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5K36

Structure of an eleven component nuclear RNA exosome complex bound to RNA

Summary for 5K36
Entry DOI10.2210/pdb5k36/pdb
DescriptorExosome complex component RRP45, Exosome complex exonuclease RRP6, Exosome complex exonuclease DIS3, ... (16 entities in total)
Functional Keywordsexoribonuclease, complex, rna, structural protein, hydrolase-rna complex, hydrolase/rna
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
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Total number of polymer chains13
Total formula weight477520.40
Authors
Lima, C.D.,Zinder, J.C. (deposition date: 2016-05-19, release date: 2016-11-02, Last modification date: 2023-09-27)
Primary citationZinder, J.C.,Wasmuth, E.V.,Lima, C.D.
Nuclear RNA Exosome at 3.1 angstrom Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3.
Mol.Cell, 64:734-745, 2016
Cited by
PubMed: 27818140
DOI: 10.1016/j.molcel.2016.09.038
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.1 Å)
Structure validation

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