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PDB: 157 件
6O8B
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BU of 6o8b by Molmil
Crystal structure of STING CTD in complex with TBK1
分子名称: N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein
著者Li, P, Zhao, B, Du, F.
登録日2019-03-09
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature, 569, 2019
4LEY
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BU of 4ley by Molmil
Structure of mouse cGAS bound to 18 bp DNA
分子名称: 18 bp dsDNA, Cyclic GMP-AMP synthase, ZINC ION
著者Li, P.
登録日2013-06-26
公開日2013-12-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization.
Immunity, 39, 2013
3GA3
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BU of 3ga3 by Molmil
Crystal structure of the C-terminal domain of human MDA5
分子名称: Interferon-induced helicase C domain-containing protein 1, MDA5, ZINC ION
著者Li, P.
登録日2009-02-16
公開日2009-02-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of the C-terminal domain of human MDA5
To be Published
5JEJ
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BU of 5jej by Molmil
Phosphorylated STING in complex with IRF-3 CTD
分子名称: Interferon regulatory factor 3, Stimulator of interferon genes protein
著者Li, P, Shu, C.
登録日2016-04-18
公開日2016-06-15
最終更新日2016-06-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
2OTU
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BU of 2otu by Molmil
Crystal structure of Fv polyglutamine complex
分子名称: Fv heavy chain variable domain, Fv light chain variable domain, peptide antigen
著者Li, P.
登録日2007-02-09
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Implications of the structure of a poly-Gln/anti-poly-Gln complex for disease progression and therapy
To be Published
3LRR
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BU of 3lrr by Molmil
Crystal structure of human RIG-I CTD bound to a 12 bp AU rich 5' ppp dsRNA
分子名称: Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(ATP)P*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*U)-3'), ZINC ION
著者Li, P.
登録日2010-02-11
公開日2010-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Structure, 18, 2010
6J76
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BU of 6j76 by Molmil
Structure of 3,6-anhydro-L-galactose Dehydrogenase in Complex with NAP
分子名称: Aldehyde dehydrogenase A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Li, P.Y, Wang, Y, Chen, X.L, Zhang, Y.Z.
登録日2019-01-17
公開日2020-01-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.368 Å)
主引用文献3,6-Anhydro-L-Galactose Dehydrogenase VvAHGD is a Member of a New Aldehyde Dehydrogenase Family and Catalyzes by a Novel Mechanism with Conformational Switch of Two Catalytic Residues Cysteine 282 and Glutamate 248.
J.Mol.Biol., 432, 2020
4LEW
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BU of 4lew by Molmil
Structure of human cGAS
分子名称: Cyclic GMP-AMP synthase, ZINC ION
著者Li, P.
登録日2013-06-26
公開日2013-12-25
最終更新日2014-01-08
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization.
Immunity, 39, 2013
2OTW
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BU of 2otw by Molmil
Crystal structure of Fv polyglutamine complex
分子名称: Fv heavy chain variable domain VH, Fv light chain avriable domain VL, poly-Gln peptide antigen
著者Li, P.
登録日2007-02-09
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Implications of the structure of a poly-Gln/anti-poly-Gln complex for disease progression and therapy
To be Published
1JFM
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BU of 1jfm by Molmil
CRYSTAL STRUCTURE OF MURINE NK CELL LIGAND RAE-1 BETA
分子名称: retinoic acid early transcript beta
著者Li, P, Strong, R.K.
登録日2001-06-21
公開日2002-02-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D.
Immunity, 16, 2002
6J75
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BU of 6j75 by Molmil
Structure of 3,6-anhydro-L-galactose Dehydrogenase
分子名称: Aldehyde dehydrogenase A
著者Li, P.Y, Wang, Y, Chen, X.L, Zhang, Y.Z.
登録日2019-01-17
公開日2020-01-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.695 Å)
主引用文献3,6-Anhydro-L-Galactose Dehydrogenase VvAHGD is a Member of a New Aldehyde Dehydrogenase Family and Catalyzes by a Novel Mechanism with Conformational Switch of Two Catalytic Residues Cysteine 282 and Glutamate 248.
J.Mol.Biol., 432, 2020
5X1T
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BU of 5x1t by Molmil
PpkA-294
分子名称: ADENOSINE-5'-DIPHOSPHATE, PpkA-294
著者Li, P.P, Ran, T.T, Xu, D.Q, Wang, W.W.
登録日2017-01-26
公開日2018-01-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of the kinase domain of PpkA, a key regulatory component of T6SS, reveal a general inhibitory mechanism.
Biochem.J., 475, 2018
5X1Q
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PpkA-294 with ATP and MnCl2
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ...
著者Li, P.P, Ran, T.T, Xu, D.Q, Wang, W.W.
登録日2017-01-26
公開日2018-01-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Crystal structures of the kinase domain of PpkA, a key regulatory component of T6SS, reveal a general inhibitory mechanism.
Biochem.J., 475, 2018
5X1S
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BU of 5x1s by Molmil
PpkA-294 with Amppcp
分子名称: GLYCEROL, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, PpkA
著者Li, P.P, Ran, T.T, Xu, D.Q, Wang, W.W.
登録日2017-01-26
公開日2018-01-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structures of the kinase domain of PpkA, a key regulatory component of T6SS, reveal a general inhibitory mechanism.
Biochem.J., 475, 2018
7JFM
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BU of 7jfm by Molmil
Crystal structure of mouse phosphorylated IRF-3 bound to CBP
分子名称: CREB-binding protein, Interferon regulatory factor 3
著者Li, P, Jing, T, Zhao, B.
登録日2020-07-17
公開日2020-09-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献The Structural Basis of IRF-3 Activation upon Phosphorylation.
J Immunol., 205, 2020
7JFL
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BU of 7jfl by Molmil
Crystal structure of human phosphorylated IRF-3 bound to CBP
分子名称: CREB-binding protein, Interferon regulatory factor 3
著者Li, P, Jing, T, Zhao, B.
登録日2020-07-17
公開日2020-09-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献The Structural Basis of IRF-3 Activation upon Phosphorylation.
J Immunol., 205, 2020
3OG8
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BU of 3og8 by Molmil
Crystal structure of human RIG-I CTD bound to a 14-bp blunt-ended dsRNA
分子名称: Antiviral innate immune response receptor RIG-I, RNA (5'-R(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION
著者Li, P.
登録日2010-08-16
公開日2010-11-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate.
Nucleic Acids Res., 39, 2011
4LEV
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BU of 4lev by Molmil
Structure of human cGAS
分子名称: Cyclic GMP-AMP synthase, ZINC ION
著者Li, P.
登録日2013-06-26
公開日2013-12-25
最終更新日2014-01-08
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization.
Immunity, 39, 2013
3E3H
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BU of 3e3h by Molmil
Crystal structure of the OP hydrolase mutant from Brevundimonas diminuta
分子名称: COBALT (II) ION, DIETHYL 4-METHYLBENZYLPHOSPHONATE, Parathion hydrolase
著者Li, P, Reeves, T.E, Grimsley, J.K, Wild, J.R.
登録日2008-08-07
公開日2008-10-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Balancing the stability and the catalytic specificities of OP hydrolases with enhanced V-agent activities.
Protein Eng.Des.Sel., 21, 2008
5WSO
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BU of 5wso by Molmil
crystal structure of BVDV NS3 helicase
分子名称: NS3 helicase
著者Li, P, Shi, J, Wang, S, Li, S, Mao, X.
登録日2016-12-08
公開日2017-12-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Crystal structure of BVDV NS3 helicase
To Be Published
1B3J
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BU of 1b3j by Molmil
STRUCTURE OF THE MHC CLASS I HOMOLOG MIC-A, A GAMMADELTA T CELL LIGAND
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS I HOMOLOG MIC-A
著者Li, P, Willie, S, Bauer, S, Morris, D, Spies, T, Strong, R.
登録日1998-12-11
公開日1999-07-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the MHC class I homolog MIC-A, a gammadelta T cell ligand.
Immunity, 10, 1999
5V5F
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BU of 5v5f by Molmil
Crystal structure of RICE1 (PNT2)
分子名称: At3g11770
著者Li, P.
登録日2017-03-14
公開日2017-09-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.945 Å)
主引用文献RISC-interacting clearing 3'- 5' exoribonucleases (RICEs) degrade uridylated cleavage fragments to maintain functional RISC in Arabidopsis thaliana.
Elife, 6, 2017
3S2X
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BU of 3s2x by Molmil
Structure of acetyl-Coenzyme A synthase Alpha subunit C-terminal domain
分子名称: NICKEL (II) ION, acetyl-CoA synthase subunit alpha
著者Li, P.
登録日2011-05-17
公開日2011-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Insights into the Mechanistic Role of the [Fe(4) S(4) ] Cubane in the A-Cluster {[Fe(4) S(4) ]-(SR)-[Ni(p) Ni(d) ]} of Acetyl-Coenzyme A Synthase.
Chembiochem, 12, 2011
3U9M
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BU of 3u9m by Molmil
Structure of reduced human FBXL5 hemerythrin like domain
分子名称: F-box/LRR-repeat protein 5, FE (III) ION
著者Li, P.
登録日2011-10-19
公開日2012-02-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Structural Basis of Iron Sensing by the Human F-box Protein FBXL5.
Chembiochem, 13, 2012
4EMT
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BU of 4emt by Molmil
Crystal Structure of human STING bound to c-di-GMP
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173
著者Li, P.
登録日2012-04-12
公開日2012-06-13
最終更新日2012-07-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system.
Nat.Struct.Mol.Biol., 19, 2012

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