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PDB: 833 件

8X5I
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tetramer Gabija with ATP (local refinement)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA, MAGNESIUM ION
著者Li, J, Wang, Z, Wang, L.
登録日2023-11-17
公開日2024-02-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8X51
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Cryo-EM structure of Gabija GajA in complex with DNA(focused refinement)
分子名称: CALCIUM ION, DNA (5'-D(*AP*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*TP*T)-3'), ...
著者Li, J, Wang, Z, Wang, L.
登録日2023-11-16
公開日2024-02-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8WY5
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Structure of Gabija GajA in complex with DNA
分子名称: CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*T)-3'), ...
著者Li, J, Wang, Z, Wang, L.
登録日2023-10-30
公開日2024-02-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
5XBF
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Crystal Structure of Myo7b C-terminal MyTH4-FERM in complex with USH1C PDZ3
分子名称: ACETATE ION, D-MALATE, GLYCEROL, ...
著者Li, J, He, Y, Weck, W.L, Lu, Q, Tyska, M.J, Zhang, M.
登録日2017-03-17
公開日2017-05-17
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WSV
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Crystal structure of Myosin VIIa IQ5 in complex with Ca2+-CaM
分子名称: CALCIUM ION, Calmodulin, SULFATE ION, ...
著者Li, J, Chen, Y, Deng, Y, Lu, Q, Zhang, M.
登録日2016-12-08
公開日2017-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Ca(2+)-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single alpha Helix Lever Arm Extension
Structure, 25, 2017
4M2S
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Corrected Structure of Mouse P-glycoprotein bound to QZ59-RRR
分子名称: (4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1A
著者Li, J, Jaimes, K.F, Aller, S.G.
登録日2013-08-05
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Refined structures of mouse P-glycoprotein.
Protein Sci., 23, 2014
4M1M
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Corrected Structure of Mouse P-glycoprotein
分子名称: MERCURY (II) ION, Multidrug resistance protein 1A
著者Li, J, Jaimes, K.F, Aller, S.G.
登録日2013-08-03
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Refined structures of mouse P-glycoprotein.
Protein Sci., 23, 2014
7CFU
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Crystal Structure of FMN-dependent Cysteine Decarboxylases SpaF
分子名称: ARGININE, DNA/pantothenate metabolism flavoprotein, FLAVIN MONONUCLEOTIDE
著者Li, J, Lu, J, Wang, H, Zhu, J.
登録日2020-06-28
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Characterization of FMN-dependent Cysteine Decarboxylases SPAF
To Be Published
7CDB
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Structure of GABARAPL1 in complex with GABA(A) receptor gamma 2
分子名称: ACETATE ION, CITRIC ACID, Gamma-aminobutyric acid receptor subunit gamma-2, ...
著者Li, J, Ye, J, Zhu, R, Kong, C, Zhang, M, Wang, C.
登録日2020-06-19
公開日2020-12-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Structural basis of GABARAP-mediated GABA A receptor trafficking and functions on GABAergic synaptic transmission.
Nat Commun, 12, 2021
7C6P
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Bromodomain-containing 4 BD2 in complex with 3',4',7,8- Tetrahydroxyflavonoid
分子名称: 2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one, Bromodomain-containing protein 4
著者Li, J, Yu, K, Luo, Y, Zheng, W, Liang, W, Zhu, J.
登録日2020-05-22
公開日2021-05-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor.
J Enzyme Inhib Med Chem, 36, 2021
7C2Z
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Bromodomain-containing 4 BD1 in complex with 3',4',7,8-Tetrahydroxyflavone
分子名称: 2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one, Bromodomain-containing protein 4, FORMIC ACID
著者Li, J, Zhu, J.
登録日2020-05-10
公開日2021-05-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor.
J Enzyme Inhib Med Chem, 36, 2021
7DVM
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DgkA structure in E.coli lipid bilayer
分子名称: Diacylglycerol kinase
著者Li, J, Yang, J.
登録日2021-01-13
公開日2022-04-13
最終更新日2023-09-27
実験手法SOLID-STATE NMR
主引用文献Structure of membrane diacylglycerol kinase in lipid bilayers.
Commun Biol, 4, 2021
5YIS
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BU of 5yis by Molmil
Crystal Structure of AnkB LIR/LC3B complex
分子名称: Ankyrin-2, GLYCEROL, Microtubule-associated proteins 1A/1B light chain 3B, ...
著者Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M.
登録日2017-10-06
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.
Nat. Chem. Biol., 14, 2018
5YIQ
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Crystal structure of AnkG LIR/LC3B complex
分子名称: Ankyrin-3, Microtubule-associated proteins 1A/1B light chain 3B, ZINC ION
著者Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M.
登録日2017-10-06
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.
Nat. Chem. Biol., 14, 2018
5YIR
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Crystal Structure of AnkB LIR/GABARAP complex
分子名称: Ankyrin-2, Gamma-aminobutyric acid receptor-associated protein, NICKEL (II) ION
著者Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M.
登録日2017-10-06
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.
Nat. Chem. Biol., 14, 2018
6JLS
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BU of 6jls by Molmil
Crystal Structure of FMN-dependent Cysteine Decarboxylases TvaF from Thioviridamide Biosynthesis
分子名称: FLAVIN MONONUCLEOTIDE, Putative flavoprotein decarboxylase
著者Li, J, Lu, J, Wang, H, Zhu, J.
登録日2019-03-06
公開日2019-06-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Characterization of the FMN-Dependent Cysteine Decarboxylase from Thioviridamide Biosynthesis.
Org.Lett., 21, 2019
5YIP
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Crystal Structure of AnkG LIR/GABARAPL1 complex
分子名称: Ankyrin-3, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein-like 1
著者Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M.
登録日2017-10-06
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.
Nat. Chem. Biol., 14, 2018
8W6I
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BU of 8w6i by Molmil
Cryo-EM structure of Escherichia coli Str K12 FtsEX complex with ATP-gamma-S in peptidisc
分子名称: Cell division ATP-binding protein FtsE, Cell division protein FtsX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Li, J, Xu, X, He, Y, Luo, M.
登録日2023-08-29
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of Escherichia coli Str K12 FtsEX complex with ATP-gamma-S in peptidisc
To Be Published
8W6J
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Cryo-EM structure of Escherichia coli Str K12 FtsE(E163Q)X/EnvC complex with ATP in peptidisc
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ...
著者Li, J, Xu, X, He, Y, Luo, M.
登録日2023-08-29
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of Escherichia coli Str K12 FtsE(E163Q)X/EnvC complex with ATP in peptidisc
To Be Published
7CUQ
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2.55-Angstrom Cryo-EM structure of Cytochrome bo3 from Escherichia coli in Native Membrane
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ...
著者Li, J, Han, L, Gennis, R.B, Zhu, J.P, Zhang, K.
登録日2020-08-24
公開日2021-08-25
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Cryo-EM structures of Escherichia coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CUW
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Ubiquinol Binding Site of Cytochrome bo3 from Escherichia coli
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ...
著者Li, J, Han, L, Gennis, R.B, Zhu, J.P, Zhang, K.
登録日2020-08-25
公開日2021-08-25
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.63 Å)
主引用文献Cryo-EM structures of Escherichia coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CUB
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2.55-Angstrom Cryo-EM structure of Cytochrome bo3 from Escherichia coli in Native Membrane
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ...
著者Li, J, Han, L, Gennis, R.B, Zhu, J.P, Zhang, K.
登録日2020-08-22
公開日2021-08-25
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Cryo-EM structures of Escherichia coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site.
Proc.Natl.Acad.Sci.USA, 118, 2021
8UOZ
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EmrE structure in the TPP-bound state (WT/E14Q heterodimer)
分子名称: SMR family multidrug efflux protein EmrE, TETRAPHENYLPHOSPHONIUM
著者Li, J, Sae Her, A, Besch, A, Ramirez, B, Crames, M, Banigan, J.R, Mueller, C, Marsiglia, W.M, Zhang, Y, Traaseth, N.J.
登録日2023-10-20
公開日2024-05-29
最終更新日2024-07-03
実験手法SOLID-STATE NMR, SOLUTION NMR
主引用文献Dynamics underlie the drug recognition mechanism by the efflux transporter EmrE.
Nat Commun, 15, 2024
6LDZ
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BU of 6ldz by Molmil
Crystal structure of Rv0222 from Mycobacterium tuberculosis
分子名称: Probable enoyl-CoA hydratase EchA1 (Enoyl hydrase) (Unsaturated acyl-CoA hydratase) (Crotonase)
著者Li, J, Ran, Y.J, Wang, L, Wu, J.H, Ge, B.X, Rao, Z.H.
登録日2019-11-23
公開日2020-01-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Host-mediated ubiquitination of a mycobacterial protein suppresses immunity.
Nature, 577, 2020
8UWU
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EmrE structure in the proton-bound state (WT/L51I heterodimer)
分子名称: SMR family multidrug efflux protein EmrE
著者Li, J, Sae Her, A, Besch, A, Ramirez, B, Crames, M, Banigan, J.R, Mueller, C, Marsiglia, W.M, Zhang, Y, Traaseth, N.J.
登録日2023-11-08
公開日2024-05-29
最終更新日2024-07-03
実験手法SOLID-STATE NMR, SOLUTION NMR
主引用文献Dynamics underlie the drug recognition mechanism by the efflux transporter EmrE.
Nat Commun, 15, 2024

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件を2024-08-07に公開中

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