8UOZ
EmrE structure in the TPP-bound state (WT/E14Q heterodimer)
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 17 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000305|PubMed:17005200 |
| Chain | Residue | Details |
| B | TYR4-MET21 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000305|PubMed:17005200 |
| Chain | Residue | Details |
| B | VAL34-ALA52 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000305|PubMed:17005200 |
| Chain | Residue | Details |
| B | ILE58-GLY80 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 17 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000305|PubMed:17005200 |
| Chain | Residue | Details |
| B | ALA87-LEU104 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | SITE: Required for proper coupling between the substrate transport and the proton gradient |
| Chain | Residue | Details |
| B | TYR4 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | SITE: Essential for translocation and for substrate and proton binding => ECO:0000305|PubMed:12590142, ECO:0000305|PubMed:29114048 |
| Chain | Residue | Details |
| B | GLN14 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | SITE: Involved in substrate binding |
| Chain | Residue | Details |
| B | TYR40 | |
| B | TYR60 | |
| B | TRP63 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | SITE: Important for activity => ECO:0000305|PubMed:30287687 |
| Chain | Residue | Details |
| B | HIS110 |
