8UOZ
EmrE structure in the TPP-bound state (WT/E14Q heterodimer)
Summary for 8UOZ
Entry DOI | 10.2210/pdb8uoz/pdb |
NMR Information | BMRB: 31121 |
Descriptor | SMR family multidrug efflux protein EmrE, TETRAPHENYLPHOSPHONIUM (3 entities in total) |
Functional Keywords | multidrug transporter, efflux pump, membrane protein |
Biological source | Escherichia coli More |
Total number of polymer chains | 2 |
Total formula weight | 24264.96 |
Authors | Li, J.,Sae Her, A.,Besch, A.,Ramirez, B.,Crames, M.,Banigan, J.R.,Mueller, C.,Marsiglia, W.M.,Zhang, Y.,Traaseth, N.J. (deposition date: 2023-10-20, release date: 2024-05-29, Last modification date: 2024-07-03) |
Primary citation | Li, J.,Her, A.S.,Besch, A.,Ramirez-Cordero, B.,Crames, M.,Banigan, J.R.,Mueller, C.,Marsiglia, W.M.,Zhang, Y.,Traaseth, N.J. Dynamics underlie the drug recognition mechanism by the efflux transporter EmrE. Nat Commun, 15:4537-4537, 2024 Cited by PubMed: 38806470DOI: 10.1038/s41467-024-48803-2 PDB entries with the same primary citation |
Experimental method | SOLID-STATE NMR SOLUTION NMR |
Structure validation
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