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PDB: 51 件
3D3V
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The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(3,4-difluoroPhenylalanine)) peptide
分子名称: A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ...
著者Borbulevych, O.Y, Clemens, J.R, Baker, B.M.
登録日2008-05-12
公開日2009-06-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner.
Biochem.J., 423, 2009
1N8Q
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LIPOXYGENASE IN COMPLEX WITH PROTOCATECHUIC ACID
分子名称: 3,4-DIHYDROXYBENZOIC ACID, FE (II) ION, lipoxygenase-3
著者Borbulevych, O.Y, Jankun, J, Selman, S.H, Skrzypczak-Jankun, E.
登録日2002-11-21
公開日2003-06-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Lipoxygenase interactions with natural flavonoid, quercetin, reveal a complex with protocatechuic acid in its X-ray structure at 2.1 A resolution.
PROTEINS: STRUCT.,FUNCT.,GENET., 54, 2004
1RRH
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Soybean Lipoxygenase (LOX-3) at ambient temperatures at 2.0 A resolution
分子名称: FE (II) ION, Seed lipoxygenase-3
著者Borbulevych, O.Y, Jankun, J, Skrzypczak-Jankun, E.
登録日2003-12-08
公開日2004-12-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Effect of crystal freezing and small-molecule binding on internal cavity size in a large protein: X-ray and docking studies of lipoxygenase at ambient and low temperature at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 62, 2006
2AV7
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BU of 2av7 by Molmil
Crystal structure of HTLV-1 TAX peptide Bound to Human Class I MHC HLA-A2 with the K66A mutation in the heavy chain.
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2005-08-29
公開日2005-10-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants.
J.Mol.Biol., 353, 2005
2AV1
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BU of 2av1 by Molmil
Crystal structure of HTLV-1 TAX peptide Bound to Human Class I MHC HLA-A2 with the E63Q and K66A mutations in the heavy chain.
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2005-08-29
公開日2005-10-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants.
J.Mol.Biol., 353, 2005
1RRL
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Soybean Lipoxygenase (LOX-3) at 93K at 2.0 A resolution
分子名称: FE (II) ION, Seed lipoxygenase-3
著者Borbulevych, O.Y, Jankun, J, Skrzypczak-Jankun, E.
登録日2003-12-08
公開日2004-12-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Effect of crystal freezing and small-molecule binding on internal cavity size in a large protein: X-ray and docking studies of lipoxygenase at ambient and low temperature at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 62, 2006
1TVB
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Crystal structure of Melanoma Antigen gp100(209-217) Bound to Human Class I MHC HLA-A2
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2004-06-29
公開日2005-04-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
J.Immunol., 174, 2005
1TVH
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Crystal structure of Modified Melanoma Antigen gp100(209-T2M) Bound to Human Class I MHC HLA-A2
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2004-06-29
公開日2005-04-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
J.Immunol., 174, 2005
3O3D
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Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-2
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-07-23
公開日2010-12-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010
3O3A
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Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-1
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-07-23
公開日2010-12-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010
3O3E
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Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-2.1
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-07-23
公開日2010-12-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010
3O3B
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BU of 3o3b by Molmil
Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-1.1
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-07-23
公開日2010-12-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010
2GTZ
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BU of 2gtz by Molmil
Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A28L substitution
分子名称: Beta-2-microglobulin, GLYCEROL, HLA-A*0201 heavy chain, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2006-04-28
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
2GUO
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BU of 2guo by Molmil
Human Class I MHC HLA-A2 in complex with the native nonameric Melan-A/MART-1(27-35) peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2006-05-01
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
2GT9
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BU of 2gt9 by Molmil
Human Class I MHC HLA-A2 in complex with the decameric Melan-A/MART-1(26-35) peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2006-04-27
公開日2007-06-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
2GTW
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BU of 2gtw by Molmil
Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A27L substitution
分子名称: Beta-2-microglobulin, FORMIC ACID, GLYCEROL, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2006-04-28
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.548 Å)
主引用文献Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
2GIT
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BU of 2git by Molmil
Human Class I MHC HLA-A2 in complex with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide
分子名称: Beta-2-microglobulin, FORMIC ACID, GLYCEROL, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2006-03-29
公開日2006-10-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献T Cell Receptor Recognition via Cooperative Conformational Plasticity.
J.Mol.Biol., 363, 2006
4FTV
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BU of 4ftv by Molmil
The complex between the high affinity version of A6 TCR (A6c134) and human Class I MHC HLA-A2 with the bound TAX nonameric peptide
分子名称: A6 alpha chain, A6 beta chain, Beta-2-microglobulin, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2012-06-28
公開日2013-07-03
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Structure of a high affinity TCR reveals native binding to MHC with enhanced peptide specificity
To be Published
2GJ6
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The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide
分子名称: 3-INDOLEBUTYRIC ACID, A6-Tcr, Beta-2-microglobulin, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2006-03-30
公開日2006-10-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献T Cell Receptor Recognition via Cooperative Conformational Plasticity.
J.Mol.Biol., 363, 2006
3PWJ
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BU of 3pwj by Molmil
Human Class I MHC HLA-A2 in complex with the HuD (G2L,I9V) peptide variant
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-12-08
公開日2011-03-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
3PWL
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BU of 3pwl by Molmil
Human Class I MHC HLA-A2 in complex with the HuD peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2010-12-08
公開日2011-03-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
3HPJ
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Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-06-04
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A*0201: Implications for WT1-based cancer therapeutics.
Mol.Immunol., 47, 2010
3IXA
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Human Class I MHC HLA-A2(A150P) in complex with the Tax peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-09-03
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3H7B
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Human Class I MHC HLA-A2 in complex with the Tel1p peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-04-24
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3H9H
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Human Class I MHC HLA-A2(A150P) in complex with the Tel1p peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-04-30
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009

 

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