4J5N

Crystal Structure of a Deinococcus radiodurans PTE-like lactonase (drPLL) mutant Y28L/D71N/E101G/E179D/V235L/L270M

Summary for 4J5N

Entry DOI	10.2210/pdb4j5n/pdb
Descriptor	Phosphotriesterase, putative, COBALT (II) ION (3 entities in total)
Functional Keywords	metalloenzyme, tim barrel, hydrolase, nerve agent, phosphotriesterase, lactonase
Biological source	Deinococcus radiodurans
Total number of polymer chains	1
Total formula weight	34821.97
Authors	Meier, M.M.,Rajendran, C.,Malisi, C.,Fox, N.G.,Xu, C.,Schlee, S.,Barondeau, D.P.,Hocker, B.,Sterner, R.,Raushel, F.M. (deposition date: 2013-02-08, release date: 2013-07-24, Last modification date: 2023-12-06)
Primary citation	Meier, M.M.,Rajendran, C.,Malisi, C.,Fox, N.G.,Xu, C.,Schlee, S.,Barondeau, D.P.,Hocker, B.,Sterner, R.,Raushel, F.M. Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template. J.Am.Chem.Soc., 135:11670-11677, 2013 Cited by PubMed: 23837603 DOI: 10.1021/ja405911h PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation