7STO

Chitin Synthase 2 from Candida albicans bound to polyoxin D

Summary for 7STO

Entry DOI	10.2210/pdb7sto/pdb
EMDB information	25435
Descriptor	Chitin synthase, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-{(2R,3R,4S,5R)-5-[(S)-{[(2S,3S,4S)-2-amino-5-(carbamoyloxy)-3,4-dihydroxypentanoyl]amino}(carboxy)methyl]-3,4-dihydroxyoxolan-2-yl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid (non-preferred name) (3 entities in total)
Functional Keywords	chitin synthesis, glycosyltransferase, polyoxin d, membrane protein, transferase
Biological source	Candida albicans
Total number of polymer chains	2
Total formula weight	245623.75
Authors	Ren, Z.,Chhetri, A.,Lee, S.,Yokoyama, K. (deposition date: 2021-11-14, release date: 2022-07-13, Last modification date: 2022-07-27)
Primary citation	Ren, Z.,Chhetri, A.,Guan, Z.,Suo, Y.,Yokoyama, K.,Lee, S.Y. Structural basis for inhibition and regulation of a chitin synthase from Candida albicans. Nat.Struct.Mol.Biol., 29:653-664, 2022 Cited by PubMed: 35788183 DOI: 10.1038/s41594-022-00791-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.15 Å)

Structure validation