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PDB: 1804 件

8SXH
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Structure of the C-terminal protease CtpA-LbcA complex of Pseudomonas aeruginosa
分子名称: Carboxyl-terminal protease, TPR repeat-containing protein PA4667, unidentified peptide
著者Hsu, H.-C, Li, H.
登録日2023-05-22
公開日2024-03-06
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.94 Å)
主引用文献P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process.
Embo J., 43, 2024
6VSI
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BU of 6vsi by Molmil
Crystal structure of FKBP12 of Candida auris
分子名称: Peptidylprolyl isomerase, SULFATE ION
著者Li, Z, Li, H, Hernandez, G, LeMaster, D.
登録日2020-02-11
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structure and transient dimerization for the FKBP12 protein from the pathogenic fungus Candida auris.
Biochem.Biophys.Res.Commun., 525, 2020
1I83
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BU of 1i83 by Molmil
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH N1,N14-BIS((S-METHYL)ISOTHIOUREIDO)TETRADECANE (H4B FREE)
分子名称: ACETATE ION, GLYCEROL, N1,N14-BIS((S-METHYL)ISOTHIOUREIDO)TETRADECANE, ...
著者Raman, C.S, Li, H, Martasek, P, Babu, B.R, Griffith, O.W, Masters, B.S.S, Poulos, T.L.
登録日2001-03-12
公開日2001-08-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase.
J.Biol.Chem., 276, 2001
3HF9
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BU of 3hf9 by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant modified by inhibitor GL1
分子名称: Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB
著者Li, D, Li, H.
登録日2009-05-11
公開日2009-09-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.878 Å)
主引用文献Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
2A3R
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Crystal Structure of Human Sulfotransferase SULT1A3 in Complex with Dopamine and 3-Phosphoadenosine 5-Phosphate
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, L-DOPAMINE, Monoamine-sulfating phenol sulfotransferase
著者Lu, J.H, Li, H.T, Liu, M.C, Zhang, J.P, Li, M, An, X.M, Chang, W.R.
登録日2005-06-26
公開日2005-08-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of human sulfotransferase SULT1A3 in complex with dopamine and 3'-phosphoadenosine 5'-phosphate
Biochem.Biophys.Res.Commun., 335, 2005
1P6I
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BU of 1p6i by Molmil
Rat neuronal NOS heme domain with (4S)-N-(4-amino-5-[aminoethyl]aminopentyl)-N'-nitroguanidine bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{(4S)-4-AMINO-5-[(2-AMINOETHYL)AMINO]PENTYL}-N'-NITROGUANIDINE, ...
著者Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.-M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6J
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Rat neuronal NOS heme domain with L-N(omega)-nitroarginine-(4R)-amino-L-proline amide bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE, ...
著者Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.-M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
6LR6
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BU of 6lr6 by Molmil
The crystal structure of human cytoplasmic LRS
分子名称: 4-Chloro-3-aminomethyl-7-[ethoxy]-3H-benzo[C][1,2]oxaborol-1-ol modified adenosine, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ...
著者Liu, R.J, Long, T, Li, H, Li, J, Zhao, J.H, Lin, J.Z, Palencia, A, Wang, M.Z, Cusack, S, Wang, E.D.
登録日2020-01-15
公開日2020-03-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.009 Å)
主引用文献Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond.
Nucleic Acids Res., 48, 2020
1P6M
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Bovine endothelial NOS heme domain with (4S)-N-(4-amino-5-[aminoethyl]aminopentyl)-N'-nitroguanidine bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ...
著者Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.-M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
5TJA
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BU of 5tja by Molmil
I-II linker of TRPML1 channel at pH 6
分子名称: Mucolipin-1
著者Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J.
登録日2016-10-04
公開日2017-01-25
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel.
Nat. Struct. Mol. Biol., 24, 2017
5TJC
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I-II linker of TRPML1 channel at pH 7.5
分子名称: Mucolipin-1
著者Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J.
登録日2016-10-04
公開日2017-01-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel.
Nat. Struct. Mol. Biol., 24, 2017
7WYF
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BU of 7wyf by Molmil
Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) in complex with its inhibitor 50
分子名称: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
著者Zhu, L, Li, H.
登録日2022-02-16
公開日2023-02-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) in complex with its inhibitor 50
To Be Published
6MWY
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BU of 6mwy by Molmil
The Prp8 intein of Cryptococcus gattii
分子名称: Pre-mRNA-processing-splicing factor 8
著者Li, Z, Fu, B, Green, C.M, Lang, Y, Zhang, J, Oven, T.S, Li, X, Callahan, B.P, Chaturvedi, S, Belfort, M, Liao, G, Li, H.
登録日2018-10-30
公開日2019-11-06
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Cisplatin protects mice from challenge ofCryptococcus neoformansby targeting the Prp8 intein.
Emerg Microbes Infect, 8, 2019
6MYL
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The Prp8 intein-cisplatin complex
分子名称: PLATINUM (II) ION, Pre-mRNA-processing-splicing factor 8
著者Li, Z, Li, H.
登録日2018-11-01
公開日2019-11-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Cisplatin protects mice from challenge ofCryptococcus neoformansby targeting the Prp8 intein.
Emerg Microbes Infect, 8, 2019
6MX6
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BU of 6mx6 by Molmil
The Prp8 intein of Cryptococcus neoformans
分子名称: Pre-mRNA-processing-splicing factor 8
著者Li, Z, Li, H.
登録日2018-10-30
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing.
Plos Biol., 17, 2019
8SXG
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BU of 8sxg by Molmil
The C-terminal protease CtpA-LbcA complex of pseudomonas aeruginosa with the TPR at the low position
分子名称: Probable carboxyl-terminal protease, TPR repeat-containing protein PA4667, unidentified peptide
著者Hsu, H.-C, Li, H.
登録日2023-05-22
公開日2024-03-06
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process.
Embo J., 43, 2024
8SXE
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BU of 8sxe by Molmil
Structure of the C-terminal protease CtpA-LbcA complex of Pseudomonas aeruginosa
分子名称: Probable carboxyl-terminal protease, TPR repeat-containing protein PA4667, unidentified peptide
著者Hsu, H.-C, Li, H.
登録日2023-05-22
公開日2024-03-06
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process.
Embo J., 43, 2024
8SXF
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BU of 8sxf by Molmil
The C-terminal protease CtpA-LbcA complex of pseudomonas aeruginosa with the TPR at the high position
分子名称: Probable carboxyl-terminal protease, TPR repeat-containing protein PA4667, polyA
著者Hsu, H.-C, Li, H.
登録日2023-05-22
公開日2024-03-06
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process.
Embo J., 43, 2024
7NSE
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BU of 7nse by Molmil
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE, H4B-FREE, ADMA COMPLEX
分子名称: ACETATE ION, CACODYLIC ACID, GLYCEROL, ...
著者Raman, C.S, Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L.
登録日1999-01-13
公開日2002-05-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structures of the Heme Domain of Bovine Endothelial Nitric Oxide Synthase Complexed with Arginine Analogues
To be Published
1P6K
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BU of 1p6k by Molmil
Rat neuronal NOS D597N mutant heme domain with L-N(omega)-nitroarginine-2,4-L-diaminobutyric amide bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, D-MANNITOL, ...
著者Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.-M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6N
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BU of 1p6n by Molmil
Bovine endothelial NOS heme domain with L-N(omega)-nitroarginine-(4R)-amino-L-proline amide bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ...
著者Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.-M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
5TJB
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BU of 5tjb by Molmil
I-II linker of TRPML1 channel at pH 4.5
分子名称: Mucolipin-1
著者Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J.
登録日2016-10-04
公開日2017-01-25
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel.
Nat. Struct. Mol. Biol., 24, 2017
7T30
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BU of 7t30 by Molmil
Structure of electron bifurcating Ni-Fe hydrogenase complex HydABCSL in FMN/NAD(H) bound state
分子名称: CARBONMONOXIDE-(DICYANO) IRON, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
著者Feng, X, Li, H.
登録日2021-12-06
公開日2022-03-16
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase.
Sci Adv, 8, 2022
7T2R
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BU of 7t2r by Molmil
Structure of electron bifurcating Ni-Fe hydrogenase complex HydABCSL in FMN-free apo state
分子名称: CARBONMONOXIDE-(DICYANO) IRON, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, ...
著者Feng, X, Li, H.
登録日2021-12-06
公開日2022-03-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase.
Sci Adv, 8, 2022
5VIE
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BU of 5vie by Molmil
Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase
分子名称: 2-{[(2E)-4-chlorobut-2-enoyl]amino}-2-deoxy-beta-D-glucopyranose, 2-{[(2E)-but-2-enoyl]amino}-2-deoxy-beta-D-glucopyranose, CKII, ...
著者Jiang, J, Li, B, Hu, C.-W, Worth, M, Fan, D, Li, H.
登録日2017-04-15
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase.
Nat. Chem. Biol., 13, 2017

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