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PDB: 1767 results

2HAI
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BU of 2hai by Molmil
Crystal structure of HCV NS5B RNA polymerase in complex with novel class of dihydropyrone-containing inhibitor.
Descriptor: (6S)-6-CYCLOPENTYL-6-[2-(3-FLUORO-4-ISOPROPOXYPHENYL)ETHYL]-4-HYDROXY-5,6-DIHYDRO-2H-PYRAN-2-ONE, HEPATITIS C VIRUS NS5B RNA POLYMERASE
Authors:Li, H, Love, R.L.
Deposit date:2006-06-12
Release date:2006-09-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
6BGL
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BU of 6bgl by Molmil
Doubly PafE-capped 20S core particle in Mycobacterium tuberculosis
Descriptor: Bacterial proteasome activator, Proteasome subunit alpha, Proteasome subunit beta
Authors:Li, H, Hu, K.
Deposit date:2017-10-28
Release date:2018-02-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Proteasome substrate capture and gate opening by the accessory factor PafE fromMycobacterium tuberculosis.
J. Biol. Chem., 293, 2018
6BGO
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BU of 6bgo by Molmil
Singly PafE-capped 20S CP in Mycobacterium tuberculosis
Descriptor: Bacterial proteasome activator, Proteasome subunit alpha, Proteasome subunit beta
Authors:Li, H, Hu, K.
Deposit date:2017-10-29
Release date:2018-02-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Proteasome substrate capture and gate opening by the accessory factor PafE fromMycobacterium tuberculosis.
J. Biol. Chem., 293, 2018
2JW2
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BU of 2jw2 by Molmil
Validation of inter-helical orientation of the steril-alpha-motif of human deleted in liver cancer 2 by residual dipolar couplings
Descriptor: StAR-related lipid transfer protein 13
Authors:Li, H, Sze, K, Fung, K.
Deposit date:2007-10-03
Release date:2008-10-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Validation of inter-helical orientation of the steril-alpha-motif of human deleted in liver cancer 2 by residual dipolar couplings
To be Published
7YI2
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BU of 7yi2 by Molmil
Cryo-EM structure of Rpd3S in loose-state Rpd3S-NCP complex
Descriptor: Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ...
Authors:Li, H.T, Yan, C.Y, Guan, H.P, Wang, P.
Deposit date:2022-07-14
Release date:2023-06-14
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023
2AVF
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BU of 2avf by Molmil
Crystal Structure of C-terminal Desundecapeptide Nitrite Reductase from Achromobacter cycloclastes
Descriptor: CHLORIDE ION, COPPER (II) ION, Copper-containing nitrite reductase
Authors:Li, H.T, Chang, T, Chang, W.C, Chen, C.J, Liu, M.Y, Gui, L.L, Zhang, J.P, An, X.M, Chang, W.R.
Deposit date:2005-08-30
Release date:2005-12-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of C-terminal desundecapeptide nitrite reductase from Achromobacter cycloclastes
Biochem.Biophys.Res.Commun., 338, 2005
6BS3
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BU of 6bs3 by Molmil
Crystal structure of ADP-bound bacterial Get3-like A and B in Mycobacterium tuberculosis
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Anion transporter, CALCIUM ION, ...
Authors:Li, H, Hu, K, Kovach, A.
Deposit date:2017-12-01
Release date:2019-05-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Characterization of Guided Entry of Tail-Anchored Proteins 3 Homologues in Mycobacterium tuberculosis.
J.Bacteriol., 201, 2019
3D1D
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BU of 3d1d by Molmil
Hexagonal crystal structure of Tas3 C-terminal alpha motif
Descriptor: RNA-induced transcriptional silencing complex protein tas3
Authors:Li, H, Patel, D.J.
Deposit date:2008-05-05
Release date:2009-04-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
6BS4
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BU of 6bs4 by Molmil
Crystal structure of ATPgammaS-bound bacterial Get3-like A and B in Mycobacterium tuberculosis
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Anion transporter, MAGNESIUM ION, ...
Authors:Li, H, Hu, K, Kovach, A.
Deposit date:2017-12-01
Release date:2019-05-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Characterization of Guided Entry of Tail-Anchored Proteins 3 Homologues in Mycobacterium tuberculosis.
J.Bacteriol., 201, 2019
8HMX
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BU of 8hmx by Molmil
WDR5 in complex with histone H3Q5his peptide
Descriptor: WD repeat-containing protein 5, histone H3Q5his peptide
Authors:Li, H.T, Zhao, S, Wang, H.F.
Deposit date:2022-12-06
Release date:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:WDR5 in complex with histone H3Q5his peptide
To Be Published
1R11
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BU of 1r11 by Molmil
Structure Determination of the Dimeric Endonuclease in a Pseudo-face-centerd P21 space group
Descriptor: tRNA-intron endonuclease
Authors:Li, H, Zhang, Y.
Deposit date:2003-09-23
Release date:2004-03-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure determination of a truncated dimeric splicing endonuclease in pseudo-face-centered space group P2(1)2(1)2.
Acta Crystallogr.,Sect.D, 60, 2004
3E9D
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BU of 3e9d by Molmil
Structure of full-length TIGAR from Danio rerio
Descriptor: PHOSPHATE ION, POTASSIUM ION, Zgc:56074
Authors:Li, H, Jogl, G.
Deposit date:2008-08-21
Release date:2008-12-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:TIGAR (TP53 induced glycolysis and apoptosis regulator) is a fructose-2,6- and fructose-1,6-bisphosphatase
To be Published
1RLV
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BU of 1rlv by Molmil
Crystal structure of a dimeric Archaeal Splicing Endonuclease
Descriptor: Putative tRNA-intron endonuclease
Authors:Li, H, Abelson, J.
Deposit date:2003-11-26
Release date:2003-12-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a dimeric Archaeal Splicing Endonuclease
J.Mol.Biol., 302, 2000
3FD2
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BU of 3fd2 by Molmil
Crystal structure of mMsoI/DNA complex with calcium
Descriptor: 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ...
Authors:Li, H, Monnat, R.J.
Deposit date:2008-11-24
Release date:2009-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins.
Nucleic Acids Res., 37, 2009
3M9B
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BU of 3m9b by Molmil
Crystal structure of the amino terminal coiled coil domain and the inter domain of the Mycobacterium tuberculosis proteasomal ATPase Mpa
Descriptor: Proteasome-associated ATPase
Authors:Li, H, Wang, T.
Deposit date:2010-03-21
Release date:2010-10-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.94 Å)
Cite:Binding-induced folding of prokaryotic ubiquitin-like protein on the Mycobacterium proteasomal ATPase targets substrates for degradation.
Nat.Struct.Mol.Biol., 17, 2010
3M9D
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BU of 3m9d by Molmil
Crystal structure of the prokaryotic ubiquintin-like protein Pup complexed with the hexameric proteasomal ATPase Mpa which includes the amino terminal coiled coil domain and the inter domain
Descriptor: Prokaryotic ubiquitin-like protein pup, Proteasome-associated ATPase
Authors:Li, H, Wang, T.
Deposit date:2010-03-22
Release date:2010-10-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Binding-induced folding of prokaryotic ubiquitin-like protein on the Mycobacterium proteasomal ATPase targets substrates for degradation.
Nat.Struct.Mol.Biol., 17, 2010
2F6N
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BU of 2f6n by Molmil
Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the free form
Descriptor: ZINC ION, bromodomain PHD finger transcription factor
Authors:Li, H, Patel, D.J.
Deposit date:2005-11-29
Release date:2006-07-11
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
2F6J
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BU of 2f6j by Molmil
Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4me3 bound state
Descriptor: ZINC ION, bromodomain PHD finger transcription factor, histone H3, ...
Authors:Li, H, Patel, D.J.
Deposit date:2005-11-29
Release date:2006-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
2FSA
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BU of 2fsa by Molmil
Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4ME2 bound state
Descriptor: Histone H3(1-15)K4me2 peptide, ZINC ION, bromodomain PHD finger transcription factor
Authors:Li, H, Patel, D.J.
Deposit date:2006-01-21
Release date:2006-07-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
3N2R
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BU of 3n2r by Molmil
Structure of neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R/3S,4S)-4-(3-Phenoxyphenoxy)pyrrolidin-3-yl)methyl)pyridin-2-amine
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3R,4R)-4-(3-phenoxyphenoxy)pyrrolidin-3-yl]methyl}pyridin-2-amine, ACETATE ION, ...
Authors:Li, H, Poulos, T.L.
Deposit date:2010-05-18
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-based design, synthesis, and biological evaluation of lipophilic-tailed monocationic inhibitors of neuronal nitric oxide synthase.
Bioorg.Med.Chem., 18, 2010
3NLQ
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BU of 3nlq by Molmil
Structure of neuronal nitric oxide synthase D597N/M336V mutant heme domain in complex with 6-{{(3'R,4'R)-3'-[2"-(3'''-fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
Descriptor: 1,2-ETHANEDIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3R,4R)-4-(2-{[2-(3-fluorophenyl)ethyl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine, ...
Authors:Li, H, Delker, S.L, Poulos, T.L.
Deposit date:2010-06-21
Release date:2010-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives.
J.Med.Chem., 53, 2010
3NLM
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BU of 3nlm by Molmil
Structure of neuronal nitric oxide synthase heme domain in complex with 6-{{(3'R,4'R)-3'-[2"-(3'''-fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3R,4R)-4-(2-{[2-(3-fluorophenyl)ethyl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine, ACETATE ION, ...
Authors:Li, H, Delker, S.L, Poulos, T.L.
Deposit date:2010-06-21
Release date:2010-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives.
J.Med.Chem., 53, 2010
1UEM
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BU of 1uem by Molmil
Solution Structure of the First Fibronectin Type III domain of human KIAA1568 Protein
Descriptor: KIAA1568 Protein
Authors:Li, H, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-19
Release date:2003-11-19
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of the First Fibronectin Type III domain of human KIAA1568 Protein
To be Published
1UEZ
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BU of 1uez by Molmil
Solution structure of the first PDZ domain of human KIAA1526 protein
Descriptor: KIAA1526 Protein
Authors:Li, H, Kigawa, T, Muto, Y, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-22
Release date:2003-11-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the first PDZ domain of human KIAA1526 protein
To be Published
3NLN
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BU of 3nln by Molmil
Structure of neuronal nitric oxide synthase R349A mutant heme domain in complex with 6-{{(3'R,4'S)-3'-[2"-(3'''-fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3S,4R)-4-(2-{[2-(3-fluorophenyl)ethyl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine, ACETATE ION, ...
Authors:Li, H, Delker, S.L, Poulos, T.L.
Deposit date:2010-06-21
Release date:2010-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives.
J.Med.Chem., 53, 2010

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數據於2024-05-29公開中

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