3F6E
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![BU of 3f6e by Molmil](/molmil-images/mine/3f6e) | Crystal structure of benzoylformate decarboxylase in complex with the pyridyl inhibitor 3-PKB | Descriptor: | 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-2-[(1S,2E)-1-hydroxy-3-pyridin-3-ylprop-2-en-1-yl]-4-methyl-1,3-thiazol-3-ium, Benzoylformate decarboxylase, MAGNESIUM ION | Authors: | Brandt, G.S, McLeish, M.J, Kenyon, G.L, Petsko, G.A, Ringe, D, Jordan, F. | Deposit date: | 2008-11-05 | Release date: | 2008-12-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase. Biochemistry, 48, 2009
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2VZ9
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2VZ8
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6ZOK
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![BU of 6zok by Molmil](/molmil-images/mine/6zok) | SARS-CoV-2-Nsp1-40S complex, focused on body | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | Authors: | Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M, Thiel, V, Muehlemann, O, Ban, N. | Deposit date: | 2020-07-07 | Release date: | 2020-07-29 | Last modified: | 2021-02-10 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
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3F6B
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![BU of 3f6b by Molmil](/molmil-images/mine/3f6b) | Crystal structure of benzoylformate decarboxylase in complex with the pyridyl inhibitor PAA | Descriptor: | 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-2-[(1S,2E)-1-hydroxy-3-pyridin-3-ylprop-2-en-1-yl]-4-methyl-1,3-thiazol-3-ium, Benzoylformate decarboxylase, MAGNESIUM ION | Authors: | Brandt, G.S, McLeish, M.J, Kenyon, G.L, Petsko, G.A, Ringe, D, Jordan, F. | Deposit date: | 2008-11-05 | Release date: | 2008-12-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase. Biochemistry, 48, 2009
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1E5J
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![BU of 1e5j by Molmil](/molmil-images/mine/1e5j) | ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS IN THE TETRAGONAL CRYSTAL FORM IN COMPLEX WITH METHYL-4II-S-ALPHA-CELLOBIOSYL-4II-THIO-BETA-CELLOBIOSIDE | Descriptor: | CALCIUM ION, ENDOGLUCANASE 5A, alpha-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-methyl beta-D-glucopyranoside | Authors: | Fort, S, Varrot, A, Schulein, M, Cottaz, S, Driguez, H, Davies, G.J. | Deposit date: | 2000-07-26 | Release date: | 2001-07-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Mixed-Linkage Cellooligosaccharides: A New Class of Glycoside Hydrolase Inhibitors Chembiochem, 2, 2001
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2AN5
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![BU of 2an5 by Molmil](/molmil-images/mine/2an5) | Structure of human PNMT complexed with S-adenosyl-homocysteine and an inhibitor, trans-(1S,2S)-2-amino-1-tetralol | Descriptor: | PHOSPHATE ION, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Gee, C.L, Tyndall, J.D.A, Grunewald, G.L, Wu, Q, McLeish, M.J, Martin, J.L. | Deposit date: | 2005-08-11 | Release date: | 2006-03-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis Biochemistry, 44, 2005
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3FSJ
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![BU of 3fsj by Molmil](/molmil-images/mine/3fsj) | Crystal structure of benzoylformate decarboxylase in complex with the inhibitor MBP | Descriptor: | 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, Benzoylformate decarboxylase, CALCIUM ION | Authors: | Brandt, G.S, Kenyon, G.L, McLeish, M.J, Jordan, F, Petsko, G.A, Ringe, D. | Deposit date: | 2009-01-09 | Release date: | 2009-01-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Snapshot of a reaction intermediate: analysis of benzoylformate decarboxylase in complex with a benzoylphosphonate inhibitor. Biochemistry, 48, 2009
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2AN3
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![BU of 2an3 by Molmil](/molmil-images/mine/2an3) | Structure of PNMT with S-adenosyl-L-homocysteine and the semi-rigid analogue acceptor substrate cis-(1R,2S)-2-amino-1-tetralol. | Descriptor: | CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Gee, C.L, Tyndall, J.D.A, Grunewald, G.L, Wu, Q, McLeish, M.J, Martin, J.L. | Deposit date: | 2005-08-11 | Release date: | 2006-03-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis Biochemistry, 44, 2005
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2AN4
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![BU of 2an4 by Molmil](/molmil-images/mine/2an4) | Structure of PNMT complexed with S-adenosyl-L-homocysteine and the acceptor substrate octopamine | Descriptor: | 4-(2R-AMINO-1-HYDROXYETHYL)PHENOL, PHOSPHATE ION, Phenylethanolamine N-methyltransferase, ... | Authors: | Gee, C.L, Tyndall, J.D.A, Grunewald, G.L, Wu, Q, McLeish, M.J, Martin, J.L. | Deposit date: | 2005-08-11 | Release date: | 2006-03-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis Biochemistry, 44, 2005
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1DJF
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![BU of 1djf by Molmil](/molmil-images/mine/1djf) | NMR STRUCTURE OF A MODEL HYDROPHILIC AMPHIPATHIC HELICAL BASIC PEPTIDE | Descriptor: | GLN-ALA-PRO-ALA-TYR-LYS-LYS-ALA-ALA-LYS-LYS-LEU-ALA-GLU-SER | Authors: | Montserret, R, McLeish, M.J, Bockmann, A, Geourjon, C, Penin, F. | Deposit date: | 1999-12-03 | Release date: | 1999-12-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Involvement of electrostatic interactions in the mechanism of peptide folding induced by sodium dodecyl sulfate binding. Biochemistry, 39, 2000
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1DNG
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![BU of 1dng by Molmil](/molmil-images/mine/1dng) | NMR STRUCTURE OF A MODEL HYDROPHILIC AMPHIPATHIC HELICAL ACIDIC PEPTIDE | Descriptor: | HUMAN PLATELET FACTOR 4, SEGMENT 59-73 | Authors: | montserret, R, McLeish, M.J, Bockmann, A, Geourjon, C, Penin, F. | Deposit date: | 1999-12-16 | Release date: | 2000-01-12 | Last modified: | 2024-04-10 | Method: | SOLUTION NMR | Cite: | Involvement of electrostatic interactions in the mechanism of peptide folding induced by sodium dodecyl sulfate binding. Biochemistry, 39, 2000
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2JSB
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![BU of 2jsb by Molmil](/molmil-images/mine/2jsb) | Solution structure of arenicin-1 | Descriptor: | Arenicin-1 | Authors: | Jakovkin, I.B, Hecht, O, Gelhaus, C, Krasnosdembskaya, A.D, Fedders, H, Leippe, M, Groetzinger, J. | Deposit date: | 2007-07-02 | Release date: | 2008-02-05 | Last modified: | 2020-02-19 | Method: | SOLUTION NMR | Cite: | Structure and mode of action of the antimicrobial peptide arenicin Biochem.J., 410, 2008
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2JRZ
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![BU of 2jrz by Molmil](/molmil-images/mine/2jrz) | Solution structure of the Bright/ARID domain from the human JARID1C protein. | Descriptor: | Histone demethylase JARID1C | Authors: | Koehler, C, Bishop, S, Dowler, E.F, Diehl, A, Schmieder, P, Leidert, M, Sundstrom, M, Arrowsmith, C.H, Wiegelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC) | Deposit date: | 2007-06-29 | Release date: | 2007-07-10 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Backbone and sidechain 1H, 13C and 15N resonance assignments of the Bright/ARID domain from the human JARID1C (SMCX) protein. Biomol.Nmr Assign., 2, 2008
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1DN3
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![BU of 1dn3 by Molmil](/molmil-images/mine/1dn3) | NMR STRUCTURE OF A MODEL HYDROPHILIC AMPHIPATHIC HELICAL BASIC PEPTIDE | Descriptor: | HUMAN PLATELET FACTOR 4, SEGMENT 59-73 | Authors: | Montserret, R, McLeish, M.J, Bockmann, A, Geourjon, C, Penin, F. | Deposit date: | 1999-12-16 | Release date: | 2000-01-12 | Last modified: | 2024-04-10 | Method: | SOLUTION NMR | Cite: | Involvement of electrostatic interactions in the mechanism of peptide folding induced by sodium dodecyl sulfate binding. Biochemistry, 39, 2000
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6FIT
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![BU of 6fit by Molmil](/molmil-images/mine/6fit) | FHIT-TRANSITION STATE ANALOG | Descriptor: | ADENOSINE MONOTUNGSTATE, FRAGILE HISTIDINE TRIAD PROTEIN | Authors: | Lima, C.D, Klein, M.G, Hendrickson, W.A. | Deposit date: | 1997-09-25 | Release date: | 1998-03-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure-based analysis of catalysis and substrate definition in the HIT protein family. Science, 278, 1997
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6GB2
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![BU of 6gb2 by Molmil](/molmil-images/mine/6gb2) | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the 39S ribosomal subunit. | Descriptor: | 'Mitochondrial ribosomal protein L30, 'Mitochondrial ribosomal protein L55, 'Mitochondrial ribosomal protein L59, ... | Authors: | Kummer, E, Leibundgut, M, Boehringer, D, Ban, N. | Deposit date: | 2018-04-13 | Release date: | 2018-08-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. Nature, 560, 2018
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6GAW
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![BU of 6gaw by Molmil](/molmil-images/mine/6gaw) | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the complete 55S ribosome. | Descriptor: | 12S ribosomal RNA, mitochondrial, 16S ribosomal RNA, ... | Authors: | Kummer, E, Leibundgut, M, Boehringer, D, Ban, N. | Deposit date: | 2018-04-13 | Release date: | 2018-08-22 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. Nature, 560, 2018
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6GAZ
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![BU of 6gaz by Molmil](/molmil-images/mine/6gaz) | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the 28S ribosomal subunit. | Descriptor: | 12S ribosomal RNA, mitochondrial, 28S ribosomal protein S18b, ... | Authors: | Kummer, E, Leibundgut, M, Boehringer, D, Ban, N. | Deposit date: | 2018-04-13 | Release date: | 2018-08-08 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. Nature, 560, 2018
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1HF6
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![BU of 1hf6 by Molmil](/molmil-images/mine/1hf6) | ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS IN THE ORTHORHOMBIC CRYSTAL FORM IN COMPLEX WITH CELLOTRIOSE | Descriptor: | ACETIC ACID, ENDOGLUCANASE B, GLYCEROL, ... | Authors: | Varrot, A, Withers, S, Vasella, A, Schulein, M, Davies, G.J. | Deposit date: | 2000-11-29 | Release date: | 2001-11-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Direct Experimental Observation of the Hydrogen-Bonding Network of a Glycosidase Along its Reaction Coordinate Revealed by Atomic Resolution Analyses of Endoglucanase Cel5A Acta Crystallogr.,Sect.D, 59, 2003
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7AVF
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![BU of 7avf by Molmil](/molmil-images/mine/7avf) | Triclinic hydrogenated hen egg-white lysozyme at 100 K (control) | Descriptor: | ACETATE ION, Lysozyme, NITRATE ION | Authors: | Ramos, J, Laux, V, Haertlein, M, Erba Boeri, E, Forsyth, V.T, Mossou, E, Larsen, S, Langkilde, A.E. | Deposit date: | 2020-11-05 | Release date: | 2021-05-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Structural insights into protein folding, stability and activity using in vivo perdeuteration of hen egg-white lysozyme. Iucrj, 8, 2021
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7AVG
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![BU of 7avg by Molmil](/molmil-images/mine/7avg) | Perdeuterated hen egg-white lysozyme at 100 K | Descriptor: | ACETATE ION, Lysozyme, NITRATE ION | Authors: | Ramos, J, Laux, V, Haertlein, M, Erba Boeri, E, Forsyth, V.T, Mossou, E, Larsen, S, Langkilde, A.E. | Deposit date: | 2020-11-05 | Release date: | 2021-05-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Structural insights into protein folding, stability and activity using in vivo perdeuteration of hen egg-white lysozyme. Iucrj, 8, 2021
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2ML8
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![BU of 2ml8 by Molmil](/molmil-images/mine/2ml8) | |
3FCH
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