8G6E
 
 | | Structure of the Plasmodium falciparum 20S proteasome complexed with inhibitor TDI-8304 | | Descriptor: | (7S,10S,13S)-N-cyclopentyl-10-[2-(morpholin-4-yl)ethyl]-9,12-dioxo-13-(2-oxopyrrolidin-1-yl)-2-oxa-8,11-diazabicyclo[13.3.1]nonadeca-1(19),15,17-triene-7-carboxamide, Proteasome subunit alpha type, Proteasome subunit alpha type-1, ... | | Authors: | Hsu, H.-C, Li, H. | | Deposit date: | 2023-02-15 | | Release date: | 2023-12-20 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (2.18 Å) | | Cite: | Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors.
Nat Commun, 14, 2023
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1GIK
 | | POKEWEED ANTIVIRAL PROTEIN FROM SEEDS | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIVIRAL PROTEIN S | | Authors: | Zeng, Z.H, He, X.L, Li, H.M, Hu, Z, Wang, D.C. | | Deposit date: | 2001-02-07 | | Release date: | 2003-09-30 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of pokeweed antiviral protein with well-defined sugars from seeds at 1.8 angstrom resolution
J.Struct.Biol., 141, 2003
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1P6L
 | | Bovine endothelial NOS heme domain with L-N(omega)-nitroarginine-2,4-L-diaminobutyric amide bound | | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ... | | Authors: | Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.-M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L. | | Deposit date: | 2003-04-29 | | Release date: | 2004-01-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
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6KDS
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6L94
 | | The structure of the dioxygenase ABH1 from mouse | | Descriptor: | FE (II) ION, Nucleic acid dioxygenase ALKBH1 | | Authors: | Xie, W, Wang, C, Li, H, Zhang, Y. | | Deposit date: | 2019-11-08 | | Release date: | 2020-11-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.10012341 Å) | | Cite: | ALKBH1 promotes lung cancer by regulating m6A RNA demethylation.
Biochem Pharmacol, 189, 2021
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8UD9
 | | Structure of human constitutive 20S proteasome complexed with the inhibitor TDI-8304 | | Descriptor: | (7S,10S,13S)-N-cyclopentyl-10-[2-(morpholin-4-yl)ethyl]-9,12-dioxo-13-(2-oxopyrrolidin-1-yl)-2-oxa-8,11-diazabicyclo[13.3.1]nonadeca-1(19),15,17-triene-7-carboxamide, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | | Authors: | Hsu, H.-C, Li, H. | | Deposit date: | 2023-09-28 | | Release date: | 2023-12-20 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (2.04 Å) | | Cite: | Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors.
Nat Commun, 14, 2023
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1BVY
 | | COMPLEX OF THE HEME AND FMN-BINDING DOMAINS OF THE CYTOCHROME P450(BM-3) | | Descriptor: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, PROTEIN (CYTOCHROME P450 BM-3), ... | | Authors: | Sevrioukova, I.F, Li, H, Zhang, H, Peterson, J.A, Poulos, T.L. | | Deposit date: | 1998-09-21 | | Release date: | 1999-02-23 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structure of a cytochrome P450-redox partner electron-transfer complex.
Proc.Natl.Acad.Sci.USA, 96, 1999
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8D6Y
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8D6W
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8D6V
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8D6X
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5GJA
 | | Crystal structure of Arabidopsis thaliana ACO2 in complex with 2-PA | | Descriptor: | 1-aminocyclopropane-1-carboxylate oxidase 2, PYRIDINE-2-CARBOXYLIC ACID, ZINC ION | | Authors: | Sun, X.Z, Li, Y.X, He, W.R, Ji, C.G, Xia, P.X, Wang, Y.C, Du, S, Li, H.J, Raikhel, N, Xiao, J.Y, Guo, H.W. | | Deposit date: | 2016-06-28 | | Release date: | 2017-05-10 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Pyrazinamide and derivatives block ethylene biosynthesis by inhibiting ACC oxidase.
Nat Commun, 8, 2017
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4WMA
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4WN2
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6XN5
 | | Structure of the Lactococcus lactis Csm Apo- CRISPR-Cas Complex | | Descriptor: | CRISPR-associated protein Cas10, CRISPR-associated protein Csm3, CRISPR-associated protein Csm4, ... | | Authors: | Rai, J, Sridhara, S, Li, H. | | Deposit date: | 2020-07-02 | | Release date: | 2022-01-12 | | Last modified: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (2.97 Å) | | Cite: | Structural and biochemical characterization of in vivo assembled Lactococcus lactis CRISPR-Csm complex.
Commun Biol, 5, 2022
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6XN4
 | | Structure of the Lactococcus lactis Csm CTR_3:2 CRISPR-Cas Complex | | Descriptor: | CRISPR-associated protein Cas10, CRISPR-associated protein Csm2, CRISPR-associated protein Csm3, ... | | Authors: | Rai, J, Sridhara, S, Li, H. | | Deposit date: | 2020-07-02 | | Release date: | 2022-01-12 | | Last modified: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structural and biochemical characterization of in vivo assembled Lactococcus lactis CRISPR-Csm complex.
Commun Biol, 5, 2022
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6XN3
 | | Structure of the Lactococcus lactis Csm CTR_4:3 CRISPR-Cas Complex | | Descriptor: | CRISPR-associated protein Cas10, CRISPR-associated protein Csm2, CRISPR-associated protein Csm3, ... | | Authors: | Rai, J, Sridhara, S, Li, H. | | Deposit date: | 2020-07-02 | | Release date: | 2022-01-12 | | Last modified: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural and biochemical characterization of in vivo assembled Lactococcus lactis CRISPR-Csm complex.
Commun Biol, 5, 2022
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6XN7
 | | Structure of the Lactococcus lactis Csm NTR CRISPR-Cas Complex | | Descriptor: | CRISPR-associated protein Cas10, CRISPR-associated protein Csm2, CRISPR-associated protein Csm3, ... | | Authors: | Rai, J, Sridhara, S, Li, H. | | Deposit date: | 2020-07-02 | | Release date: | 2022-01-12 | | Last modified: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Structural and biochemical characterization of in vivo assembled Lactococcus lactis CRISPR-Csm complex.
Commun Biol, 5, 2022
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4WMI
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4WLM
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4WMB
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4WMK
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7SUK
 | | Structure of Bfr2-Lcp5 Complex Observed in the Small Subunit Processome Isolated from R2TP-depleted Yeast Cells | | Descriptor: | 18S pre-rRNA, 40S ribosomal protein S11-A, 40S ribosomal protein S13, ... | | Authors: | Rai, J, Zhao, Y, Li, H. | | Deposit date: | 2021-11-17 | | Release date: | 2022-07-06 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (3.99 Å) | | Cite: | Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome.
Commun Biol, 5, 2022
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5TJA
 | | I-II linker of TRPML1 channel at pH 6 | | Descriptor: | Mucolipin-1 | | Authors: | Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J. | | Deposit date: | 2016-10-04 | | Release date: | 2017-01-25 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel.
Nat. Struct. Mol. Biol., 24, 2017
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5TJC
 | | I-II linker of TRPML1 channel at pH 7.5 | | Descriptor: | Mucolipin-1 | | Authors: | Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J. | | Deposit date: | 2016-10-04 | | Release date: | 2017-01-25 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel.
Nat. Struct. Mol. Biol., 24, 2017
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