5EDW
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4MFF
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![BU of 4mff by Molmil](/molmil-images/mine/4mff) | Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable TTP | Descriptor: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA polymerase beta, MAGNESIUM ION, ... | Authors: | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | Deposit date: | 2013-08-27 | Release date: | 2014-04-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
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4MF8
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![BU of 4mf8 by Molmil](/molmil-images/mine/4mf8) | Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template O6MG and incoming CTP | Descriptor: | DNA polymerase beta, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | Deposit date: | 2013-08-27 | Release date: | 2014-08-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structures of human DNA polymerase beta inserting bases opposite templating O6MG To be Published
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4NM1
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![BU of 4nm1 by Molmil](/molmil-images/mine/4nm1) | Structure of human DNA polymerase beta complexed with a nicked DNA containing a 8BrG-C at N-1 position and G-C at N position | Descriptor: | 5'-D(*CP*CP*GP*AP*CP*GP*(BGM)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | Authors: | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.415 Å) | Cite: | Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
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4NM2
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![BU of 4nm2 by Molmil](/molmil-images/mine/4nm2) | Structure of human DNA polymerase beta complexed with a nicked DNA containing a 8BrG-G at N-1 position and G-C at N position | Descriptor: | 5'-D(*CP*CP*GP*AP*CP*GP*(BGM)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | Authors: | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.524 Å) | Cite: | Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
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4NLK
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![BU of 4nlk by Molmil](/molmil-images/mine/4nlk) | Structure of human DNA polymerase beta complexed with 8BrG in the template base-paired with incoming non-hydrolyzable CTP | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', ... | Authors: | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.494 Å) | Cite: | Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
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4NLN
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![BU of 4nln by Molmil](/molmil-images/mine/4nln) | Structure of human DNA polymerase beta complexed with nicked DNA containing a template 8BrG and incoming CTP | Descriptor: | 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | Authors: | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.261 Å) | Cite: | Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
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4NLZ
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![BU of 4nlz by Molmil](/molmil-images/mine/4nlz) | Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template 8BrG and incoming GTP | Descriptor: | 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*AP*G)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | Authors: | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | Deposit date: | 2013-11-14 | Release date: | 2014-01-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.683 Å) | Cite: | Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
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4NXZ
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![BU of 4nxz by Molmil](/molmil-images/mine/4nxz) | DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable TTP with manganese in the active site | Descriptor: | 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | Authors: | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | Deposit date: | 2013-12-09 | Release date: | 2014-04-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.557 Å) | Cite: | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
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4NY8
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![BU of 4ny8 by Molmil](/molmil-images/mine/4ny8) | DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable CTP with manganese in the active site | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', ... | Authors: | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | Deposit date: | 2013-12-10 | Release date: | 2014-04-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.246 Å) | Cite: | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
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3NYJ
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![BU of 3nyj by Molmil](/molmil-images/mine/3nyj) | Crystal Structure Analysis of APP E2 domain | Descriptor: | Amyloid beta A4 protein, OSMIUM ION | Authors: | Ha, Y, Hu, J, Lee, S, Liu, X. | Deposit date: | 2010-07-15 | Release date: | 2011-06-01 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization. Biochemistry, 50, 2011
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3MD5
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![BU of 3md5 by Molmil](/molmil-images/mine/3md5) | Prion peptide | Descriptor: | Major prion protein | Authors: | Yee, V.C, Lee, S. | Deposit date: | 2010-03-29 | Release date: | 2011-05-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Diversity in the cross-beta spine structure of prion peptides To be Published
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3MD4
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![BU of 3md4 by Molmil](/molmil-images/mine/3md4) | Prion peptide | Descriptor: | Major prion protein | Authors: | Yee, V.C, Lee, S. | Deposit date: | 2010-03-29 | Release date: | 2011-05-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Diversity in the cross-beta spine structure of prion peptides To be Published
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1C3G
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![BU of 1c3g by Molmil](/molmil-images/mine/1c3g) | S. CEREVISIAE HEAT SHOCK PROTEIN 40 SIS1 | Descriptor: | HEAT SHOCK PROTEIN 40 | Authors: | Sha, B, Lee, S, Cyr, D. | Deposit date: | 1999-07-27 | Release date: | 2000-08-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The crystal structure of the peptide-binding fragment from the yeast Hsp40 protein Sis1. Structure, 8, 2000
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7FDA
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![BU of 7fda by Molmil](/molmil-images/mine/7fda) | CryoEM Structure of Reconstituted V-ATPase, state1 | Descriptor: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | Authors: | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | Deposit date: | 2021-07-16 | Release date: | 2021-12-22 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation. Embo J., 2021
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7FDC
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![BU of 7fdc by Molmil](/molmil-images/mine/7fdc) | CryoEM Structures of Reconstituted V-ATPase, state3 | Descriptor: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | Authors: | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | Deposit date: | 2021-07-16 | Release date: | 2021-12-22 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation. Embo J., 2021
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7FDB
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![BU of 7fdb by Molmil](/molmil-images/mine/7fdb) | CryoEM Structures of Reconstituted V-ATPase,State2 | Descriptor: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | Authors: | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | Deposit date: | 2021-07-16 | Release date: | 2021-12-22 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation. Embo J., 2021
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7FDE
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![BU of 7fde by Molmil](/molmil-images/mine/7fde) | CryoEM Structures of Reconstituted V-ATPase, Oxr1 bound V1 | Descriptor: | Oxidation resistance protein 1, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | Authors: | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | Deposit date: | 2021-07-16 | Release date: | 2021-12-29 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation. Embo J., 2021
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2X26
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![BU of 2x26 by Molmil](/molmil-images/mine/2x26) | Crystal structure of the periplasmic aliphatic sulphonate binding protein SsuA from Escherichia coli | Descriptor: | GLYCEROL, PERIPLASMIC ALIPHATIC SULPHONATES-BINDING PROTEIN | Authors: | Beale, J, Lee, S, Iwata, S, Beis, K. | Deposit date: | 2010-01-11 | Release date: | 2010-04-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of the Aliphatic Sulfonate-Binding Protein Ssua from Escherichia Coli Acta Crystallogr.,Sect.F, 66, 2010
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1B66
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![BU of 1b66 by Molmil](/molmil-images/mine/1b66) | 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE | Descriptor: | 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE, BIOPTERIN, ZINC ION | Authors: | Ploom, T, Thoeny, B, Yim, J, Lee, S, Nar, H, Leimbacher, W, Huber, R, Richardson, J, Auerbach, G. | Deposit date: | 1999-01-20 | Release date: | 1999-04-27 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic and kinetic investigations on the mechanism of 6-pyruvoyl tetrahydropterin synthase. J.Mol.Biol., 286, 1999
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1B6Z
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![BU of 1b6z by Molmil](/molmil-images/mine/1b6z) | 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE | Descriptor: | 6-pyruvoyl tetrahydropterin synthase, ZINC ION | Authors: | Ploom, T, Thoeny, B, Yim, J, Lee, S, Nar, H, Leimbacher, W, Huber, R, Richardson, J, Auerbach, G. | Deposit date: | 1999-01-18 | Release date: | 2000-01-21 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystallographic and kinetic investigations on the mechanism of 6-pyruvoyl tetrahydropterin synthase. J.Mol.Biol., 286, 1999
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7X1K
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7STO
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![BU of 7sto by Molmil](/molmil-images/mine/7sto) | Chitin Synthase 2 from Candida albicans bound to polyoxin D | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-{(2R,3R,4S,5R)-5-[(S)-{[(2S,3S,4S)-2-amino-5-(carbamoyloxy)-3,4-dihydroxypentanoyl]amino}(carboxy)methyl]-3,4-dihydroxyoxolan-2-yl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid (non-preferred name), Chitin synthase | Authors: | Ren, Z, Chhetri, A, Lee, S, Yokoyama, K. | Deposit date: | 2021-11-14 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structural basis for inhibition and regulation of a chitin synthase from Candida albicans. Nat.Struct.Mol.Biol., 29, 2022
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7STM
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![BU of 7stm by Molmil](/molmil-images/mine/7stm) | Chitin Synthase 2 from Candida albicans bound to UDP-GlcNAc | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Chitin synthase, MAGNESIUM ION, ... | Authors: | Ren, Z, Chhetri, A, Lee, S, Yokoyama, K. | Deposit date: | 2021-11-14 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Structural basis for inhibition and regulation of a chitin synthase from Candida albicans. Nat.Struct.Mol.Biol., 29, 2022
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7STN
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![BU of 7stn by Molmil](/molmil-images/mine/7stn) | Chitin Synthase 2 from Candida albicans bound to Nikkomycin Z | Descriptor: | (2S)-{[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid (non-preferred name), 1,2-Distearoyl-sn-glycerophosphoethanolamine, Chitin synthase | Authors: | Ren, Z, Chhetri, A, Lee, S, Yokoyama, K. | Deposit date: | 2021-11-14 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Structural basis for inhibition and regulation of a chitin synthase from Candida albicans. Nat.Struct.Mol.Biol., 29, 2022
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