2IBM
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8K4L
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1QZD
| EF-Tu.kirromycin coordinates fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome | Descriptor: | Elongation factor Tu | Authors: | Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. | Deposit date: | 2003-09-16 | Release date: | 2003-11-04 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy Nat.Struct.Biol., 10, 2003
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1QZC
| Coordinates of S12, SH44, LH69 and SRL separately fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S12 | Authors: | Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. | Deposit date: | 2003-09-16 | Release date: | 2003-11-04 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy Nat.Struct.Biol., 10, 2003
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1QZB
| Coordinates of the A-site tRNA model fitted into the cryo-EM map of 70S ribosome in the pre-translocational state | Descriptor: | Phe-tRNA | Authors: | Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. | Deposit date: | 2003-09-16 | Release date: | 2003-11-04 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy Nat.Struct.Biol., 10, 2003
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1QZA
| Coordinates of the A/T site tRNA model fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome | Descriptor: | Phe-tRNA | Authors: | Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. | Deposit date: | 2003-09-16 | Release date: | 2003-11-04 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy Nat.Struct.Biol., 10, 2003
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1R2X
| Coordinates of L11 with 58nts of 23S rRNA fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome | Descriptor: | 50S ribosomal protein L11, 58nts of 23S rRNA | Authors: | Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. | Deposit date: | 2003-09-30 | Release date: | 2003-11-04 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron Microscopy Nat.Struct.Biol., 10, 2003
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1R2W
| Coordinates of L11 with 58nts of 23S rRNA fitted into the cryo-EM map of the 70S ribosome | Descriptor: | 50S ribosomal protein L11, 58nts of 23S rRNA | Authors: | Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. | Deposit date: | 2003-09-30 | Release date: | 2003-11-04 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron Microscopy Nat.Struct.Biol., 10, 2003
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6LOI
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4LAK
| Crystal structure of Cordyceps militaris IDCase D323N mutant in apo form | Descriptor: | Uracil-5-carboxylate decarboxylase, ZINC ION | Authors: | Xu, S, Li, W, Zhu, J, Wang, R, Li, Z, Xu, G.L, Ding, J. | Deposit date: | 2013-06-20 | Release date: | 2013-10-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase. Cell Res., 23, 2013
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2GD4
| Crystal Structure of the Antithrombin-S195A Factor Xa-Pentasaccharide Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, ... | Authors: | Johnson, D.J, Li, W, Adams, T.E, Huntington, J.A. | Deposit date: | 2006-03-15 | Release date: | 2006-05-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation. Embo J., 25, 2006
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7XKW
| The 3D strcuture of (-)-cyperene synthase with substrate analogue FSPP | Descriptor: | (-)-cyperene synthase, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE | Authors: | Yu, S.S, Zhu, P, Liu, Y.B, Ma, S.G, Ye, D, Shao, Y.Z, Li, W.R, Cui, Z.J. | Deposit date: | 2022-04-20 | Release date: | 2023-10-25 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Characterization and Engineering of Two Highly Paralogous Sesquiterpene Synthases Reveal a Regioselective Reprotonation Switch. Angew.Chem.Int.Ed.Engl., 63, 2024
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6BFU
| Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein, ... | Authors: | Xiong, X, Tortorici, M.A, Snijder, S, Yoshioka, C, Walls, A.C, Li, W, Seattle Structural Genomics Center for Infectious Disease (SSGCID), McGuire, A.T, Rey, F.A, Bosch, B.J, Veesler, D. | Deposit date: | 2017-10-27 | Release date: | 2017-11-22 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Glycan Shield and Fusion Activation of a Deltacoronavirus Spike Glycoprotein Fine-Tuned for Enteric Infections. J. Virol., 92, 2018
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8TGK
| VMAT1 dimer with histamine and reserpine | Descriptor: | Chromaffin granule amine transporter, HISTAMINE, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGH
| VMAT1 dimer with amphetamine and reserpine | Descriptor: | (2S)-1-phenylpropan-2-amine, Chromaffin granule amine transporter, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGN
| VMAT1 dimer with serotonin and reserpine | Descriptor: | Chromaffin granule amine transporter, SEROTONIN, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGG
| VMAT1 dimer with MPP+ and reserpine | Descriptor: | 1-methyl-4-phenylpyridin-1-ium, Chromaffin granule amine transporter, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGM
| VMAT1 dimer with reserpine | Descriptor: | VMAT1 dimer with reserpine, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGI
| VMAT1 dimer with dopamine and reserpine | Descriptor: | Chromaffin granule amine transporter, L-DOPAMINE, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGJ
| VMAT1 dimer in unbound form and with reserpine | Descriptor: | VMAT1 dimer in unbound form and with reserpine, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGL
| VMAT1 dimer with norepinephrine and reserpine | Descriptor: | Chromaffin granule amine transporter, L-NOREPINEPHRINE, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8J0K
| Crystal structure of human TFAP2A in complex with DNA | Descriptor: | DNA (5'-D(*CP*TP*GP*CP*CP*TP*CP*GP*GP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*CP*GP*AP*GP*GP*CP*AP*G)-3'), GLYCEROL, ... | Authors: | Liu, K, Xiao, Y.Q, Li, W.F, Min, J.R. | Deposit date: | 2023-04-11 | Release date: | 2023-07-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors. Nucleic Acids Res., 51, 2023
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3EQ4
| Model of tRNA(Leu)-EF-Tu in the ribosomal pre-accommodated state revealed by cryo-EM | Descriptor: | 30S ribosomal protein S12, 50S ribosomal protein L11, Elongation factor Tu, ... | Authors: | Frank, J, Li, W, Agirrezabala, X. | Deposit date: | 2008-09-30 | Release date: | 2008-12-16 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM. Embo J., 27, 2008
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6KZI
| Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine derivatives | Descriptor: | 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine, Serine/threonine-protein kinase pim-1 | Authors: | Zhang, W, Wan, X, Li, W, Xie, Y, Huang, N. | Deposit date: | 2019-09-24 | Release date: | 2020-03-04 | Last modified: | 2021-03-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors. J.Chem.Inf.Model., 60, 2020
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3EQ3
| Model of tRNA(Trp)-EF-Tu in the ribosomal pre-accommodated state revealed by cryo-EM | Descriptor: | 30S ribosomal protein S12, 50S ribosomal protein L11, Elongation factor Tu, ... | Authors: | Frank, J, Li, W, Agirrezabala, X. | Deposit date: | 2008-09-30 | Release date: | 2008-12-16 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM. Embo J., 27, 2008
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