8TGI
VMAT1 dimer with dopamine and reserpine
Summary for 8TGI
Entry DOI | 10.2210/pdb8tgi/pdb |
EMDB information | 41237 |
Descriptor | Chromaffin granule amine transporter, L-DOPAMINE, reserpine (3 entities in total) |
Functional Keywords | vmat, slc18, vascular monoamine transporter, monoamines, neurotransmitters, dopamine, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 101893.14 |
Authors | |
Primary citation | Ye, J.,Chen, H.,Wang, K.,Wang, Y.,Ammerman, A.,Awasthi, S.,Xu, J.,Liu, B.,Li, W. Structural insights into vesicular monoamine storage and drug interactions. Nature, 629:235-243, 2024 Cited by PubMed: 38499039DOI: 10.1038/s41586-024-07290-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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