3F6B
Crystal structure of benzoylformate decarboxylase in complex with the pyridyl inhibitor PAA
Summary for 3F6B
Entry DOI | 10.2210/pdb3f6b/pdb |
Related | 3F6E |
Descriptor | Benzoylformate decarboxylase, MAGNESIUM ION, 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-2-[(1S,2E)-1-hydroxy-3-pyridin-3-ylprop-2-en-1-yl]-4-methyl-1,3-thiazol-3-ium, ... (4 entities in total) |
Functional Keywords | thiamin adduct, aromatic hydrocarbons catabolism, calcium, decarboxylase, lyase, magnesium, mandelate pathway, metal-binding, thiamine pyrophosphate |
Biological source | Pseudomonas putida |
Total number of polymer chains | 1 |
Total formula weight | 56626.00 |
Authors | Brandt, G.S.,McLeish, M.J.,Kenyon, G.L.,Petsko, G.A.,Ringe, D.,Jordan, F. (deposition date: 2008-11-05, release date: 2008-12-09, Last modification date: 2023-09-06) |
Primary citation | Chakraborty, S.,Nemeria, N.S.,Balakrishnan, A.,Brandt, G.S.,Kneen, M.M.,Yep, A.,McLeish, M.J.,Kenyon, G.L.,Petsko, G.A.,Ringe, D.,Jordan, F. Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase. Biochemistry, 48:981-994, 2009 Cited by PubMed: 19140682DOI: 10.1021/bi801810h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.34 Å) |
Structure validation
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