7JFL

Crystal structure of human phosphorylated IRF-3 bound to CBP

Summary for 7JFL

• Entry DOI: 10.2210/pdb7jfl/pdb
• Descriptor: Interferon regulatory factor 3, CREB-binding protein (3 entities in total)
• Functional Keywords: transcription factor, phosphorylation, innate immunity, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 58090.01

Authors

Li, P.,Jing, T.,Zhao, B. (deposition date: 2020-07-17, release date: 2020-09-09, Last modification date: 2023-10-18)

• Primary citation: Jing, T.,Zhao, B.,Xu, P.,Gao, X.,Chi, L.,Han, H.,Sankaran, B.,Li, P.; The Structural Basis of IRF-3 Activation upon Phosphorylation.; J Immunol., 205:1886-1896, 2020; PubMed: 32826280; DOI: 10.4049/jimmunol.2000026

Experimental method

X-RAY DIFFRACTION (1.68 Å)