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PDB: 322 results

4Z6C
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BU of 4z6c by Molmil
Structure of human DNA polymerase beta 279NA mutant complexed with G in the template base paired with incoming non-hydrolyzable CTP
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.-C, Lee, S.
Deposit date:2015-04-04
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.677 Å)
Cite:Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase beta.
Biochem. J., 475, 2018
4Z6D
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BU of 4z6d by Molmil
Structure of human DNA polymerase beta 279NA mutant complexed with G in the template base paired with incoming non-hydrolyzable TTP
Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.-C, Lee, S.
Deposit date:2015-04-04
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase beta.
Biochem. J., 475, 2018
7KLF
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BU of 7klf by Molmil
Ternary structure of Dpo4 bound to G in the template base paired with incoming dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*TP*AP*AP*CP*GP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ...
Authors:Koag, M.-C, Lee, S.
Deposit date:2020-10-30
Release date:2021-11-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable ATP
To Be Published
7KLE
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BU of 7kle by Molmil
Ternary structure of Dpo4 bound to N7mG in the template base paired with incoming dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*TP*AP*AP*CP*(FMG)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ...
Authors:Koag, M.-C, Lee, S.
Deposit date:2020-10-30
Release date:2021-11-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable ATP
To Be Published
7L69
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BU of 7l69 by Molmil
Crystal structure of human polymerase eta complexed with syn N7-benzylguanine
Descriptor: DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(*CP*AP*TP*(7BG)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA polymerase eta
Authors:Jung, H, Lee, S.
Deposit date:2020-12-23
Release date:2022-01-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of human polymerase eta complexed with syn N7-benzylguanine
To Be Published
5CHZ
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BU of 5chz by Molmil
Structure of wild-type human MBD4 bound to a G:T mismatch
Descriptor: 12-mer DNA(G), 5-mer DNA, 7-mer DNA, ...
Authors:Ouzon-Shubeita, H, Lin, Y.-L, Lee, S.
Deposit date:2015-07-10
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure of wild-type human MBD4 bound to a G:T mismatch
To Be Published
5DB6
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BU of 5db6 by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the N7MG base paired with a dC
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*(FMG)P*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-20
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5DBC
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BU of 5dbc by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the dG base paired with a dG
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5DB7
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BU of 5db7 by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the N7MG base paired with a dT
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*(FMG)P*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.209 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
2N8V
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BU of 2n8v by Molmil
An NMR/SAXS structure of the PKI domain of the honeybee dicistrovirus, Israeli acute paralysis virus (IAPV) IRES
Descriptor: RNA (70-MER)
Authors:Au, H.H, Cornilescu, G, Mouzakis, K.D, Burke, J.E, Ren, Q, Lee, S, Butcher, S.E, Jan, E.
Deposit date:2015-10-27
Release date:2015-11-11
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Global shape mimicry of tRNA within a viral internal ribosome entry site mediates translational reading frame selection.
Proc.Natl.Acad.Sci.USA, 112, 2015
2K3M
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BU of 2k3m by Molmil
Rv1761c
Descriptor: Rv1761c, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Authors:Page, R.C, Moore, J.D, Lee, S, Opella, S.J, Cross, T.A.
Deposit date:2008-05-14
Release date:2009-01-06
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Backbone structure of a small helical integral membrane protein: A unique structural characterization.
Protein Sci., 18, 2009
2HNH
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BU of 2hnh by Molmil
Crystal structure of the catalytic alpha subunit of E. coli replicative DNA polymerase III
Descriptor: DNA polymerase III alpha subunit, PHOSPHATE ION
Authors:Meindert, M.H, Georgescu, R.E, Lee, S, O'Donnell, M, Kuriyan, J.
Deposit date:2006-07-12
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Catalytic alpha Subunit of E. coli Replicative DNA Polymerase III.
Cell(Cambridge,Mass.), 126, 2006
3NYL
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BU of 3nyl by Molmil
The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain
Descriptor: Amyloid beta (A4) protein (Peptidase nexin-II, Alzheimer disease), isoform CRA_b
Authors:Ha, Y, Hu, J, Lee, S, Liu, X, Wang, Y.
Deposit date:2010-07-15
Release date:2011-07-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain.
Mol.Cell, 15, 2004
8JBP
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BU of 8jbp by Molmil
Crystal structure of triosephosphate isomerase from Leishmania orientalis at 1.45 angstroms resolution with an arsenic atom bound at Cys57
Descriptor: ARSENIC, Triosephosphate isomerase
Authors:Kuaprasert, B, Leartsakulpanich, U, Riangrungroj, P, Pornthanakasem, W, Suginta, W, Robinson, R.C, Zhou, Y, Mungthin, M, Leelayoova, S, Saehlee, S, Choowongkomon, K.
Deposit date:2023-05-09
Release date:2024-05-15
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Leishmania orientalis triosephosphate isomerase crystal structure at 1.45 angstroms resolution and its potential specific inhibitors
To be published
8J7C
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BU of 8j7c by Molmil
Crystal structure of triosephosphate isomerase from Leishmania orientalis at 1.88A with an arsenic ion bound at Cys57
Descriptor: ARSENIC, Triosephosphate isomerase
Authors:Kuaprasert, B, Attarataya, J, Riangrungroj, P, Pornthanakasem, W, Suginta, W, Mungthin, M, Leelayoova, S, Choowongkomon, K, Leartsakulpanich, U.
Deposit date:2023-04-27
Release date:2024-05-01
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Leishmania orientalis triosephosphate isomerase crystal structure at 1.45 angstroms resolution and its potential specific inhibitors
To be published
2AKP
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BU of 2akp by Molmil
Hsp90 Delta24-N210 mutant
Descriptor: ATP-dependent molecular chaperone HSP82
Authors:Richter, K, Moser, S, Hagn, F, Friedrich, R, Hainzl, O, Heller, M, Schlee, S, Kessler, H, Reinstein, J, Buchner, J.
Deposit date:2005-08-03
Release date:2006-01-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Intrinsic inhibition of the Hsp90 ATPase activity.
J.Biol.Chem., 281, 2006
5EY5
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BU of 5ey5 by Molmil
LBCATS
Descriptor: LBCA-b, LBCATS-a, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Busch, F, Rajendran, C, Schlee, S, Heyn, K, Merkl, R, Sterner, R.
Deposit date:2015-11-24
Release date:2016-04-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.972 Å)
Cite:LBCATS
To Be Published
3GBR
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BU of 3gbr by Molmil
Anthranilate phosphoribosyl-transferase (TRPD) double mutant D83G F149S from S. solfataricus
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, DI(HYDROXYETHYL)ETHER, ...
Authors:Bruning, M, Schlee, S, Deuss, M, Ivens, A, Mayans, O, Sterner, R.
Deposit date:2009-02-20
Release date:2009-12-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Activation of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus by removal of magnesium inhibition and acceleration of product release
Biochemistry, 48, 2009
4J5N
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BU of 4j5n by Molmil
Crystal Structure of a Deinococcus radiodurans PTE-like lactonase (drPLL) mutant Y28L/D71N/E101G/E179D/V235L/L270M
Descriptor: COBALT (II) ION, Phosphotriesterase, putative
Authors:Meier, M.M, Rajendran, C, Malisi, C, Fox, N.G, Xu, C, Schlee, S, Barondeau, D.P, Hocker, B, Sterner, R, Raushel, F.M.
Deposit date:2013-02-08
Release date:2013-07-24
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template.
J.Am.Chem.Soc., 135, 2013
4GNJ
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BU of 4gnj by Molmil
Crystal Structure Analysis of Leishmania siamensis Triosephosphate Isomerase
Descriptor: ARSENIC, SODIUM ION, Triosephosphate isomerase
Authors:Kuaprasert, B, Riangrungroj, P, Pornthanakasem, W, Suginta, W, Mungthin, M, Leelayoova, S, Leartsakulpanich, U.
Deposit date:2012-08-17
Release date:2013-09-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal Structure Analysis of Leishmania siamensis Triosephosphate Isomerase
To be Published
4J35
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BU of 4j35 by Molmil
Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template
Descriptor: COBALT (II) ION, Phosphotriesterase, putative
Authors:Sterner, R, Raushel, F, Meier, M, Rajendran, C, Malisi, C, Fox, N, Schlee, S, Barondeau, D, Cker, B.H.
Deposit date:2013-02-05
Release date:2013-07-24
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (1.783 Å)
Cite:Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template.
J.Am.Chem.Soc., 135, 2013
5BMM
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BU of 5bmm by Molmil
Src in complex with DNA-templated macrocyclic inhibitor MC25b
Descriptor: Proto-oncogene tyrosine-protein kinase Src, macrocyclic inhibitor MC25b
Authors:Georghiou, G, Guja, K.E, Aleem, S, Kleiner, R.E, Liu, D.R, Miller, W.T, Garcia-Diaz, M, Seeliger, M.A.
Deposit date:2015-05-22
Release date:2016-09-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles.
Cell Chem Biol, 23, 2016

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