8J0R

Structure of human TFAP2A in complex with DNA

Summary for 8J0R

• Entry DOI: 10.2210/pdb8j0r/pdb
• Descriptor: Transcription factor AP-2-alpha, DNA (5'-D(*CP*TP*GP*CP*CP*TP*CP*AP*GP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*GP*AP*GP*GP*CP*AP*G)-3'), ... (8 entities in total)
• Functional Keywords: tfap2 family, dna binding protein/dna, dna binding protein-dna complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 56869.29

Authors

Liu, K.,Xiao, Y.Q.,Li, W.F.,Min, J.R. (deposition date: 2023-04-11, release date: 2023-07-05, Last modification date: 2023-09-06)

• Primary citation: Liu, K.,Xiao, Y.,Gan, L.,Li, W.,Zhang, J.,Min, J.; Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors.; Nucleic Acids Res., 51:8270-8282, 2023; PubMed: 37409559; DOI: 10.1093/nar/gkad583

Experimental method

X-RAY DIFFRACTION (2.1 Å)