4UC3
 
 | | Translocator protein 18 kDa (TSPO) from Rhodobacter sphaeroides wild type | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, TRANSLOCATOR PROTEIN TSPO | | Authors: | Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S. | | Deposit date: | 2014-08-13 | | Release date: | 2015-02-04 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
Science, 347, 2015
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6MDX
 | | Mechanism of protease dependent DPC repair | | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, DNA (5'-D(P*CP*C)-3'), ... | | Authors: | Li, F, Raczynska, J, Chen, Z, Yu, H. | | Deposit date: | 2018-09-05 | | Release date: | 2019-04-10 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan.
Cell Rep, 26, 2019
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6OCG
 | | Crystal structure of VASH1-SVBP complex bound with EpoY | | Descriptor: | CHLORIDE ION, GLYCEROL, N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-tyrosine, ... | | Authors: | Li, F, Luo, X, Yu, H. | | Deposit date: | 2019-03-23 | | Release date: | 2019-06-26 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.833 Å) | | Cite: | Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019
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6OCF
 | | The crystal structure of VASH1-SVBP complex | | Descriptor: | CHLORIDE ION, GLYCEROL, Small vasohibin-binding protein, ... | | Authors: | Li, F, Luo, X, Yu, H. | | Deposit date: | 2019-03-23 | | Release date: | 2019-06-26 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (2.102 Å) | | Cite: | Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019
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7SFS
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7SG7
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7SP4
 | | In situ cryo-EM structure of bacteriophage Sf6 gp3:gp7:gp5 complex in conformation 2 at 3.71A resolution | | Descriptor: | Gene 3 protein, Gene 5 protein, Gene 7 protein | | Authors: | Li, F, Cingolani, G, Hou, C, Yang, R. | | Deposit date: | 2021-11-02 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.71 Å) | | Cite: | High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine.
Sci Adv, 8, 2022
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7SPU
 | | In situ cryo-EM structure of bacteriophage Sf6 gp3:gp7:gp5 complex in conformation 1 at 3.73A resolution | | Descriptor: | Gene 3 protein, Gene 5 protein, Gene 7 protein | | Authors: | Li, F, Cingolani, G, Hou, C, Yang, R. | | Deposit date: | 2021-11-03 | | Release date: | 2022-11-23 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine.
Sci Adv, 8, 2022
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7T3N
 | | R184Q/E191Q mutant of rat vesicular glutamate transporter 2 (VGLUT2) | | Descriptor: | (1S,3R)-1-AMINOCYCLOPENTANE-1,3-DICARBOXYLIC ACID, (2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Vesicular glutamate transporter 2 | | Authors: | Li, F, Stroud, R.M, Edwards, R.H. | | Deposit date: | 2021-12-08 | | Release date: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Substrate Recognition, Directional Flux, and Allostery in a Synaptic Vesicle Glutamate Transporter
To Be Published
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7T3O
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8SBE
 | | Structure of the rat vesicular glutamate transporter 2 determined by single-particle Cryo-EM | | Descriptor: | Vesicular glutamate transporter 2 | | Authors: | Li, F, Finer-Moore, J, Eriksen, J, Cheng, Y, Edwards, R, Stroud, R. | | Deposit date: | 2023-04-03 | | Release date: | 2023-05-03 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Ion transport and regulation in a synaptic vesicle glutamate transporter.
Science, 368, 2020
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4XYW
 | | Glycosyltransferases WbnH | | Descriptor: | O-antigen biosynthesis glycosyltransferase WbnH, SULFATE ION | | Authors: | Li, F. | | Deposit date: | 2015-02-03 | | Release date: | 2016-02-10 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Glycosyltransferases WbnH
To Be Published
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4Y3I
 | | PAS-GAF fragment from Deinococcus radiodurans BphP assembled with BV - Y307S, low dose | | Descriptor: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | | Authors: | Li, F, Burgie, E.S, Yu, T, Heroux, A, Schatz, G.C, Vierstra, R.D, Orville, A.M. | | Deposit date: | 2015-02-10 | | Release date: | 2015-05-20 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | X-ray radiation induces deprotonation of the bilin chromophore in crystalline D. radiodurans phytochrome.
J.Am.Chem.Soc., 137, 2015
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4Y5F
 | | PAS-GAF fragment from Deinococcus radiodurans BphP assembled with BV - Y307S, high dose | | Descriptor: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | | Authors: | Li, F, Burgie, E.S, Yu, T, Heroux, A, Schatz, G.C, Vierstra, R.D, Orville, A.M. | | Deposit date: | 2015-02-11 | | Release date: | 2015-05-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | X-ray radiation induces deprotonation of the bilin chromophore in crystalline D. radiodurans phytochrome.
J.Am.Chem.Soc., 137, 2015
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1MIV
 | | Crystal structure of Bacillus stearothermophilus CCA-adding enzyme | | Descriptor: | MAGNESIUM ION, tRNA CCA-adding enzyme | | Authors: | Li, F, Xiong, Y, Wang, J, Cho, H.D, Weiner, A.M, Steitz, T.A. | | Deposit date: | 2002-08-23 | | Release date: | 2002-12-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and
its complexes with ATP or CTP
Cell(Cambridge,Mass.), 111, 2002
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1MIW
 | | Crystal structure of Bacillus stearothermophilus CCA-adding enzyme in complex with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tRNA CCA-adding enzyme | | Authors: | Li, F, Xiong, Y, Wang, J, Cho, H.D, Weiner, A.M, Steitz, T.A. | | Deposit date: | 2002-08-23 | | Release date: | 2002-12-13 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and
its complexes with ATP or CTP
Cell(Cambridge,Mass.), 111, 2002
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1MIY
 | | Crystal structure of Bacillus stearothermophilus CCA-adding enzyme in complex with CTP | | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tRNA CCA-adding enzyme | | Authors: | Li, F, Xiong, Y, Wang, J, Cho, H.D, Weiner, A.M, Steitz, T.A. | | Deposit date: | 2002-08-23 | | Release date: | 2002-12-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.52 Å) | | Cite: | Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and
its complexes with ATP or CTP
Cell(Cambridge,Mass.), 111, 2002
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3D0H
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3D0I
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5DUO
 | | Crystal structure of native translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FORMIC ACID, PROTOPORPHYRIN IX, ... | | Authors: | Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S. | | Deposit date: | 2015-09-20 | | Release date: | 2015-11-11 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Response to Comment on "Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism".
Science, 350, 2015
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5EOA
 | | Crystal structure of OPTN E50K mutant and TBK1 complex | | Descriptor: | Optineurin, Serine/threonine-protein kinase TBK1 | | Authors: | Li, F, Xie, X, Liu, J, Pan, L. | | Deposit date: | 2015-11-10 | | Release date: | 2016-09-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.503 Å) | | Cite: | Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
Nat Commun, 7, 2016
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3D0G
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5EOF
 | | Crystal structure of OPTN NTD and TBK1 CTD complex | | Descriptor: | Optineurin, Serine/threonine-protein kinase TBK1 | | Authors: | Li, F, Xie, X, Liu, J, Pan, L. | | Deposit date: | 2015-11-10 | | Release date: | 2016-09-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
Nat Commun, 7, 2016
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5EP6
 | | The crystal structure of NAP1 in complex with TBK1 | | Descriptor: | 5-azacytidine-induced protein 2, GLYCEROL, Serine/threonine-protein kinase TBK1 | | Authors: | Li, F, Xie, X, Liu, J, Pan, L. | | Deposit date: | 2015-11-11 | | Release date: | 2016-09-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.451 Å) | | Cite: | Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
Nat Commun, 7, 2016
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8VKJ
 | | Cryo-EM structure of human HGSNAT bound with Acetyl-CoA | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYL COENZYME *A, ... | | Authors: | Li, F, Zhao, B. | | Deposit date: | 2024-01-09 | | Release date: | 2024-06-26 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome.
Nat Commun, 15, 2024
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