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PDB: 666 件
3NDM
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BU of 3ndm by Molmil
Crystal structure of Rho-Associated Protein Kinase (ROCK1) with a potent isoquinolone derivative
分子名称: (3S,4R)-N-(7-chloro-1-oxo-1,4-dihydroisoquinolin-6-yl)-4-(4-chlorophenyl)pyrrolidine-3-carboxamide, Rho-Associated Protein Kinase (ROCK1)
著者Li, X.
登録日2010-06-07
公開日2010-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 3, aryl substituted pyrrolidines.
Bioorg.Med.Chem.Lett., 20, 2010
1ZVF
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BU of 1zvf by Molmil
The crystal structure of 3-hydroxyanthranilate 3,4-dioxygenase from Saccharomyces cerevisiae
分子名称: 3-hydroxyanthranilate 3,4-dioxygenase, NICKEL (II) ION
著者Li, X, Guo, M, Teng, M, Niu, L.
登録日2005-06-02
公開日2006-06-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献The crystal structure of 3-hydroxyanthranilate 3,4-dioxygenase from Saccharomyces cerevisiae
To be published
8K2C
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BU of 8k2c by Molmil
Cryo-EM structure of the human 80S ribosome with Tigecycline
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Li, X, Wang, M, Cheng, J.
登録日2023-07-12
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
2DC2
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BU of 2dc2 by Molmil
Solution Structure of PDZ Domain
分子名称: golgi associated PDZ and coiled-coil motif containing isoform b
著者Li, X, Wu, J, Shi, Y.
登録日2005-12-20
公開日2006-09-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of GOPC PDZ domain and its interaction with the C-terminal motif of neuroligin
Protein Sci., 15, 2006
2FLU
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BU of 2flu by Molmil
Crystal Structure of the Kelch-Neh2 Complex
分子名称: Kelch-like ECH-associated protein 1, Nrf2
著者Li, X, Lo, J, Beamer, L, Hannink, M.
登録日2006-01-06
公開日2006-08-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling.
Embo J., 25, 2006
6A5K
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BU of 6a5k by Molmil
Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 1
分子名称: Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ...
著者Li, X, Du, J.
登録日2018-06-24
公開日2018-08-29
最終更新日2018-09-26
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6WL3
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BU of 6wl3 by Molmil
preTCRbeta-pMHC complex crystal structure
分子名称: ARG-GLY-TYR-LEU-TYR-GLN-GLY-LEU, H-2 class I histocompatibility antigen, K-B alpha chain, ...
著者Li, X, Mallis, R.J, Mizsei, R, Tan, K, Reinherz, E.L, Wang, J.
登録日2020-04-18
公開日2020-12-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Pre-T cell receptors topologically sample self-ligands during thymocyte beta-selection.
Science, 371, 2021
6WL2
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BU of 6wl2 by Molmil
preTCRbeta-pMHC complex crystal structure
分子名称: ARG-GLY-TYR-VAL-TYR-GLN-GLY-LEU, H-2 class I histocompatibility antigen, K-B alpha chain, ...
著者Li, X, Mallis, R.J, Mizsei, R, Tan, K, Reinherz, E.L, Wang, J.
登録日2020-04-18
公開日2020-12-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Pre-T cell receptors topologically sample self-ligands during thymocyte beta-selection.
Science, 371, 2021
6WL4
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BU of 6wl4 by Molmil
preTCRbeta-pMHC complex crystal structure
分子名称: ARG-GLY-TYR-VAL-TYR-GLN-GLY-LEU, H-2 class I histocompatibility antigen, K-B alpha chain, ...
著者Li, X, Mallis, R.J, Mizsei, R, Tan, K, Reinherz, E.L, Wang, J.
登録日2020-04-18
公開日2020-12-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Pre-T cell receptors topologically sample self-ligands during thymocyte beta-selection.
Science, 371, 2021
5H0S
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BU of 5h0s by Molmil
EM Structure of VP1A and VP1B
分子名称: VP1
著者Li, X, Zhou, N, Xu, B, Chen, W, Zhu, B, Wang, X, Wang, J, Liu, H, Cheng, L.
登録日2016-10-06
公開日2017-01-25
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Near-Atomic Resolution Structure Determination of a Cypovirus Capsid and Polymerase Complex Using Cryo-EM at 200kV
J. Mol. Biol., 429, 2017
8K2A
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BU of 8k2a by Molmil
Cryo-EM structure of the human 55S mitoribosome with Tigecycline
分子名称: 12S rRNA, 16S rRNA, 39S ribosomal protein L22, ...
著者Li, X, Wang, M, Cheng, J.
登録日2023-07-12
公開日2024-07-10
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8K2B
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BU of 8k2b by Molmil
Cryo-EM structure of the human 39S mitoribosome with Tigecycline
分子名称: 16s rRNA, 39S ribosomal protein L22, mitochondrial, ...
著者Li, X, Wang, M, Cheng, J.
登録日2023-07-12
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
5H0R
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BU of 5h0r by Molmil
RNA dependent RNA polymerase ,vp4,dsRNA
分子名称: RNA (42-MER), RNA-dependent RNA polymerase, VP4 protein
著者Li, X, Zhou, N, Chen, W, Zhu, B, Wang, X, Xu, B, Wang, J, Liu, H, Cheng, L.
登録日2016-10-06
公開日2017-01-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Near-Atomic Resolution Structure Determination of a Cypovirus Capsid and Polymerase Complex Using Cryo-EM at 200kV
J. Mol. Biol., 429, 2017
3L8J
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BU of 3l8j by Molmil
Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity
分子名称: Programmed cell death protein 10
著者Li, X, Zhang, R, Zhang, H, He, Y, Ji, W, Min, W, Boggon, T.J.
登録日2009-12-31
公開日2010-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity.
J.Biol.Chem., 285, 2010
3L8I
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BU of 3l8i by Molmil
Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity
分子名称: Programmed cell death protein 10
著者Li, X, Zhang, R, Zhang, H, He, Y, Ji, W, Min, W, Boggon, T.J.
登録日2009-12-31
公開日2010-05-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity.
J.Biol.Chem., 285, 2010
4EIR
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BU of 4eir by Molmil
Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases (PMO-2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, GLYCEROL, ...
著者Li, X, Beeson, W.T, Phillips, C.M, Marletta, M.A, Cate, J.H.
登録日2012-04-05
公開日2012-05-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases.
Structure, 20, 2012
4EIS
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BU of 4eis by Molmil
Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases (PMO-3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, PEROXIDE ION, ...
著者Li, X, Beeson, W.T, Phillips, C.M, Marletta, M.A, Cate, J.H.
登録日2012-04-05
公開日2012-05-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases.
Structure, 20, 2012
4QRD
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BU of 4qrd by Molmil
Structure of Methionyl-tRNA Synthetase in complex with N-(1H-benzimidazol-2-ylmethyl)-N'-(2,4-dichlorophenyl)-6-(morpholin-4-yl)-1,3,5-triazine-2,4-diamine
分子名称: MAGNESIUM ION, Methionyl-tRNA synthetase, N-(1H-benzimidazol-2-ylmethyl)-N'-(2,4-dichlorophenyl)-6-(morpholin-4-yl)-1,3,5-triazine-2,4-diamine
著者Li, X, Hilgers, M.T, Stidham, M, Brown-Driver, V, Shaw, K.J, Finn, J.
登録日2014-06-30
公開日2015-07-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Discovery and SAR of a Novel Series of Pyrimidine Antibacterials Targeting Methionyl-tRNA Synthetase
to be published
4QUV
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BU of 4quv by Molmil
Structure of an integral membrane delta(14)-sterol reductase
分子名称: Delta(14)-sterol reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Li, X, Blobel, G.
登録日2014-07-12
公開日2014-10-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.743 Å)
主引用文献Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum.
Nature, 517, 2015
4FWI
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BU of 4fwi by Molmil
Crystal structure of the nucleotide-binding domain of a dipeptide ABC transporter
分子名称: ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Li, X, Ge, J, Yang, M, Wang, N.
登録日2012-07-01
公開日2013-01-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.892 Å)
主引用文献Structure of the nucleotide-binding domain of a dipeptide ABC transporter reveals a novel iron-sulfur cluster-binding domain
Acta Crystallogr.,Sect.D, 69, 2013
5YGI
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BU of 5ygi by Molmil
Crystal structure of human FPPS in complex with an inhibitor THZ93
分子名称: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ...
著者Li, X.
登録日2017-09-23
公開日2018-09-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.177 Å)
主引用文献The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery.
Cell, 175, 2018
3UR1
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BU of 3ur1 by Molmil
The structure of a ternary complex between CheA domains P4 and P5 with CheW and with a truncated fragment of TM14, a chemoreceptor analog from Thermotoga maritima.
分子名称: Chemotaxis protein CheA, Chemotaxis protein CheW, Methyl-accepting chemotaxis protein
著者Li, X, Crane, B.R, Bilwes, A.M.
登録日2011-11-21
公開日2012-03-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献The structure of native bacterial chemoreceptor arrays
Proc.Natl.Acad.Sci.USA, 2012
3NCZ
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BU of 3ncz by Molmil
X-Ray Co-structure of Rho-Associated Protein Kinase (ROCK1) with a potent 2H-isoquinolin-1-one inhibitor
分子名称: Rho-associated protein kinase 1, cis-4-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)cyclohexanecarboxamide
著者Li, X.
登録日2010-06-06
公開日2010-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: Part 2, optimization for blood pressure reduction in spontaneously hypertensive rats.
Bioorg.Med.Chem.Lett., 20, 2010
4TVQ
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BU of 4tvq by Molmil
CCM3 in complex with CCM2 LD-like motif
分子名称: Cerebral cavernous malformations 2 protein, Cerebral cavernous malformations 3 protein
著者Li, X, Zhang, R, Fisher, O.S, Boggon, T.J.
登録日2014-06-27
公開日2015-03-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献CCM2-CCM3 interaction stabilizes their protein expression and permits endothelial network formation.
J.Cell Biol., 208, 2015
5INC
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BU of 5inc by Molmil
Crystal structure of HLA-B5801, a protective HLA allele for HIV-1 infection
分子名称: Beta-2-microglobulin, GLN-ALA-THR-GLN-GLU-VAL-LYS-ASN-TRP, HLA class I histocompatibility antigen, ...
著者Li, X, Wang, J.-H.
登録日2016-03-07
公開日2016-10-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.881 Å)
主引用文献Crystal structure of HLA-B*5801, a protective HLA allele for HIV-1 infection.
Protein Cell, 7, 2016

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件を2024-10-09に公開中

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