8X5I
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8X51
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![BU of 8x51 by Molmil](/molmil-images/mine/8x51) | Cryo-EM structure of Gabija GajA in complex with DNA(focused refinement) | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*TP*T)-3'), ... | 著者 | Li, J, Wang, Z, Wang, L. | 登録日 | 2023-11-16 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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8WY5
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![BU of 8wy5 by Molmil](/molmil-images/mine/8wy5) | Structure of Gabija GajA in complex with DNA | 分子名称: | CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*T)-3'), ... | 著者 | Li, J, Wang, Z, Wang, L. | 登録日 | 2023-10-30 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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5XBF
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![BU of 5xbf by Molmil](/molmil-images/mine/5xbf) | Crystal Structure of Myo7b C-terminal MyTH4-FERM in complex with USH1C PDZ3 | 分子名称: | ACETATE ION, D-MALATE, GLYCEROL, ... | 著者 | Li, J, He, Y, Weck, W.L, Lu, Q, Tyska, M.J, Zhang, M. | 登録日 | 2017-03-17 | 公開日 | 2017-05-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5WSV
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![BU of 5wsv by Molmil](/molmil-images/mine/5wsv) | Crystal structure of Myosin VIIa IQ5 in complex with Ca2+-CaM | 分子名称: | CALCIUM ION, Calmodulin, SULFATE ION, ... | 著者 | Li, J, Chen, Y, Deng, Y, Lu, Q, Zhang, M. | 登録日 | 2016-12-08 | 公開日 | 2017-06-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Ca(2+)-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single alpha Helix Lever Arm Extension Structure, 25, 2017
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4M2S
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![BU of 4m2s by Molmil](/molmil-images/mine/4m2s) | Corrected Structure of Mouse P-glycoprotein bound to QZ59-RRR | 分子名称: | (4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1A | 著者 | Li, J, Jaimes, K.F, Aller, S.G. | 登録日 | 2013-08-05 | 公開日 | 2013-11-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | 主引用文献 | Refined structures of mouse P-glycoprotein. Protein Sci., 23, 2014
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4M1M
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7CFU
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7CDB
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![BU of 7cdb by Molmil](/molmil-images/mine/7cdb) | Structure of GABARAPL1 in complex with GABA(A) receptor gamma 2 | 分子名称: | ACETATE ION, CITRIC ACID, Gamma-aminobutyric acid receptor subunit gamma-2, ... | 著者 | Li, J, Ye, J, Zhu, R, Kong, C, Zhang, M, Wang, C. | 登録日 | 2020-06-19 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | 主引用文献 | Structural basis of GABARAP-mediated GABA A receptor trafficking and functions on GABAergic synaptic transmission. Nat Commun, 12, 2021
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7C6P
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![BU of 7c6p by Molmil](/molmil-images/mine/7c6p) | Bromodomain-containing 4 BD2 in complex with 3',4',7,8- Tetrahydroxyflavonoid | 分子名称: | 2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one, Bromodomain-containing protein 4 | 著者 | Li, J, Yu, K, Luo, Y, Zheng, W, Liang, W, Zhu, J. | 登録日 | 2020-05-22 | 公開日 | 2021-05-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor. J Enzyme Inhib Med Chem, 36, 2021
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7C2Z
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![BU of 7c2z by Molmil](/molmil-images/mine/7c2z) | Bromodomain-containing 4 BD1 in complex with 3',4',7,8-Tetrahydroxyflavone | 分子名称: | 2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one, Bromodomain-containing protein 4, FORMIC ACID | 著者 | Li, J, Zhu, J. | 登録日 | 2020-05-10 | 公開日 | 2021-05-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor. J Enzyme Inhib Med Chem, 36, 2021
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7DVM
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5YIS
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![BU of 5yis by Molmil](/molmil-images/mine/5yis) | Crystal Structure of AnkB LIR/LC3B complex | 分子名称: | Ankyrin-2, GLYCEROL, Microtubule-associated proteins 1A/1B light chain 3B, ... | 著者 | Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M. | 登録日 | 2017-10-06 | 公開日 | 2018-05-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins. Nat. Chem. Biol., 14, 2018
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5YIQ
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![BU of 5yiq by Molmil](/molmil-images/mine/5yiq) | Crystal structure of AnkG LIR/LC3B complex | 分子名称: | Ankyrin-3, Microtubule-associated proteins 1A/1B light chain 3B, ZINC ION | 著者 | Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M. | 登録日 | 2017-10-06 | 公開日 | 2018-05-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins. Nat. Chem. Biol., 14, 2018
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5YIR
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![BU of 5yir by Molmil](/molmil-images/mine/5yir) | Crystal Structure of AnkB LIR/GABARAP complex | 分子名称: | Ankyrin-2, Gamma-aminobutyric acid receptor-associated protein, NICKEL (II) ION | 著者 | Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M. | 登録日 | 2017-10-06 | 公開日 | 2018-05-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins. Nat. Chem. Biol., 14, 2018
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6JLS
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![BU of 6jls by Molmil](/molmil-images/mine/6jls) | Crystal Structure of FMN-dependent Cysteine Decarboxylases TvaF from Thioviridamide Biosynthesis | 分子名称: | FLAVIN MONONUCLEOTIDE, Putative flavoprotein decarboxylase | 著者 | Li, J, Lu, J, Wang, H, Zhu, J. | 登録日 | 2019-03-06 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Characterization of the FMN-Dependent Cysteine Decarboxylase from Thioviridamide Biosynthesis. Org.Lett., 21, 2019
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5YIP
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![BU of 5yip by Molmil](/molmil-images/mine/5yip) | Crystal Structure of AnkG LIR/GABARAPL1 complex | 分子名称: | Ankyrin-3, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein-like 1 | 著者 | Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M. | 登録日 | 2017-10-06 | 公開日 | 2018-05-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins. Nat. Chem. Biol., 14, 2018
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8W6I
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8W6J
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![BU of 8w6j by Molmil](/molmil-images/mine/8w6j) | Cryo-EM structure of Escherichia coli Str K12 FtsE(E163Q)X/EnvC complex with ATP in peptidisc | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | 著者 | Li, J, Xu, X, He, Y, Luo, M. | 登録日 | 2023-08-29 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of Escherichia coli Str K12 FtsE(E163Q)X/EnvC complex with ATP in peptidisc To Be Published
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7CUQ
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![BU of 7cuq by Molmil](/molmil-images/mine/7cuq) | 2.55-Angstrom Cryo-EM structure of Cytochrome bo3 from Escherichia coli in Native Membrane | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | 著者 | Li, J, Han, L, Gennis, R.B, Zhu, J.P, Zhang, K. | 登録日 | 2020-08-24 | 公開日 | 2021-08-25 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | 主引用文献 | Cryo-EM structures of Escherichia coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site. Proc.Natl.Acad.Sci.USA, 118, 2021
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7CUW
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![BU of 7cuw by Molmil](/molmil-images/mine/7cuw) | Ubiquinol Binding Site of Cytochrome bo3 from Escherichia coli | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | 著者 | Li, J, Han, L, Gennis, R.B, Zhu, J.P, Zhang, K. | 登録日 | 2020-08-25 | 公開日 | 2021-08-25 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | 主引用文献 | Cryo-EM structures of Escherichia coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site. Proc.Natl.Acad.Sci.USA, 118, 2021
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7CUB
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![BU of 7cub by Molmil](/molmil-images/mine/7cub) | 2.55-Angstrom Cryo-EM structure of Cytochrome bo3 from Escherichia coli in Native Membrane | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | 著者 | Li, J, Han, L, Gennis, R.B, Zhu, J.P, Zhang, K. | 登録日 | 2020-08-22 | 公開日 | 2021-08-25 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | 主引用文献 | Cryo-EM structures of Escherichia coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site. Proc.Natl.Acad.Sci.USA, 118, 2021
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8UOZ
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![BU of 8uoz by Molmil](/molmil-images/mine/8uoz) | EmrE structure in the TPP-bound state (WT/E14Q heterodimer) | 分子名称: | SMR family multidrug efflux protein EmrE, TETRAPHENYLPHOSPHONIUM | 著者 | Li, J, Sae Her, A, Besch, A, Ramirez, B, Crames, M, Banigan, J.R, Mueller, C, Marsiglia, W.M, Zhang, Y, Traaseth, N.J. | 登録日 | 2023-10-20 | 公開日 | 2024-05-29 | 最終更新日 | 2024-07-03 | 実験手法 | SOLID-STATE NMR, SOLUTION NMR | 主引用文献 | Dynamics underlie the drug recognition mechanism by the efflux transporter EmrE. Nat Commun, 15, 2024
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6LDZ
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![BU of 6ldz by Molmil](/molmil-images/mine/6ldz) | Crystal structure of Rv0222 from Mycobacterium tuberculosis | 分子名称: | Probable enoyl-CoA hydratase EchA1 (Enoyl hydrase) (Unsaturated acyl-CoA hydratase) (Crotonase) | 著者 | Li, J, Ran, Y.J, Wang, L, Wu, J.H, Ge, B.X, Rao, Z.H. | 登録日 | 2019-11-23 | 公開日 | 2020-01-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Host-mediated ubiquitination of a mycobacterial protein suppresses immunity. Nature, 577, 2020
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8UWU
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![BU of 8uwu by Molmil](/molmil-images/mine/8uwu) | EmrE structure in the proton-bound state (WT/L51I heterodimer) | 分子名称: | SMR family multidrug efflux protein EmrE | 著者 | Li, J, Sae Her, A, Besch, A, Ramirez, B, Crames, M, Banigan, J.R, Mueller, C, Marsiglia, W.M, Zhang, Y, Traaseth, N.J. | 登録日 | 2023-11-08 | 公開日 | 2024-05-29 | 最終更新日 | 2024-07-03 | 実験手法 | SOLID-STATE NMR, SOLUTION NMR | 主引用文献 | Dynamics underlie the drug recognition mechanism by the efflux transporter EmrE. Nat Commun, 15, 2024
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