7STN
Chitin Synthase 2 from Candida albicans bound to Nikkomycin Z
Summary for 7STN
| Entry DOI | 10.2210/pdb7stn/pdb |
| EMDB information | 25434 |
| Descriptor | Chitin synthase, 1,2-Distearoyl-sn-glycerophosphoethanolamine, (2S)-{[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid (non-preferred name) (3 entities in total) |
| Functional Keywords | chitin synthesis, glycosyltransferase, nikkomycin z, membrane protein, transferase |
| Biological source | Candida albicans |
| Total number of polymer chains | 2 |
| Total formula weight | 245571.85 |
| Authors | Ren, Z.,Chhetri, A.,Lee, S.,Yokoyama, K. (deposition date: 2021-11-14, release date: 2022-07-13, Last modification date: 2022-07-27) |
| Primary citation | Ren, Z.,Chhetri, A.,Guan, Z.,Suo, Y.,Yokoyama, K.,Lee, S.Y. Structural basis for inhibition and regulation of a chitin synthase from Candida albicans. Nat.Struct.Mol.Biol., 29:653-664, 2022 Cited by PubMed: 35788183DOI: 10.1038/s41594-022-00791-x PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.19 Å) |
Structure validation
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