5YWZ
 
 | | AID-SUN tandem of SUN1 | | 分子名称: | SUN domain-containing protein 1 | | 著者 | Xu, Y, Li, W, Feng, W. | | 登録日 | 2017-11-30 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural conservation of the autoinhibitory domain in SUN proteins
Biochem. Biophys. Res. Commun., 496, 2018
|
|
3SWH
 | |
2IBM
 | |
3UA0
 | | N-Terminal Domain of Bombyx mori Fibroin Mediates the Assembly of Silk in Response to pH Decrease | | 分子名称: | Fibroin heavy chain | | 著者 | He, Y.-X, Zhang, N.-N, Chen, B.-Y, Li, W.-F, Chen, Y.-X, Zhou, C.-Z. | | 登録日 | 2011-10-20 | | 公開日 | 2012-03-28 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | N-Terminal Domain of Bombyx mori Fibroin Mediates the Assembly of Silk in Response to pH Decrease.
J.Mol.Biol., 418, 2012
|
|
8ILR
 | | Cryo-EM structure of PI3Kalpha in complex with compound 16 | | 分子名称: | N-[(2S)-1-(ethylamino)-1-oxidanylidene-3-[4-(2-quinoxalin-6-ylethynyl)phenyl]propan-2-yl]-2,3-dimethyl-quinoxaline-6-carboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | | 著者 | Zhou, Q, Liu, X, Neri, D, Li, W, Favalli, N, Bassi, G, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W. | | 登録日 | 2023-03-04 | | 公開日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Structural insights into the interaction of three Y-shaped ligands with PI3K alpha.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8ILS
 | | Cryo-EM structure of PI3Kalpha in complex with compound 17 | | 分子名称: | N-[(2R)-1-(ethylamino)-1-oxidanylidene-3-[4-(2-quinoxalin-6-ylethynyl)phenyl]propan-2-yl]-2,3-dimethyl-quinoxaline-6-carboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | | 著者 | Zhou, Q, Liu, X, Neri, D, Li, W, Favalli, N, Bassi, G, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W. | | 登録日 | 2023-03-04 | | 公開日 | 2023-09-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural insights into the interaction of three Y-shaped ligands with PI3K alpha.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
4NV2
 | | C50A mutant of Synechococcus VKOR, C2221 crystal form | | 分子名称: | UBIQUINONE-10, VKORC1/thioredoxin domain protein | | 著者 | Liu, S, Cheng, W, Fowle Grider, R, Shen, G, Li, W. | | 登録日 | 2013-12-04 | | 公開日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (3.61 Å) | | 主引用文献 | Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer.
Nat Commun, 5, 2014
|
|
4NV6
 | | C212A mutant of Synechococcus VKOR | | 分子名称: | UBIQUINONE-10, VKORC1/thioredoxin domain protein | | 著者 | Liu, S, Cheng, W, Fowle Grider, R, Shen, G, Li, W. | | 登録日 | 2013-12-04 | | 公開日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (4.19 Å) | | 主引用文献 | Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer.
Nat Commun, 5, 2014
|
|
8J0Q
 | | Structure of DNA binding domain of human TFAP2B | | 分子名称: | GLYCEROL, Transcription factor AP-2-beta | | 著者 | Liu, K, Xiao, Y.Q, Li, W.F, Min, J.R. | | 登録日 | 2023-04-11 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors.
Nucleic Acids Res., 51, 2023
|
|
8J0R
 | | Structure of human TFAP2A in complex with DNA | | 分子名称: | DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*TP*GP*CP*CP*TP*CP*AP*GP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*GP*AP*GP*GP*CP*AP*G)-3'), ... | | 著者 | Liu, K, Xiao, Y.Q, Li, W.F, Min, J.R. | | 登録日 | 2023-04-11 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors.
Nucleic Acids Res., 51, 2023
|
|
6BFU
 | | Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein, ... | | 著者 | Xiong, X, Tortorici, M.A, Snijder, S, Yoshioka, C, Walls, A.C, Li, W, Seattle Structural Genomics Center for Infectious Disease (SSGCID), McGuire, A.T, Rey, F.A, Bosch, B.J, Veesler, D. | | 登録日 | 2017-10-27 | | 公開日 | 2017-11-22 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Glycan Shield and Fusion Activation of a Deltacoronavirus Spike Glycoprotein Fine-Tuned for Enteric Infections.
J. Virol., 92, 2018
|
|
4L16
 | | Crystal structure of FIGL-1 AAA domain in complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Fidgetin-like protein 1 | | 著者 | Peng, W, Lin, Z, Li, W, Lu, J, Shen, Y, Wang, C. | | 登録日 | 2013-06-02 | | 公開日 | 2013-09-04 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural insights into the unusually strong ATPase activity of the AAA domain of the Caenorhabditis elegans fidgetin-like 1 (FIGL-1) protein.
J.Biol.Chem., 288, 2013
|
|
4L15
 | | Crystal structure of FIGL-1 AAA domain | | 分子名称: | Fidgetin-like protein 1, TRIS(HYDROXYETHYL)AMINOMETHANE | | 著者 | Peng, W, Lin, Z, Li, W, Lu, J, Shen, Y, Wang, C. | | 登録日 | 2013-06-02 | | 公開日 | 2013-09-04 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural insights into the unusually strong ATPase activity of the AAA domain of the Caenorhabditis elegans fidgetin-like 1 (FIGL-1) protein.
J.Biol.Chem., 288, 2013
|
|
4QAU
 | |
8K4L
 | |
4NV5
 | | C50A mutant of Synechococcus VKOR, C2 crystal form (dehydrated) | | 分子名称: | UBIQUINONE-10, VKORC1/thioredoxin domain protein | | 著者 | Liu, S, Cheng, W, Fowle Grider, R, Shen, G, Li, W. | | 登録日 | 2013-12-04 | | 公開日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer.
Nat Commun, 5, 2014
|
|
8ILV
 | | Cryo-EM structure of PI3Kalpha in complex with compound 18 | | 分子名称: | N-[(2R)-1-(ethylamino)-1-oxidanylidene-3-[3-(2-quinoxalin-6-ylethynyl)phenyl]propan-2-yl]-2,3-dimethyl-quinoxaline-6-carboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | | 著者 | Zhou, Q, Liu, X, Neri, D, Li, W, Favalli, N, Bassi, G, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W. | | 登録日 | 2023-03-04 | | 公開日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Structural insights into the interaction of three Y-shaped ligands with PI3K alpha.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
3EQ4
 | | Model of tRNA(Leu)-EF-Tu in the ribosomal pre-accommodated state revealed by cryo-EM | | 分子名称: | 30S ribosomal protein S12, 50S ribosomal protein L11, Elongation factor Tu, ... | | 著者 | Frank, J, Li, W, Agirrezabala, X. | | 登録日 | 2008-09-30 | | 公開日 | 2008-12-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (12 Å) | | 主引用文献 | Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM.
Embo J., 27, 2008
|
|
3EQ3
 | | Model of tRNA(Trp)-EF-Tu in the ribosomal pre-accommodated state revealed by cryo-EM | | 分子名称: | 30S ribosomal protein S12, 50S ribosomal protein L11, Elongation factor Tu, ... | | 著者 | Frank, J, Li, W, Agirrezabala, X. | | 登録日 | 2008-09-30 | | 公開日 | 2008-12-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM.
Embo J., 27, 2008
|
|
3HIA
 | | Crystal structure of the choline binding domain of Spr1274 in Streptococcus pneumoniae | | 分子名称: | Choline binding protein, PHOSPHOCHOLINE, SULFATE ION | | 著者 | Zhang, Z.-Y, Li, W.-Z, Jiang, Y.-L, Bao, R, Zhou, C.-Z, Chen, Y.-X. | | 登録日 | 2009-05-19 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Crystal structure of the choline binding domain of Spr1274 in Streptococcus pneumoniae
To be Published
|
|
4IJC
 | | Crystal structure of arabinose dehydrogenase Ara1 from Saccharomyces cerevisiae | | 分子名称: | D-arabinose dehydrogenase [NAD(P)+] heavy chain, GLYCEROL, SULFATE ION | | 著者 | Hu, X.Q, Guo, P.C, Li, W.F, Zhou, C.Z. | | 登録日 | 2012-12-21 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures of Saccharomyces cerevisiaeD-arabinose dehydrogenase Ara1 and its complex with NADPH: implications for cofactor-assisted substrate recognition
Acta Crystallogr.,Sect.F, 69, 2013
|
|
4IJR
 | | Crystal structure of Saccharomyces cerevisiae arabinose dehydrogenase Ara1 complexed with NADPH | | 分子名称: | D-arabinose dehydrogenase [NAD(P)+] heavy chain, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Hu, X.Q, Guo, P.C, Li, W.F, Zhou, C.Z. | | 登録日 | 2012-12-23 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of Saccharomyces cerevisiaeD-arabinose dehydrogenase Ara1 and its complex with NADPH: implications for cofactor-assisted substrate recognition
Acta Crystallogr.,Sect.F, 69, 2013
|
|
5XHC
 | | Crystal structure of T2R-TTL-PO10 complex | | 分子名称: | (3Z,6Z)-3-[(4-tert-butyl-1H-imidazol-5-yl)methylidene]-6-[[3-(4-fluorophenyl)carbonylphenyl]methylidene]piperazine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Chu, Y, Wang, Y, Yang, J, Li, W. | | 登録日 | 2017-04-20 | | 公開日 | 2017-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Synthesis, biological evaluation and X-ray structure of anti-microtubule agents
To Be Published
|
|
5XI5
 | | Crystal structure of T2R-TTL-PO5 complex | | 分子名称: | (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Chu, Y, Wang, Y, Yang, J, Li, W. | | 登録日 | 2017-04-26 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Synthesis, biological evaluation and X-ray structure of anti-microtubule agents
To Be Published
|
|
4DY0
 | | Crystal structure of native protease nexin-1 with heparin | | 分子名称: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, GLYCEROL, Glia-derived nexin, ... | | 著者 | Huntington, J.A, Li, W. | | 登録日 | 2012-02-28 | | 公開日 | 2012-08-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism.
Blood, 120, 2012
|
|
