads an Spt5 CTD code.
Rna, 21, 2015
3KYC
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BU of 3kyc by Molmil
Human SUMO E1 complex with a SUMO1-AMP mimic
分子名称: 5'-deoxy-5'-(sulfamoylamino)adenosine, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ...
著者Lima, C.D.
登録日2009-12-05
公開日2010-02-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Active site remodelling accompanies thioester bond formation in the SUMO E1.
Nature, 463, 2010
3KYD
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BU of 3kyd by Molmil
Human SUMO E1~SUMO1-AMP tetrahedral intermediate mimic
分子名称: 1,2-ETHANEDIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, SUMO-activating enzyme subunit 1, ...
著者Lima, C.D.
登録日2009-12-05
公開日2010-02-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Active site remodelling accompanies thioester bond formation in the SUMO E1.
Nature, 463, 2010
3KYH
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BU of 3kyh by Molmil
Saccharomyces cerevisiae Cet1-Ceg1 capping apparatus
分子名称: mRNA-capping enzyme subunit alpha, mRNA-capping enzyme subunit beta
著者Lima, C.D.
登録日2009-12-06
公開日2010-02-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the Saccharomyces cerevisiae Cet1-Ceg1 mRNA Capping Apparatus.
Structure, 18, 2010
1RI6
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BU of 1ri6 by Molmil
Structure of a putative isomerase from E. coli
分子名称: putative isomerase ybhE
著者Lima, C.D, Kniewel, R, Solorzano, V, Wu, J, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2003-11-16
公開日2003-11-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a putative 7-bladed propeller isomerase
To be Published
4OO1
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BU of 4oo1 by Molmil
Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Exosome complex component CSL4, ...
著者Lima, C.D, Wasmuth, E.V.
登録日2014-01-29
公開日2014-07-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA.
Nature, 511, 2014
6U75
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BU of 6u75 by Molmil
Crystal Structure of S. Cerevisiae SUMO E3 Ligase SIZ2
分子名称: E3 SUMO-protein ligase SIZ2, ZINC ION
著者Lima, C.D, Cappadocia, L.
登録日2019-08-31
公開日2020-10-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献DNA asymmetry promotes SUMO modification of the single-stranded DNA-binding protein RPA.
Embo J., 40, 2021
1KPF
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BU of 1kpf by Molmil
PKCI-SUBSTRATE ANALOG
分子名称: ADENOSINE MONOPHOSPHATE, PROTEIN KINASE C INTERACTING PROTEIN
著者Lima, C.D, Klein, M.G, Hendrickson, W.A.
登録日1997-09-25
公開日1998-03-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based analysis of catalysis and substrate definition in the HIT protein family.
Science, 278, 1997
7KMY
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BU of 7kmy by Molmil
Structure of Mtb Lpd bound to 010705
分子名称: Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Lima, C.D.
登録日2020-11-03
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Whole Cell Active Inhibitors of Mycobacterial Lipoamide Dehydrogenase Afford Selectivity over the Human Enzyme through Tight Binding Interactions.
Acs Infect Dis., 7, 2021
2HV9
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BU of 2hv9 by Molmil
Encephalitozoon cuniculi mRNA Cap (Guanine-N7) Methyltransferase in complex with sinefungin
分子名称: SINEFUNGIN, mRNA cap guanine-N7 methyltransferase
著者Lima, C.D.
登録日2006-07-27
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mutational Analysis of Encephalitozoon cuniculi mRNA Cap (Guanine-N7) Methyltransferase, Structure of the Enzyme Bound to Sinefungin, and Evidence That Cap Methyltransferase Is the Target of Sinefungin's Antifungal Activity
J.Biol.Chem., 281, 2006
1KPE
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BU of 1kpe by Molmil
PKCI-TRANSITION STATE ANALOG
分子名称: ADENOSINE-5'-DITUNGSTATE, PROTEIN KINASE C INTERACTING PROTEIN
著者Lima, C.D, Klein, M.G, Hendrickson, W.A.
登録日1997-09-25
公開日1998-03-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-based analysis of catalysis and substrate definition in the HIT protein family.
Science, 278, 1997
1KPA
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BU of 1kpa by Molmil
PKCI-1-ZINC
分子名称: HUMAN PROTEIN KINASE C INTERACTING PROTEIN 1 (ZINC PROTEIN)
著者Lima, C.D, Klein, M.G, Weinstein, I.B, Hendrickson, W.A.
登録日1996-01-06
公開日1996-07-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteins.
Proc.Natl.Acad.Sci.USA, 93, 1996
1KPC
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PKCI-1-APO+ZINC
分子名称: HUMAN PROTEIN KINASE C INTERACTING PROTEIN 1 (ZINC PROTEIN)
著者Lima, C.D, Klein, M.G, Weinstein, I.B, Hendrickson, W.A.
登録日1996-01-06
公開日1996-07-11
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteins.
Proc.Natl.Acad.Sci.USA, 93, 1996

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