Structure of human DNA polymerase beta Host-Guest complex with the N7MG base paired with a dC

Summary for 5DB6

Related5DB7 5DB8 5DB9 5DBA 5DBB 5DBC
DescriptorDNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*(FMG)P*AP*TP*GP*CP*GP*A)-3'), ... (6 entities in total)
Functional Keywordshuman dna polymerase, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total molecular weight47785.89
Koag, M.C.,Lee, S. (deposition date: 2015-08-20, release date: 2015-11-11, Last modification date: 2019-02-13)
Primary citation
Kou, Y.,Koag, M.C.,Lee, S.
N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137:14067-14070, 2015
PubMed: 26517568 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.5b10172
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2653 0.3% 1.8% 1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5db6
no rotation
Molmil generated image of 5db6
rotated about x axis by 90°
Molmil generated image of 5db6
rotated about y axis by 90°